A5058939582- Breast Cancer Treatment Studies
- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Breast Lesions and Carcinomas
- Cancer Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Thyroid Disorders and Treatments
- Voice and Speech Disorders
- Parathyroid Disorders and Treatments
- Cancer Immunotherapy and Biomarkers
- T-cell and Retrovirus Studies
- Gastrointestinal Tumor Research and Treatment
- Cancer Cells and Metastasis
- Metastasis and carcinoma case studies
- Advanced Breast Cancer Therapies
- Bone health and treatments
- Gastrointestinal disorders and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Pathology Studies
- Brain Metastases and Treatment
- Neuroendocrine Tumor Research Advances
- Anorectal Disease Treatments and Outcomes
- Lung Cancer Research Studies
- Liver Disease Diagnosis and Treatment
- Vector-Borne Animal Diseases
Nagasaki Medical Center
2016-2025
Nagasaki University
2003-2017
Nagasaki Prefectural Shimabara High School
2008-2010
American Society of Colon and Rectal Surgeons
2009
University of Minnesota
2006-2009
University of Kochi
2006
Nikon (United States)
1977
Osaka Prefectural Institute of Public Health
1968
Nara Medical University
1967
Recurrent rectal prolapse is an unresolved problem and the optimal treatment debated. This study was designed to review patterns of care outcomes in a large cohort patients after surgery for recurrent prolapse.From 685 who underwent operative repair full-thickness external prolapse, we identified 78 (70 females; mean age, 66.9 years) recurrence. We reviewed subsequent management these patients.Mean interval their first recurrence 33 (range, 1-168) months. There were significantly more...
Several single nucleotide polymorphisms (SNP) have been identified to be associated with the risk for differentiated thyroid cancer in populations of distinct ethnic background. The relationship these genetic markers a benign tumor thyroid, follicular adenoma (FA), is not well established.In multicenter retrospective case-control study, five cancer-related SNPs-rs966513 (9q22.33, FOXE1), rs944289 (14q13.3, PTCSC3), rs2439302 (8p12, NRG1), rs1867277 (9q22.23, and rs6983267 (8q24,...
Gallbladder small cell carcinoma (SCC) comprises only 0.5 % of all gallbladder cancer and consists aggressive tumors with poor survival outcomes against current treatments. These are most common in elderly females, particularly those cholecystolithiasis. We report the case a 79-year-old woman carcinoma. The patient had intermittent right upper quadrant abdominal pain was admitted to our hospital due suspected acute cholecystitis. She regularly received medical treatment for diabetes,...
Human T-cell leukemia virus type-1 (HTLV-1) is the etiological agent of adult (ATL), and leukemic cells always carry proviral genome monoclonally integrated into their host genomes at same sequence site, designated as monoclonal integration. Using Southern blot hybridization (SBH) sequenced tagged site polymerase chain reaction assays, we examined status in 558 clinical specimens from 350 patients who are suspected to have ATL. A total 321 (57.5%) 241 showed positive results for integration...
This study was designed to analyze the incidence, management, and outcome of pouch sinuses after ileal pouch-anal anastomosis at one institution.We identified 282 patients between 1992 2002 who had a pouchogram before planned ileostomy closure. The management with pouchograms revealing were reviewed.Twenty-two (7.8 percent) sinus pouchogram. Nineteen observed underwent repeat Of these, ten resolution (mean, 3.6 months) successful Eight examination under anesthesia +/- debridement. Six these...
We developed a real-time (RT) PCR quantitative assay to measure the level of integrated viral genome HTLV-1 in host peripheral blood-mononuclear cells (PB-MNC) from healthy carriers and patients with adult T-cell leukemia (ATL). All clinical specimens were serologically molecularly characterized by enzyme-linked immunosorbent (ELISA) Southern blot hybridization (SBH) analyses. The system for quantifying proviral copy was sensitive, accurate, reproducible over wide range density 100 0.1%...
The aim was to measure female sexual function after total proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis using a validated scoring system and determine the impact of pouch on function.A cross-sectional survey performed modified version Female Sexual Function Index (FSFI-m). Measures function, including Faecal Incontinence Severity Index, were also evaluated.Of 166 women eligible inclusion, 90 responded questionnaires 83 these reported activity. mean age 38.4 years...
Despite the survival benefit and acceptable tolerability of eribulin for advanced/metastatic breast cancer (MBC) patients pretreated with anthracyclines taxanes, there is limited evidence clinical early use. We investigated efficacy safety first- to third-line use in MBC.In this phase II, open-label, single-arm study conducted at 14 sites Kyushu, Japan, women histologically confirmed human epidermal growth factor receptor 2-negative MBC were enrolled between December 1, 2011 November 30,...
Abstract We evaluated the associations between tumor‐infiltrating lymphocytes ( TIL ) including CD 8‐positive [+] in ductal carcinoma situ DCIS and histopathologic factors, particularly spontaneous “healing” immunohistochemical IHC )‐based subtypes, to clarify effects of host immune response cancer cells proliferation during early carcinogenesis for breast cancer. This cohort enrolled 82 patients. examined relationships clinicopathologic factors age, architecture, Van Nuys classification,...
<title>Abstract</title> Background Sentinel lymph node biopsy (SLNB) has become a standard procedure for patients with breast cancer (BC) without clinically evident axillary metastasis. However, its role in cT3-4cN0 BC remains underexplored, leading to uncertainty regarding safety. Methods This retrospective, multicenter observational study included cT3-4cN0M0 who underwent radical surgery between 2006 and 2016. Patients were divided into an SLNB group, which those exclusively ALND after...
576 Background: Axillary management after sentinel lymph node biopsy (SLNB) is still debated for clinically node-positive breast cancer (BC) patients treated with neoadjuvant chemotherapy (NAC). The Japanese Society Sentinel Node Navigation Surgery conducted a prospective non-randomized phase 2 study (SHARE study, UMIN000030558). False-negative rate (FNR) as the primary endpoint was reported at ASCO2023. In brief, it 11.5% (90% confidence interval, 5.5% and 20.5%). When multimodal imaging, 1...
How breast cancer subtypes should affect treatment decisions for patients with brain metastases is unclear. We analyzed local treatments and their outcomes according to subtype in metastases.We reviewed records database information women treated at the National Kyushu Cancer Center between 2001 2010. Patients were divided into three groups: Luminal (estrogen receptor positive and/or progesterone positive, but human epidermal growth factor 2 negative); triple negative negative, negative).Of...
Aims While cancer immunity is involved in tumour progression from the very early stage, no detailed study has been reported on relationship between ‘early-stage’ breast and tumour-infiltrating lymphocytes (TILs). We focused microinvasive carcinoma to investigate histological factors ‘early’ cancer. Methods Of 2593 resected carcinomas, 46 carcinomas (1.8%) were included. The relationships characteristics (invasive form, grade, comedo, subtype) immunological (TIL, healing) examined. invasive...
Splenic cyst is a relatively rare disease; however, the occurrence of complications associated with its rupture even more rare. A 20-year-old female patient who had severe abdominal and left shoulder pain was admitted to our hospital. The patient's abdomen hard tender touch she presented high fever. serum levels tumor markers carbohydrate antigen 19-9, cancer 125 carcinoembryonic were high. Ultrasonography computed tomography showed an 11-cm multilocular cystic lesion in spleen presence free...
The systemic inflammatory score (SIS), a new marker based on combination of the lymphocyte-to-monocyte ratio (LMR) and serum albumin concentration, has been reported to be useful prognostic for several malignancies. authors conducted this retrospective study data from cohort esophageal cancer patients undergoing potentially curative resection clarify value SIS as clinical outcome in population.
The incidence of thyroid metastasis among colorectal cancer patients is extremely rare. We report a case colonic adenocarcinoma to the gland with treatment lung and liver metastases, in 61-year-old woman history colon cancer. She showed mass related 3-month hoarseness. Physical imaging examinations disclosed diffuse large swollen cervical lymph nodes. Fine-needle aspiration cytology suggested malignancy. patient underwent total thyroidectomy. Histopathological examination immunohistochemical...
Background: The axillary lymph node status is an important prognostic factor of breast cancer. This study explores the predictive factors for sentinel (SLN) metastasis among preoperative clinicopathological features, including impaired glucose tolerance (IGT). Methods: comprised patients diagnosed with cancer who underwent surgery at Nagasaki Harbor Medical Center between April 2014 and December 2019. assessed using univariate multivariate analyses were data these cancers, patient age,...
To discuss prediction of vapor-liquid equilibria with esterification on the basis ASOG model, infinite-dilution binary activity coefficients were measured for five systems in 40°-100°C range by an ebulliometric method. The are methyl acetate-n-heptane, ethyl acetate-ethanol, acetate-water, acetic acid-n-heptane, and acid-ethyl acetate. group Wilson parameters any system made up CH2, OH, COO, COOH groups determined coefficients. Vapor-liquid predicted three quaternary 26 ternary involving...