A5072245551- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- COVID-19 and healthcare impacts
- BRCA gene mutations in cancer
- Cervical Cancer and HPV Research
- Intraperitoneal and Appendiceal Malignancies
- Colorectal and Anal Carcinomas
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Neuroendocrine Tumor Research Advances
- Sarcoma Diagnosis and Treatment
- Lung Cancer Research Studies
- Gynecological conditions and treatments
- Gestational Trophoblastic Disease Studies
- Radiomics and Machine Learning in Medical Imaging
- Microgrid Control and Optimization
- Circular RNAs in diseases
- Minimally Invasive Surgical Techniques
- Diagnosis and treatment of tuberculosis
- Cancer survivorship and care
- MRI in cancer diagnosis
- Smart Grid Energy Management
- Prenatal Screening and Diagnostics
Gynecologic Oncology Group
2025
Icahn School of Medicine at Mount Sinai
2015-2024
Mount Sinai Hospital
2010-2024
The Mount
2023
Mount Sinai Hospital
2021-2022
Mount Sinai Beth Israel
2013-2021
Technical University of Sofia
2021
Institute for Nuclear Research and Nuclear Energy
2021
Mount Sinai Hospital
2019-2021
Mount Sinai Medical Center
2012-2014
Ovarian cancer is a leading cause of deaths among women. Effective targets to treat advanced epithelial ovarian (EOC) and biomarkers predict treatment response are still lacking because the complexity pathways involved in progression. Here we show that miR-181a promotes TGF-β-mediated epithelial-to-mesenchymal transition via repression its functional target, Smad7. phosphorylated Smad2 enriched recurrent compared with matched-primary tumours their expression associated shorter time...
BackgroundThe coronavirus disease 2019 pandemic has resulted in unprecedented challenges for the oncology community. For people living with cancer, treatments are interrupted, surgeries cancelled, and regular evaluations rescheduled. People cancer their physicians must balance plausible fears of treatment consequences delaying care.ObjectiveWe aim to evaluate experience women ovarian during pandemic.Study DesignWomen a current or previous diagnosis completed an online survey focusing on...
Introduction: It has been hypothesized that the supradiaphragmatic lymph nodes serve as principal for lymphatic drainage of entire peritoneal cavity. The purpose this study was to determine prognostic significance enlarged noted on preoperative computed tomographic (CT) scan in patients undergoing primary cytoreduction advanced epithelial ovarian cancer (EOC). Methods: We performed a retrospective chart review all with stage III and IV EOC according International Federation Gynecology...
TPS5623 Background: Sacituzumab govitecan (SG) is an antibody-drug conjugate (ADC) composed of the irinotecan active metabolite SN-38 (govitecan) covalently linked to a humanized monoclonal antibody (hRS7) targeting trophoblastic cell-surface antigen-2 (Trop-2). has demonstrated in vitro and vivo activity against multiple solid tumors, including ovarian cancer endometrial cancer. The Basket Trial, phase I/II study single agent sacituzumab patients with epithelial cancers, showed clinical...
The aim of this study is to determine the role liver metastatectomy in morbidity and survival patients with recurrent ovarian carcinoma.We retrospectively reviewed records all who had undergone hepatic resection for metastases from carcinoma at time cytoreductive surgery our institution 1988 2012. Kaplan-Meier method was used analysis. A total 76 met inclusion criteria as part during period. Of these patients, 27 underwent secondary cytoreduction, that are focus analysis.Median overall group...
Endometrial cancer is the most common gynecologic malignancy in industrialized countries, and both its incidence associated mortality are increasing. The “liquid biopsy” becoming an important transformative precision oncology tool, but barriers intrinsic to blood sampling have limited use early detection. We hypothesized that using a more targeted sample for analysis—namely, uterine lavage—should provide sensitive specific diagnostic test endometrial cancer. Using custom 12-gene panel,...
Our aim was to assess current surgical practices and use of adjuvant therapy in the treatment FIGO (International Federation Gynecology Obstetrics) stage I endometrioid endometrial cancer.A 19-question survey developed sent all Society Gynecologic Oncologist members by e-mail. Data were collected anonymously using Internet-based software. Respondents asked questions regarding preoperative evaluation, approach, lymph node dissection (LND), therapy.A total 1399 surveys distributed, 320 (23%)...
► 33 years old woman diagnosed with choriocarcinoma after delivery, her newborn son the same diagnosis. Case of transplasental dissemination choriacarcinoma. Advanced disease both in mother and infant.
Constitutional trisomy 8 mosaicism (CT8M) in liveborns is typically caused by mitotic non-disjunction and exhibits wide phenotypic variability. By contrast, CT8M due to meiotic errors usually results miscarriage. We describe a case of paternal meiosis II error. The patient, 32-year-old woman, was phenotypically normal except for history recurrent aphthous ulcers since childhood 4-year macrocytosis. were refractory steroids, but responded well thalidomide. To the best our knowledge, this...
Mounting evidence suggests disproportionate coronavirus disease 2019 (COVID-19) hospitalizations and deaths because of racial disparities. The association race in a cohort gynecologic oncology patients with severe acute respiratory syndrome-coronavirus 2 infection is unknown. Data were abstracted from COVID-19 among 8 New York City area hospital systems. A multivariable mixed-effects logistic regression model accounting for county clustering was used to analyze COVID-19-related...
The aim of this paper is to present a case cesarean section ectopic pregnancy (CSP) diagnosed in the second trimester and perform literature review current guidelines for management CSP trimester. This was exempt from Mount Sinai IRB. 35-year-old P1122 at 13w4d who presented our hospital with vaginal spotting abdominal pain. patient found have placenta increta. There are no CSP, published material minimal. A completed demonstrated two cases one series on existing CSP. Our underwent an...
Previvors are becoming more aware of the option risk-reducing salpingectomy with delayed oophorectomy (RRS-DO) to mitigate their risk ovarian cancer. In this qualitative study, we explored clinical and non-clinical factors that impacted previvors' decision-making pursue RRS-DO as a reduction strategy.Semi-structured telephone interviews were conducted previvors transcribed verbatim. Using ATLAS.ti® software, two primary investigators interpreted data through thematic analysis. After coding...
A carcinoid tumor occurring in the endometrium has been documented literature, but there is no report regard to metastasis endometrium.