A5065209950- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- SARS-CoV-2 and COVID-19 Research
- Electrolyte and hormonal disorders
- Poisoning and overdose treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Influenza Virus Research Studies
- Respiratory Support and Mechanisms
- Mechanical Circulatory Support Devices
- Sepsis Diagnosis and Treatment
- Respiratory viral infections research
City Clinical Hospital
2022-2024
The aim of the study was to assess effect hemoadsorption with CytoSorb on inflammatory response, respiratory failure, and mortality in patients severe novel coronavirus infection. Materials methods. A retrospective single-center cohort comparative hemoadsorbtion using therapy included data from 124 COVID-19 ICU patients. Patients were divided into two groups: arm (group 1, N =93) control without 2, =31). group 1 had more failure at baseline, but otherwise comparable 2 terms clinical...
Introduction. Cytokine storm substantially complicates the clinical course of COVID-19 disease and can potentially lead to multiorgan failure. At present, there are two groups cytokine control treatment methods extensively described in literature: pharmacological approach extracorporeal techniques. Pharmacological is most often either use tocilizumab-induced interleukin receptor blockade or suppress inflammatory mediators’ production with glucocorticosteriods. Materials methods. We have...
Comparative analysis of the results clinical-laboratory and instrumental data from 379 patients hospitalized during 2009—2016, with influenza complicated pneumonia, showed that most severe lung lesions were statistically significantly more likely to develop in first three days caused by shift changed agent comorbid diseases — chronic heart vessels (in isolation or association other factors). The differences main characteristics pneumonia patterns cytokine responses between survivors deceased...
Introduction. Glucocorticoids are used worldwide to control hyperinflammation in hospitalized COVID‑19 patients. Nevertheless, the debate on appropriate initiation time, effective treatment duration and modes of administration is still ongoing. The aim this retrospective group analysis was evaluate influence early methylprednisolone (MP) mode acute respiratory distress syndrome (ARDS) dynamics patients with COVID‑19. Materials methods. We performed a 61 patients, who received MP infection...
We present a case of mechanical hemolysis as complication extracorporeal membrane oxygenation (ECMO) occurring in COVID-19 patient result pump head thrombosis. After emergency circuit replacement, hemoadsorption was initiated to address the negative effects and plasma free hemoglobin rise setting rapid clinical deterioration impaired renal function. During therapy severity reduced, lactate dehydrogenase (LDH) levels decreased, while P/F ratio increased two-fold. The discharged from hospital...
Introduction. Hormones are traditionally not recommended in the presence of bacterial infection, as such use may lead septic complications. However, we have found that early low to medium methylprednisolone doses a specific administration mode developed on basis scientific publications and our own data stop ARDS progression hospitalized patients with COVID-19 associated pneumonia without complicating process. The article looks into effects used ‘bolus followed by continuous infusion’ within...