A5101805031- Anorectal Disease Treatments and Outcomes
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Advanced Breast Cancer Therapies
- Immunodeficiency and Autoimmune Disorders
- Diverticular Disease and Complications
- Metastasis and carcinoma case studies
- Colorectal Cancer Surgical Treatments
- Helicobacter pylori-related gastroenterology studies
- Stoma care and complications
- Alcohol Consumption and Health Effects
- Liver Disease Diagnosis and Treatment
- Inflammatory Bowel Disease
- Cancer-related Molecular Pathways
- Pelvic floor disorders treatments
- Esophageal Cancer Research and Treatment
- Education and Work Dynamics
- Neuroendocrine Tumor Research Advances
- Palliative Care and End-of-Life Issues
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Gout, Hyperuricemia, Uric Acid
- Hepatitis B Virus Studies
- Thyroid Cancer Diagnosis and Treatment
Qingzhou City People's Hospital
2025
Chengdu University of Traditional Chinese Medicine
2025
Zigong First People's Hospital
2019-2024
Nanjing Medical University
2010-2023
Shandong University
2019-2023
Second Hospital of Shandong University
2022-2023
Second Affiliated Hospital of Zhejiang University
2016-2023
Ningbo No. 2 Hospital
2023
Jiangsu Cancer Hospital
2013-2023
Zhengzhou University
2023
Abstract Early gastric carcinoma (EGC) in Chinese patients remains poorly understood and endoscopic therapy has not been well established. Here, we compared clinicopathologic features between early proximal (PGC, n = 131) distal (DGC, 307) consecutive 438 EGCs diagnosed with the WHO criteria. By endoscopy, PGCs showed protruding elevated patterns 61.9%, while depressed excavated 33.6%, which were significantly different from those (32.6% 64.5%) DGCs. smaller (1.9 cm average, versus 2.2...
Non-alcoholic fatty liver disease (NAFLD) is a common chronic metabolic worldwide. Up to 70%-80% of patients with NAFLD were obese, especially abdominal obesity. Many indicators obesity have been reported, including waist circumference (WC), visceral index (VAI), lipid accumulation (LAP), and Chinese VAI (CVAI). However, few studies investigated the associations between these indices NAFLD. This present study aims explore A total 7,238 participants involved in cross-sectional study, 1,584...
Chronic lymphocytic leukemia (CLL) is the most common in western world. Alterations microRNAs (miRNAs) expression have been proposed to play a role CLL pathogenesis. Dicer and Drosha are main regulators of miRNA biogenesis, deregulation their has indicated as possible cause alterations observed various cancers. To investigate CLL, we assessed correlation with other prognostic factors, including Binet stages, immunoglobulin heavy chain variable gene (IGHV) mutation status, TP53 ZAP-70 protein...
To investigate risk factors of lymph node metastasis (LNM) in Chinese early gastric carcinoma (EGC) patients diagnosed using the World Health Organization (WHO) criteria and compare differences those between proximal (PGC) distal (DGC).Among 3 176 cancer resections we identified 379 (11.9%) consecutive EGC (104 PGC 275 DGC) with lymphadenectomy performed at Affiliated Nanjing Drum Tower Hospital University (Nanjing, Jiangsu Province, China) January 2005 December 2012. Endoscopic...
Purpose: Papillary early gastric carcinoma (EGC) is uncommon but shows worse prognosis in our most recent study a Chinese population with unknown reasons. The aim of the present was to further investigate risk factors for patients papillary adenocarcinoma, compared those tubular adenocarcinoma. Methods: We searched electronic pathology databank radical gastrectomy cases over an 8-year period at single medical center Nanjing, China, and identified consecutive 240 EGC that were classified as...
Complement deficiencies have been identified in many chronic lymphocytic leukemia (CLL) patients. Supplying fresh frozen plasma (FFP)-derived complement can enhance complement-dependent cell lysis by the rituximab. The objective of our study was to evaluate clinical efficacy and safety treatment adding FFP rituximab fludarabine refractory CLL Twenty-two patients were treated with two units followed rituximab, 375 mg/m(2), as a single agent, repeated every 1-2 weeks. Patients received median...
Background: A colostomy can negatively impact patients' quality of life. Recent research findings suggest that self-efficacy and psychosocial adjustment are positively associated with life, but there few reports about the patients a permanent colostomy. Objectives: The objective study was to evaluate effect 3-week Expert Patient Program (EPP) on knowledge, stoma care self-efficacy, self-management, in Chinese who had Methods: Eleven volunteered be trained expert patients. Eighty-one were...
Cholestasis, characterized by impaired bile flow, impacts cognitive function through systemic mechanisms, including inflammation and metabolic dysregulation. Despite its significance, targeted predictive models for impairment in cholestasis remain underexplored. This study addresses this gap developing a machine learning-based model tailored to population. Clinical biochemical data from Qingyang People's Hospital (2021–2023) were used train validate predicting (MoCA ≤ 17). Recursive feature...
Abstract Background The thyroglobulin (Tg)/ thyroid-stimulating hormone (TSH) ratio has manifested to be a reliable marker for predicting prognosis in patients with differentiated thyroid carcinoma (DTC). objective of this study was compare the efficacy Tg and Tg/TSH models successful response radioactive iodine therapy. Methods One thousand six hundred forty-two DTC receiving 131 I radiotherapy were finally enrolled retrospective study. divided into training set ( n = 973) validation 669)...
Abstract A single nucleotide polymorphism (SNP) at position 309 in the promoter region of MDM2 leading to increased expression and attenuated function p53 has recently been suggested as an unfavorable prognostic marker chronic lymphocytic leukemia (CLL) although this questioned. The SNP309 genotypes 173 CLL patients 260 healthy controls were detected by polymerase chain reaction–restriction fragment length (PCR–RFLP) method, which was confirmed direct DNA sequencing. Compared with T/T...
No confirmed risk factors are known to predict Richter syndrome (RS), and the value of clinical prognosticators conventionally applied chronic lymphocytic leukemia (CLL) is not firmly established in this setting. The objective study was present evidence for RS Chinese patients with CLL transformation syndrome. With a median follow-up 43 months from diagnosis 149 patients, 16 (10.7%) progressed diffuse large B-cell lymphoma (DLBCL). According correlation analysis, high level lactate...
Cytogenetic features have an important role in the definition of distinct disease subsets CLL. The deletion 6q is known to occur at a relatively low frequency CLL, and detailed analysis hematologic clinical patients with CLL limited. To verify incidence prognostic significance Chinese fluorescence situ hybridization (FISH) was used 240 del(6q23) found 18 (7.5%), only five had 6q23 as sole abnormality. Strong correlations between parameters were not found. A difference terms survival compared...
Objective The incidence of proximal gastric carcinoma ( PGC ) is rising worldwide for unknown reasons. Herein we compare the risk factors early with distal DGC in patients treated at a single tertiary hospital C hina. Methods Risk 379 consecutive surgically resected EGC diagnosed according to 2010 W orld H ealth O rganization criteria were studied by reviewing their medical records and esophagogastroduodenoscopy/biopsy findings interviewing family members patients' history environmental...
To investigated the effect and mechanism of Fangjihuangqi Tang (FHT) on lower urinary tract dysfunction induced by benign prostatic hyperplasia (BPH) in rats. Male rats were randomly divided into seven groups: normal, model, finasteride (0.5 mg/kg), terazosin FHT (10, 5, 2.5 g/kg). Rats administered testosterone mg sc) for 6 weeks after orchiectomy, excluding normal group. All intragastrically assigned drugs 4 from third week. Urodynamics assessed under anesthesia. Serum dihydrotestosterone...