A5040447631- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Bacterial Identification and Susceptibility Testing
- Traumatic Brain Injury and Neurovascular Disturbances
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Venous Thromboembolism Diagnosis and Management
- Healthcare professionals’ stress and burnout
- Muscle and Compartmental Disorders
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Emergency and Acute Care Studies
- Phonocardiography and Auscultation Techniques
- Ultrasound in Clinical Applications
- Anesthesia and Neurotoxicity Research
- Respiratory Support and Mechanisms
- Musculoskeletal pain and rehabilitation
- Travel-related health issues
- Disaster Response and Management
- Poisoning and overdose treatments
- Anesthesia and Sedative Agents
- Noise Effects and Management
- Blood transfusion and management
Hôpital d'instruction des Armées Percy
2012-2024
Université Paris-Saclay
2024
Service de Santé des Armées
2024
Université Paris Cité
2018-2022
Institut de Médecine Tropicale du Service de Santé des Armées
2022
Hôpital Lariboisière
2020
Hypertension pulmonaire : physiopathologie et innovation thérapeutique
2020
Centre Chirurgical Marie Lannelongue
2020
Assistance Publique – Hôpitaux de Paris
2018
Délégation Paris 6
2014-2017
Objective: Early identification of causative microorganism(s) in patients with severe infection is crucial to optimize antimicrobial use and patient survival. However, current culture-based pathogen slow unreliable such that broad-spectrum antibiotics are often used insure coverage all potential organisms, carrying risks overtreatment, toxicity, selection multidrug-resistant bacteria. We compared the results obtained using a novel, culture-independent polymerase chain reaction/electrospray...
Herpes viruses can be reactivated among immunocompetent patients in intensive care unit (ICU). Cytomegalovirus (CMV) and herpes simplex virus (HSV) have been the most studied. We hypothesized that Epstein-Barr (EBV) could also during their stay ICU this would associated with morbidity mortality.This prospective observational study included 90 an of ≥ 5 days. CMV HSV were considered when clinically suspected DNA was researched blood or bronchoalveolar lavage (BAL). EBV viral quantification...
Three patients with extensive necrotizing pneumonia due to Panton-Valentine leukocidin-positive Staphylococcus aureus strains and aggravating factors (leukopenia count of less than 3x10(9)/liter in all three cases hemoptysis two cases) were successfully treated toxin-suppressing agents introduced rapidly after hospital admission.
Closed-loop resuscitation can improve personalization of care, decrease workload and bring expert knowledge in isolated areas. We have developed a new device to control the administration fluid or simultaneous co-administration norepinephrine using arterial pressure.We evaluated performance our prototype rodent model haemorrhagic shock. After shock, rats were randomized five experimental groups: three resuscitated with two norepinephrine. Among groups fluid, one was by physician according...
Ventilation of Acute Respiratory Distress Syndrome (ARDS) is a challenge, and there definitely need for lack variations between delivered set tidal volume (Vt). We have assessed the ability ventilator T-birdVS02 LTV-1000 to deliver lung model with ARDS Vt at different simulated altitudes.We used decompression chamber mimic hypobaric environment range cabin altitudes 1,500, 2,500, 3,000 m (4,000, 6,670, 8,000 feet, respectively). Ventilators were tested realistic parameters. was 400 mL 250 in...
Rationale: Norepinephrine (NE) is commonly used in combination with fluid during resuscitation of hemorrhagic shock, but its impact on kidney microcirculation, oxygenation, and function still unknown this setting. Objectives: During shock resuscitation, does a NE affect oxygenation tension, microcirculatory perfusion, 48-hour function, as compared alone? Methods: Hemorrhagic was induced 24 pigs, 8 pigs were included sham group. Resuscitation performed, using closed-loop device, either by...
Hemorrhagic shock is the leading cause of preventable early death in trauma patients. Transfusion management guided by international guidelines promoting and aggressive transfusion strategies. This study aimed to describe timelines a center identify key points performing efficient transfusions.This monocentric retrospective 108 severe patients, transfused within first 48 h hospitalized an intensive care unit between January 2017 May 2019.One hundred eight patients were with 1250 labile blood...
Background Hemorrhagic shock (HS) and rhabdomyolysis (RM) are two important risk factors for acute kidney injury after severe trauma; however, the effects of combination RM HS on function unknown. The purpose this study was to determine impact renal function, oxygenation, perfusion, morphology in a pig model. Methods Forty-seven female pigs were divided into five groups: sham, RM, HS, moderate (RM4/HS), (RM8/HS). Rhabdomyolysis induced by intramuscular injection glycerol 50% with dose (4...