A5090733095- Biopolymer Synthesis and Applications
- Enzyme Structure and Function
- Probiotics and Fermented Foods
- Retinal Development and Disorders
- Nonmelanoma Skin Cancer Studies
- Hidradenitis Suppurativa and Treatments
- Developmental Biology and Gene Regulation
- Connexins and lens biology
- Childhood Cancer Survivors' Quality of Life
- Chemotherapy-related skin toxicity
- Acne and Rosacea Treatments and Effects
- RNA and protein synthesis mechanisms
- Contact Dermatitis and Allergies
- Medical Malpractice and Liability Issues
- Ethics and Legal Issues in Pediatric Healthcare
- Liver Diseases and Immunity
- Cutaneous Melanoma Detection and Management
- Biofuel production and bioconversion
- Neuroscience and Neuropharmacology Research
- Cytokine Signaling Pathways and Interactions
- Colorectal and Anal Carcinomas
- Adolescent and Pediatric Healthcare
- Metal and Thin Film Mechanics
- Morinda citrifolia extract uses
- Diversity and Career in Medicine
University of British Columbia
2021-2025
University of Toronto
1990-2020
The Scarborough Hospital
2020
Office of Science
2010
Center for Devices and Radiological Health
2010
Johns Hopkins University
1998-2005
United States Food and Drug Administration
2005
University of Coimbra
2005
Johns Hopkins Medicine
1998-2002
Nanophthalmos is a rare disorder of eye development characterized by extreme hyperopia (farsightedness), with refractive error in the range +8.00 to +25.00 diopters. Because cornea and lens are normal size shape, occurs because insufficient growth along visual axis places these lensing components too close retina. Nanophthalmic eyes show considerable thickening both choroidal vascular bed scleral coat, which provide nutritive structural support for Thickening tissues general feature axial...
Vertebrate eye development begins at the gastrula stage, when a region known as field acquires capacity to generate retina and lens. Optx2 , homeobox gene of sine oculis-Six family, is selectively expressed in this early later lens placode optic vesicle. The distal ventral portion vesicle are fated become nerve, whereas dorsal eventually loses its neural characteristics activates synthesis melanin, forming retinal pigment epithelium. expression turned off future epithelium but remains...
The susceptibility of newborn mice to the inception tolerance after exposure antigen is associated with their deficiency in production endogenous interleukin 2 (IL-2). As further evidence complicity IL-2 and maintenance tolerance, it shown here that a solid long-lasting state induced by intravenous injection into CBA lymphoid cells from (CBA X C57BL/10ScSn)F1 hybrids can be brought an end administration exogenous or supplementing otherwise normal diet vitamin A acetate, effect which increase...
Optx2, a member of the sine oculis-Six family homeobox genes, is first expressed in anterior neural plate mouse embryo, and subsequently optic vesicle ventral forebrain. During later development, expression further restricted to precursors retina, chiasm, adenohypophysis neurohypophysis. In adult Optx2 mRNA found cells within ganglion cell layer inner nuclear layer.
A genomic library of Lactobacillus casei DNA containing 10,000 individual clones was constructed in the plasmid pUC13. The gene encoding L. folylpolyglutamate synthetase isolated from by complementation a folC mutant Escherichia coli. expressed E. coli its own promoter and produced amplified activity with properties identical those purified enzyme. absence dihydrofolate preferential utilization 5,10-methylenetetrahydrofolate, rather than 10-formyltetrahydrofolate as folate substrate,...
While admitted to the hospital for metastatic rectal cancer, a woman in her 40s with Fitzpatrick skin type II presented two-day history of well-demarcated, tender erythematous patches fine scales over dorsal aspects arms ([figure 1][1]). She was systemically well. For
Abstract Acne occurs in up to 90% of young adolescents, but prior research has found that this population exhibits a limited understanding acne and is vulnerable myths misinformation accumulated from family members, friends, social media. We created virtual presentation on skin hygiene, prevention, acne‐associated stigma for adolescent youth (aged 9–13) improve health literacy, which was reviewed by three board‐certified dermatologists. A descriptive cross‐sectional study using data...
Abstract The acquisition of active avoidance (AA) behavior is typically aided by the presence two signals—the warning signal, which predicts future occurrence an aversive event (e.g., shocks), and safety presented upon successful oncoming shocks. While signal could be conceived to act as a Pavlovian fear cue, likely mediated brain areas that underlie cue conditioning, neural substrates underlying signaling are less clear, largely due unavailability AA tasks devoid explicit signal. present...
The DNA sequence of the valS gene from Lactobacillus casei and predicted amino acid its valyl-tRNA synthetase product have been determined. An open reading frame coding for a protein 901 acids was found. A clone containing intact L. functionally complemented temperature-sensitive growth mutant strain 236c Escherichia coli. downstream folylpolyglutamate are transcribed in same direction but separated by putative transcription terminator.