- Colorectal Cancer Treatments and Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Chronic Lymphocytic Leukemia Research
- Pharmacological Effects of Natural Compounds
- Sports injuries and prevention
- Bone fractures and treatments
- Metastasis and carcinoma case studies
- Toxin Mechanisms and Immunotoxins
- Immunotherapy and Immune Responses
- Knee injuries and reconstruction techniques
- Lung Cancer Research Studies
- Chemotherapy-related skin toxicity
- Cancer Mechanisms and Therapy
- Chemotherapy-induced cardiotoxicity and mitigation
- Biomedical Ethics and Regulation
- Viral-associated cancers and disorders
- Orthopedic Infections and Treatments
- Immune Cell Function and Interaction
- Plant Disease Resistance and Genetics
- Acute Lymphoblastic Leukemia research
- Hepatitis B Virus Studies
Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo
2025
University of Turin
2023-2024
CTO Hospital
2024
Azienda Ospedaliera G.Rummo
2016
Ospedale D. Cotugno
2007-2012
University of Naples Federico II
1994-2007
Azienda Ospedaliero Universitaria Ospedali Riuniti
2007
Azienda Ospedaliera di Cosenza
2002-2006
Patients with advanced non-small-cell lung cancer (NSCLC) treated immune checkpoint blockers (ICBs) ultimately progress either rapidly (primary resistance) or after durable benefit (secondary resistance). The vaccine OSE2101 may invigorate antitumor-specific responses ICB failure. objective of ATALANTE-1 was to evaluate its efficacy and safety in these patients. a two-step open-label study the compared standard-of-care (SoC) chemotherapy (CT). human leukocyte antigen (HLA)-A2-positive NSCLC...
Treatment of patients affected by metastatic gastric cancer with low performance status (PS) is a very hard choice. It mandatory to define well-tolerated schedule be employed in these subgroup patients.From June 1999 December 2001, 21 (pts) (> or = 2 ECOG) were treated bimonthly "de Gramont" schedule. was planned perform 6 courses chemotherapy for each patient plus other 2-4 if response had been documented.A total 161 de Gramont administered the pts enrolled. We observed 8 PD (38%), SD 5...
Background/Objectives: Tibial plateau fractures (TPFs) are commonly associated with complex patterns requiring advanced surgical strategies. High-energy trauma often results in severe soft tissue damage, complicating outcomes. Despite advancements management, postoperative complications such as site infections (SSIs) remain prevalent, rates ranging from 9.9% to 30%. This study aims analyze risk factors and approaches influencing acute SSIs following TPF fixation. Methods: A retrospective...
AIM:To improve the results of New therapeutic strategies in hepatocellular carcinoma (HCC).We have conducted a phase Ⅱ study with pegylated liposomal doxorubicin (PLD), 5-fluorouracil (5FU) and folinic acid (FA).METHODS: Thirty-one patients hystologicallyconfirmed, inoperable HCC, received combination c h e m o t ra p y w i P L D 2 5 g / q n d 1 , F U 1200 mg/mq 48 continuous infusion, oral FA 30 mg on every 3 wk until disease progression or intolerable toxicity. RESULTS:The median age was...
Hepatocellular carcinoma (HCC) on liver cirrhosis (LC) is a neoplasm with poor prognosis. Only 10-36% of patients have resectable tumors at presentation, systemic chemotherapy seldom useful and loco-regional treatments are feasible only in selected cases. On the basis possible role depression immune function pathogenesis HCC LC, we employed thymostimulin treatment unresectable aim influencing course disease. Forty-six consecutive were enrolled from January 1987 to December 1993. All...
Summary. Ten patients with aggressive NHL who failed to achieve a complete remission first‐line chemotherapy were treated Ara‐C and αIFN. was administered subcutaneously at 100mg on day 1, 150mg 2 200 mg days 3,4 5 of 28 d cycle; αIFN given 3 million International Units three times week continued for years in CR patients. Six attained median duration 36+ months. Toxicity mild. A new approach second‐line therapy is proposed.
The purpose of this paper is to provide a complete Technical Note for our treatment choice recurrent patellar dislocation in cases trochlear dysplasia, especially patients with types B and D dysplasia according the Dejour classification. Different surgical procedures have been reported instability. One most important anatomic factors address when treating patella dysplasia. Few open trochleoplasty classically described treat dysplastic trochlea. However, recent years, arthroscopic techniques...
Tibial plateau fractures (TPFs) are usually associated with ligamentous or meniscal injuries that could remain misdiagnosed. An appropriate and early recognition may change the surgical management of these soft tissue (STIs) be addressed concomitantly TPF treatment. Magnetic resonance imaging (MRI) is an efficient diagnostic test to identify all STIs in TPFs. This study aims analyze MRI impact identifying guiding treatment
Aim of the study was to improve cure rate and survival aggressive non-Hodgkin's lymphoma (NHL) with a tailored program therapy based on histologic type, prognostic characteristics patients response therapy, use differentiating or cytostatic agents such as Ara-C at low doses alphaIFN. Fifty-four consecutive NHL were treated in induction phase 4 sequential courses third generation regimen (modified CODBLAM IV), followed responsive by 1 cycle doxorubicin cyclophosphamide high dose methotrexate...