Mathieu Boutonnet

ORCID: 0000-0002-7334-0132
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About
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Research Areas
  • Trauma and Emergency Care Studies
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Disaster Response and Management
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Airway Management and Intubation Techniques
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Hemodynamic Monitoring and Therapy
  • Emergency and Acute Care Studies
  • Travel-related health issues
  • Respiratory Support and Mechanisms
  • Trauma Management and Diagnosis
  • Pelvic and Acetabular Injuries
  • Abdominal Trauma and Injuries
  • Simulation-Based Education in Healthcare
  • Sepsis Diagnosis and Treatment
  • Blood transfusion and management
  • Traumatic Ocular and Foreign Body Injuries
  • COVID-19 and healthcare impacts
  • Tracheal and airway disorders
  • Climate Change and Health Impacts
  • Venous Thromboembolism Diagnosis and Management
  • Anesthesia and Sedative Agents
  • Health and Conflict Studies
  • Foreign Body Medical Cases

Hôpital d'instruction des Armées Percy
2016-2025

Prince Medical (France)
2021-2024

HIA du Val-de-Grâce à Paris
2011-2024

Service de Santé des Armées
2016-2024

Assistance Publique – Hôpitaux de Paris
2020-2022

Centre Hospitalier Universitaire de Reims
2022

Hôpitaux Universitaires de Strasbourg
2022

Hôpitaux Universitaires Henri-Mondor
2022

Aix-Marseille Université
2022

Université de Reims Champagne-Ardenne
2022

Haemorrhagic shock is the leading cause of early preventable death in severe trauma. Delayed treatment a recognized prognostic factor that can be prevented by efficient organization care. This study aimed to develop and validate Red Flag, binary alert identifying blunt trauma patients with high risk haemorrhage (SH), used pre-hospital team order trigger an adequate intra-hospital standardized control response: massive transfusion protocol and/or immediate haemostatic procedures.A multicentre...

10.1186/s13054-018-2026-9 article EN cc-by Critical Care 2018-05-02

To update the French guidelines on management of trauma patients with spinal cord injury or suspected injury. A consensus committee 27 experts was formed. formal conflict-of-interest (COI) policy developed at outset process and enforced throughout. The entire conducted independently any industrial funding (i.e. pharmaceutical, medical devices). authors were advised to follow rules Grading Recommendations Assessment, Development Evaluation (GRADE®) system guide assessment quality evidence....

10.1016/j.accpm.2020.02.003 article EN cc-by Anaesthesia Critical Care & Pain Medicine 2020-03-27

Abstract Background Trauma-induced coagulopathy includes thrombocytopenia and platelet dysfunction that impact patient outcome. Nevertheless, the role of transfusion remains poorly defined. The aim study was 1/ to evaluate early on 24-h all-cause mortality 2/ describe count at admission (PCA) its relationship with trauma severity Methods Observational carried out a multicentre prospective registry. All adult patients directly admitted in participating centres between May 2011 June 2019 were...

10.1186/s13054-022-03928-y article EN cc-by Critical Care 2022-02-21

‘ We are at war ’, French President Emmanuel Macron said in an address to the nation on 16 March 2020. As part of this national effort, Military Medical Service (FMMS) is committed fight against COVID-19. This original report aimed describe and detail actions that FMMS has carried out nationwide COVID-19 pandemic France, as well overseas. Experts field reported major conducted by during France. In just few weeks, developed ad hoc medical capabilities support health authorities. It...

10.1136/bmjmilitary-2020-001569 article EN BMJ Military Health 2020-08-05

The French Military Health Service has standardized its military prehospital care policy in a ''Sauvetage au Combat'' (SC) program (Forward Combat Casualty Care). A major part of the SC training relies on simulations, which are challenging and costly when dealing with more than 80,000 soldiers. In 2014, decided to develop deploy 3D-SC1, serious game (SG) intended train assess soldiers managing early steps SC.The purpose this paper is describe creation production 3D-SC1 present deployment.A...

10.2196/games.5340 article EN cc-by JMIR Serious Games 2016-05-18

The first wave of the COVID-19 pandemic confronted healthcare systems around world with unprecedented organizational challenges, particularly regarding availability intensive care unit (ICU) beds. One strategy implemented in France to alleviate pressure during was inter-hospital transfers selected ICU patients from overwhelmed areas towards less saturated ones. At time, impact this transfer on patient mortality unknown. We aimed compare in-hospital rates among who were transferred another...

10.1186/s13613-021-00933-2 article EN cc-by Annals of Intensive Care 2021-10-26

Abstract Background Rapid referral of traumatic brain injury (TBI) patients requiring emergency neurosurgery to a specialized trauma center can significantly reduce morbidity and mortality. Currently, no model has been reported predict the need for acute in severe moderate TBI patients. This study aims evaluate performance Machine Learning-based models establish procedure within 24 h after TBI. Methods Retrospective multicenter cohort using data from national registry (Traumabase®) November...

10.1186/s13017-022-00449-5 article EN cc-by World Journal of Emergency Surgery 2022-08-03

Importance Hemorrhagic shock is a common cause of preventable death after injury. Vasopressor administration for patients with blunt trauma and hemorrhagic often discouraged. Objective To evaluate the association early norepinephrine 24-hour mortality among shock. Design, Setting, Participants This retrospective, multicenter, observational cohort study used data from 3 registries in US France on all consecutive January 1, 2013, to December 31, 2018. Patients were alive admission shock,...

10.1001/jamanetworkopen.2022.34258 article EN cc-by-nc-nd JAMA Network Open 2022-10-07

Blunt traumatic aortic injury (BTAI) in severe trauma patients is rare but potentially lethal. The aim of this work was to perform a current epidemiological analysis the clinical and surgical management these European country.This multicentre, retrospective study using prospectively collected data from French National Trauma Registry Uniform Hospital Discharge Database 10 centres France. primary endpoint prevalence BTAI. secondary endpoints focused chronologically on characteristics,...

10.1016/j.ejvs.2021.09.043 article EN cc-by-nc-nd European Journal of Vascular and Endovascular Surgery 2022-02-08

To reduce the number of deaths caused by exsanguination, initial management severe trauma aims to prevent, if not limit, lethal triad, which consists acidosis, coagulopathy, and hypothermia. Recently, several studies have suggested adding hypocalcemia triad form diamond, but evidence supporting this change is limited. Therefore, aim study was compare diamond for their respective associations with 24-h mortality in patients receiving transfusion. We performed a multicenter retrospective...

10.1186/s13017-024-00572-5 article EN cc-by-nc-nd World Journal of Emergency Surgery 2025-01-07

Background Ventilator-associated pneumonia (VAP) is the most common infection in severely injured patients requiring mechanical ventilation. Chest trauma has been identified as a significant risk factor for VAP. This study aimed to describe factors early VAP with severe blunt thoracic admitted intensive care unit (ICU) and receiving Materials Methods A retrospective cohort was conducted using data from national registry including 17 French centers during period of seven years. The included...

10.1371/journal.pone.0324120 article EN cc-by PLoS ONE 2025-05-27

Tranexamic acid (TXA) use in severe trauma remains controversial notably because of concerns the applicability CRASH-2 study findings mature systems. The aim our was to evaluate outcomes TXA administration severely injured patients managed a care system.We performed retrospective data prospectively collected TraumaBase registry (a regional collecting prehospital and hospital admitted six Level I centers Paris Area, France). In mortality compared between having received or not early phase...

10.1097/ta.0000000000001880 article EN Journal of Trauma and Acute Care Surgery 2018-03-14

Fibrinogen concentrate is widely used in traumatic hemorrhagic shock despite weak evidence the literature. The aim of study was to evaluate effect fibrinogen administration within first 6 hours on 24-hour all-cause mortality using a causal inference approach.Observational from French multicenter prospective trauma registry performed. Hemorrhagic defined as transfusion four or more red blood cell units after admission. confounding variables for outcome (24-hour mortality) and treatment...

10.1097/ta.0000000000002624 article EN Journal of Trauma and Acute Care Surgery 2020-02-17

Abstract Background Emerging evidence suggests that the reallocation of health care resources during COVID-19 pandemic negatively impacts system. This study describes epidemiology and outcome major trauma patients admitted to centers in France first wave outbreak. Methods retrospective observational included all consecutive aged 15 years older into contributing TraumaBase® registry SARS-CoV-2 France. cohort was compared historical cohorts (2017–2019). Results Over a 4 years-study period,...

10.1186/s13049-021-00864-8 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2021-03-22

BACKGROUND The epidemiology of French military severe trauma patients injured during recent operations remains poorly described, even if operations, casualties sustained, and care rendered in a different system are distinct from others. This study aimed at describing the characteristics these upon arrival hospital France stay. METHODS 5-year retrospective cohort included all servicemen admitted to intensive unit. Data on Percy stay were obtained national civilian registry. RESULTS Of 1,990...

10.1097/ta.0000000000004034 article EN Journal of Trauma and Acute Care Surgery 2023-05-09
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