- Tryptophan and brain disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Influenza Virus Research Studies
- Salivary Gland Disorders and Functions
- Psoriasis: Treatment and Pathogenesis
- Schizophrenia research and treatment
- Immunodeficiency and Autoimmune Disorders
- Tuberculosis Research and Epidemiology
- Erythropoietin and Anemia Treatment
- Dermatology and Skin Diseases
- Occupational and environmental lung diseases
- Stress Responses and Cortisol
- Metabolism, Diabetes, and Cancer
- Rheumatoid Arthritis Research and Therapies
- Biomarkers in Disease Mechanisms
- Vestibular and auditory disorders
- Diet and metabolism studies
- Growth Hormone and Insulin-like Growth Factors
- Iron Metabolism and Disorders
- Cancer-related molecular mechanisms research
- Regulation of Appetite and Obesity
- Thyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Air Quality and Health Impacts
University of Ioannina
2008-2024
University Hospital of Ioannina
2011-2014
University of Siena
2008
Hyperprolactinaemia as a side effect of dopamine receptor blockers is common in patients with schizophrenia and other psychotic disorders may lead to amenorrhoea, galactorrhoea, hypogonadism, subfertility osteoporosis. The aim our study was determine whether hyperprolactinaemia occurs also prior any antipsychotic treatment.Serum prolactin, thyroid-stimulating hormone (TSH), triiodothyronine (T3), free tetraiodothyronine (FT4) cortisol levels were measured 40 newly diagnosed, drug naïve, age...
Inhabitants of Metsovo, NW Greece, have been exposed to an asbestos whitewash, resulting in malignant pleural mesothelioma (MPM) and calcifications (PCs). Interestingly, those with PCs (PC(+)) are less prone MPM. They also lymphocytic alveolitis, differences bronchoalveolar lavage (BAL) proteins, compared without (PC(-)). This may mean a different response the fiber leading susceptibility neoplasia. To further evaluate this, proteomic analysis BAL proteins was performed. Proteomic...
Abstract Objective Anemia of chronic disease is a frequent consequence in rheumatoid arthritis and associated with major clinical patient outcomes. The present cross-sectional study explored the role hepcidin (HEP) anemia by studying its relationships markers anemia, iron metabolism, inflammation, erythropoiesis. Methods Blood samples from anemic (n = 43) nonanemic patients were analyzed for (hemoglobin, mean corpuscular volume, hemoglobin, hemoglobin concentration, red cells distribution...
Ioannina University Hospital, Ioannina, Greece.To evaluate the value of adding an interferon-gamma release assay (IGRA) to tuberculin skin test (TST) for detecting latent tuberculous infection (LTBI) in a Greek university hospital among health care workers (HCWs) predominantly vaccinated with bacille Calmette-Guérin (BCG).Of 788 HCWs enrolled, 68.1% were BCG-vaccinated. A TST ⩾ 10 mm was considered positive and followed by QuantiFERON-TB(®) Gold In-Tube (QFT-GIT) two-step strategy.Of...
<h3>Background</h3> Rheumatoid arthritis (RA) is characterized by antibodies to citrullinated protein antigens (ACPA). Porphyromonas gingivalis (PG) a major pathogen in periodontitis which possesses enzyme, peptidylarginine deiminase with the potential generate leading autoimmune response. <h3>Objectives</h3> The aim of study was examine existence PG patients RA. <h3>Methods</h3> Antibodies were measured using ELISA as previously described.<sup>1</sup> Thus, Dynatech Immunolon IB microtitre...
Introduction Treatment resistant schizophrenia (TRS) affects at least 15-20% of newly diagnosed patients with schizophrenia. Clozapine treatment for this sub-group should be considered immediately after the failure in response to two antipsychotics (usually risperidone and olanzapine) received adequate doses time. Immune changes have been reported first episode psychosis, although results from various studies remain inconclusive. Very few investigated so far cytokine adipokine TRS....
Introduction An increasing body of evidence suggests that antipsychotic medication can cause immunological changes could be attributed to the amelioration psychotic symptoms or metabolic side effects drugs. So far, results studies remain controversial. Objective Our aim was compare levels interleukin (IL) IL-2, IL-6 and transforming growth factor-β2 (TGF-β2) in drug-naïve, first-episode patients with psychosis before after six weeks medication. Methods Thirty-nine first episode were enrolled...
<h3>Background</h3> Patients with systemic rheumatic diseases have increased prevalence of sensorineural hearing loss (SNHL). Detection cochlin specific antibodies has been reported in patients idiopatic loss. Interestingly, shown a stronger link to autoimmune <h3>Objectives</h3> Objective this cross-sectional study was calculate the SNHL and detect human their sera. <h3>Methods</h3> This prospective study. older that 18 year old who gave informed consent fulfilled criteria American College...
<h3>Background</h3> Systemic lupus erythematosus (SLE) is a chronic autoimmune disease where interferon (IFN) α, considered to play central role in its pathogenesis Anaemia of (ACD) SLE common. Hepcidin may contribute anaemia by limiting iron availability for erythropoiesis. <h3>Objectives</h3> The aim the study was evaluate INF-α and hepcidin levels sera anaemic non-anaemic patients. <h3>Methods</h3> This pilot patients with established disease. Patients were divided as non- according...