A5025220431- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Cannabis and Cannabinoid Research
- Olfactory and Sensory Function Studies
- Evolutionary Psychology and Human Behavior
- Zebrafish Biomedical Research Applications
- Functional Brain Connectivity Studies
- Memory and Neural Mechanisms
Boston College
2017-2021
The ability of an individual to reduce the intensity, duration or frequency a stressor is critical determinant consequences that on physiology and behavior. To expand our understanding brain networks engaged during controllable uncontrollable stress identify sex differences, we used functional connectivity analyses immediate early gene product Fos in male female rats exposed either tail shocks. Twenty-eight regions interest (ROI) were selected from structures previously evinced be...
Oxytocin (OT) often regulates social behaviours in sex-specific ways, and this may be a result of sex differences the brain OT system. Adult male rats show higher receptor (OTR) binding posterior bed nucleus stria terminalis (pBNST) than adult female rats. In present study, we investigated mechanisms that lead to difference. First, found have OTR mRNA expression pBNST females at postnatal day (P) 35 P60, which demonstrates presence difference density message level. Second, was absent P0 P3,...
Abstract The description and quantification of social behavior in laboratory rodents is central to basic translational research. Conventional ethological approaches are fraught with challenges including bias, significant human effort temporal accuracy. Here we show proof principle that machine learning can be applied tests decision making. Rats underwent novelty preference which were scored both by hand again a convolutional neural network generated the DeepLabCut computer vision package...