The significant prevalence and severe medical social consequences of comorbidity dictate the need to determine etiopathogenetic risk factors that contribute its formation. Purpose study: study associations metabolic (arterial hypertension, obesity, hyperglycemia, dyslipidemia, hyperuricemia, increased serum concentration C-reactive protein (CRP) with a high degree in patients somatic pathology. Material methods . An analytical retrospective was carried out including data from records 5296 at...

Purpose. To study the dependence of frequency occurrence and values indicators basic risk factors for chronic non-communicable diseases on degree transnosological polymorbidity in patients a clinic general therapeutic profile period from 2003 to 2013. Material methods. The analysis 5019 medical records (2501 men, 2518 women) treated RIECM, Novosibirsk, was carried out. Transnosological evaluated average number nosologies accordance with International Classification Diseases, 10th revision...

To examine the incidence of polymorbidity (PM) and changes in its rates 2003 to 2011 cardiac gastroenterologic patients living Novosibirsk Region Republic Sakha (Yakutia) accordance with gender, occupation, residence.The dynamics PM was analyzed 13 496 who had been examined treated at Cardiology Gastroenterology Departments, Therapeutic Clinic, Research Institute Experimental Clinical Medicine (Novosibirsk), 2003-2011. The study used an archival research method a statistical analysis all...

Aim. To study the associations of frequency and values parameters main risk factors (RF) cardiovascular diseases (CVD) degree transnosological polymorbidity (PM) in patients with nonalcoholic fatty liver disease (NAFLD). Material methods . The analysis 3667 medical records (men, women) treated clinic Research Institute Experimental Clinical Medicine (Novosibirsk) was carried out. Index evaluated by number nosological forms accordance International Classification Diseases, 10th revision...

Purpose. To study regional features of the association frequency occurrence and magnitude indices main risk factors for chronic non-communicable diseases (RF CNCD) with degree transnosological polymorbidity (PM) in male residents Novosibirsk Region (NR) Saha (Yakutia) Republic. Methods. The analysis 10 187 medical records patients therapeutic profile (men), examined treated clinic Federal Research Center Fundamental Translational Medicine, was carried out. index assessed by number...

Background. Hypertension (HTN) is often combined with other diseases, that significantly complicate its course, worsen the prognosis, interfere therapeutic and preventive measures. Therefore, assessing development structure of polymorbidity (PM) in hypertension a relevant issue. Objective . To study degree PM hypertensive patients depending on age gender. Design methods. We conducted an analysis 20 560 case histories HTN without (men women), inhabitants West Siberia-Novosibirsk region, who...

Aim of the study was to investigate role C-reactive protein as an indicator multimorbidity in patients with arterial hypertension. Material and methods. A retrospective archival data 1958 hypertension who were examined treated at clinic Federal Research Center for Fundamental Translational Medicine (Novosibirsk) carried out. 2 groups allocated depending on concentration blood serum: normal elevated (> 5 mg/l). comparative analysis severity polymorbidity, well clinical, laboratory...

The aim of the study was to identify features unfavorable clinical course a new coronavirus infection. Material and methods . analysis data, laboratory results comorbidity 168 patients with confirmed diagnosis infection aged 65,0 [57,0; 74,0] years carried out. Two groups were distinguished – 126 persons moderate recovery in outcome disease 42 severe fatal disease. Transnosological polymorbidity assessed by average number nosologies corresponding three-digit ICD-10 rubricification,...

Aim of the study was to identify features susceptibility a new coronavirus infection СOVID-19 depending on gender, age, social factors and polymorbidity. Material methods . An analysis structural in 620 patients who underwent examination treatment at Federal Research Center Fundamental Translational Medicine clinic (Novosibirsk) carried out. The were divided into 2 groups: main group (group 2, age 56.4 ± 0.7 years) included 272 COVID-19, confirmed by positive PCR test or antibody testing,...

Introduction. The emergence of new strains the SARS-CoV-2 virus and an increase in number cases around world requires further study epidemiology, clinical peculiarities course complications this disease. Aim. Revealing characteristic spread, picture significance manifestations a novel coronavirus infection outpatients. Materials methods. An analysis was carried out 387 outpatient records children with confirmed (COVID-19) (group 1), as well 9 followed-up by cardiologist for pericarditis...

The aim of the study was to characteristics content certain cytokines in serum as indicators immune response viral infections accompanied by diarrhea syndrome children. Materials and research methods. A survey conducted 92 children aged 3 months 15 years with acute respiratory hospitalized hospital No. 6 Novosibirsk first 2 days from onset disease. Two groups were formed — group 1 patients diarrheal signs system damage. Group isolated lesions tract. In all children, genetic material viruses...

Purpose. To assess changes in nucleic acid (NA) metabolism severe burn injury and to develop recommendations for correction of the alimentary status taking into account NA metabolism. Materials methods. All patients (37 with II–III degree thermal burns a area more than 40%) were divided 2 groups: Group I included survivors (23 patients), group II consisted deceased. The intensity was assessed based on dynamics uric (UA) oligonucleotides serum concentrations. Results. In acute period injury,...

Aim of the study was to investigate peculiarities relationship polymorbid pathology in arterial hypertension with disorders lipid, purine and carbohydrate metabolism. Material methods . Patients presence pathology, who underwent examination treatment at clinic Federal Research Center for Fundamental Translational Medicine (Novosibirsk), were examined. A total 9775 people The patients divided into 2 groups: dyslipidemia absence (n = 561(252 men (44.9 %), 309 women (55.1 average age 57.1 ±...

The article presents result of analysis indicator polymorbidity in sampling 9871 patients therapeutic clinic the research institute experimental and clinical medicine (Novosibirsk)during 2003-2011. study was carried out using archive method with statistical all nosologic forms, groups classes ICD-10 irrespective particular diagnosis being main or concomitant. gender differences trans-systemic during 2003-2011consisted that males its increasing more dynamic than females. is correlated social...