A5100382718- Ovarian function and disorders
- Hormonal Regulation and Hypertension
- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Reproductive Biology and Fertility
- Diet and metabolism studies
- Ovarian cancer diagnosis and treatment
- Liver Disease Diagnosis and Treatment
- Adrenal Hormones and Disorders
- Adipose Tissue and Metabolism
- Lipid metabolism and disorders
- Radiation Dose and Imaging
- Stress Responses and Cortisol
- Cancer, Hypoxia, and Metabolism
- Growth Hormone and Insulin-like Growth Factors
- Diet, Metabolism, and Disease
- Pancreatic function and diabetes
- Artificial Intelligence in Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Biomarkers in Disease Mechanisms
- Immunotherapy and Immune Responses
First Affiliated Hospital of Bengbu Medical College
2018-2025
Renji Hospital
2006-2024
Shanghai Jiao Tong University
2009-2024
Pratt Institute
2022-2024
Duke University
2018-2024
Shandong University
2020-2023
Chongqing Three Gorges Central Hospital
2022
Affiliated Hospital of Nantong University
2020-2021
Nantong University
2020-2021
Second Affiliated Hospital of Nantong University
2021
Projecting the burden of thyroid cancer (TC) over time provides essential information to effectively plan measures for its management and prevention. This research obtained data from Global Burden Disease (GBD) Study between 1990 2019 model how TC will affect China until 2039 by conducting Bayesian age-period-cohort analysis. The number new cases in was 10,030 1990, 39,080 2019, is projected be 47,820 2039. corresponds 3,320, 7,240, 4,160 deaths, respectively. Disability-adjusted life years...
Polycystic ovary syndrome (PCOS) is a complex showing clinical features of an endocrine/metabolic disorder, including hyperinsulinemia and hyperandrogenism. Polyunsaturated fatty acids (PUFAs) their derivatives, both tightly linked to PCOS obesity, play important roles in inflammation reproduction. This study aimed investigate serum lipid profiles newly diagnosed patients with using lipidomics correlate these the hyperandrogenism associated obesity. Thirty-two women 34 controls were divided...
The antihyperglycemic effects of tea are well documented. However, the fermented on translocation glucose transporter 4 (GLUT4), major for uptake in postprandial period, skeletal muscle and underlying molecular mechanisms not fully understood. This study investigated GLUT4 its related signaling pathways male ICR mice given tea. Intake oolong, black, or pu-erh 7 days enhanced to plasma membrane muscle. Each type stimulated phosphorylation phosphoinositide 3-kinase (PI3K), Akt/protein kinase...
To investigate the associations of dyslipidemia with insulin resistance and β cell function in individuals normal glucose tolerance (NGT) different categories impaired regulation (IGR).544 subjects (365 and/or IGR 179 lipid tolerance) were enrolled study. All underwent oral test (OGTT). HOMA-IR was used to evaluate sensitivity. Disposition index (DI) function. Multiple linear regression analysis performed assess correlations among profiles, function.Among NGT, those had higher level but...
1) Background: Infertility and dyslipidemia are frequently present in both women with polycystic ovary syndrome (PCOS) subjects thyroid dysfunction. Limited study regarding the association between stimulating hormone (TSH) level phenotypes euthyroid PCOS women. We aimed to determine whether variation of TSH associates patients. 2) Methods: Cross-sectional including 600 200 age, body mass index (BMI) autoimmunity-matched Chinese from Renji hospital, Shanghai Jiaotong university during January...
ABSTRACT Aim To investigate the effects of depression on patient activation and summer heat adaptation, considering important contributory factors in older adults with increased cardiovascular health concerns extremely hot days. Design Cross‐sectional study adhering to STROBE guidelines. Methods Between July August 2020, a questionnaire survey was administered 245 at risk diseases rural areas. Data were collected utilising validated reliable tools assess activation, depression, frailty,...
The aim of this study is to investigate the impact bevacizumab intraperitoneal perfusion combined with paclitaxel and platinum-based chemotherapy on serum stromal-derived factor-1α (SDF-1α) chemokine ligand 5 (CXCL-5) levels in patients ovarian cancer after tumor cell debulking surgery. This clinical was conducted a cohort 89 who underwent surgery at our hospital from February 2020 2021. were divided into two groups using random number table: control group (n = 44) received postoperative...
Background Apolipoprotein B/apolipoprotein A-I (ApoB/ApoA-I) ratio is a useful predictor of cardiovascular risk. However, the association between ApoB/ApoA-I and risk type 2 diabetes mellitus (T2DM) still obscure. Aims To investigate associations T2DM pre-diabetes in Chinese population, to assess role gender these associations. Methods A stratified random sampling design was used this cross-sectional study which included 264 men 465 women with normal glucose tolerance (NGT), or T2DM. Serum...
Abstract Background The thyroglobulin (Tg)/ thyroid-stimulating hormone (TSH) ratio has manifested to be a reliable marker for predicting prognosis in patients with differentiated thyroid carcinoma (DTC). objective of this study was compare the efficacy Tg and Tg/TSH models successful response radioactive iodine therapy. Methods One thousand six hundred forty-two DTC receiving 131 I radiotherapy were finally enrolled retrospective study. divided into training set ( n = 973) validation 669)...
Studies found that AGE-RAGE system is closely related to insulin resistance and hyperandrogenemia, which are two core pathophysiological processes in polycystic ovary syndrome (PCOS). This study investigate the relationship among advanced glycation end-products/soluble receptor of end-products (AGEs/sRAGE) anthropometric evaluation, homeostatic model assessment-insulin (HOMA-IR), free androgen index (FAI) reproductive-aged PCOS patients.One hundred forty-eight Chinese women with were...
(1) Background: polycystic ovarian syndrome (PCOS) is a heterogeneous with constellation of cardiometabolic risk factors. We aimed to investigate if the association body fat mass (BFM) and skeletal muscle (SMM) differed in PCOS subtypes. (2) Methods: 401 participants (245 156 controls) were assessed for anthropometric measurements, glucose–lipid profiles, reproductive hormones composition propensity score-matched (PSM) analysis. The score (z score, calculated based on levels obesity...
The aim of the present study was to elucidate association between excessive chronic iodine exposure and risk developing papillary thyroid carcinoma (PTC). demographic information pathological characteristics patients with nodules were retrieved from medical records at Second Hospital Shandong University. A fasting urine specimen collected, creatinine urinary concentration (UIC) determined. water data domicile districts these collated published reports. results revealed that almost half...
The first-line treatment for polycystic ovary syndrome (PCOS) is lifestyle modification. However, it currently unknown whether digital medicine can assist patients with PCOS in maintaining a healthy while alleviating symptoms.
This study investigated serum interleukin-10 (IL-10) levels, changes in peripheral blood CD4+CD25+ regulatory T cell (PBCDT) ratios, and the prognosis of cervical cancer (CC) patients.Seventy patients with CC composed observation group, 70 healthy subjects control group. The PBCDT ratios were calculated. Serum IL-10 levels detected a double antibody sandwich enzyme-linked immunosorbent assay (ELISA).The ratio was higher active [12.16±2.41%] than [6.34±1.05%]. [384±106 pg/ml] [104±50 pg/ml];...
Abstract Background Deterioration of sleep quality has been reported to contribute the incidence diabetes and may be responsible for glycemic status in diabetes. The present study explored relationship between variability patients with type 2 (T2D). Methods We recruited 111 T2D this cross-sectional study. Each patient underwent flash glucose monitoring 14 days obtain parameters, such as standard deviation (SD), coefficient variation (CV), mean amplitude excursions (MAGE), daily differences...
Colorectal cancer liver metastasis (CRLM) is the most common form of metastatic colorectal (CRC), one leading causes deaths. The CRLM microenvironment tends to be more immunosuppressive, making immunotherapy less effective. By transcriptomics analysis, we discovered that small leucine-rich protein 1 (SMLR1) upregulated in CRC metastases compared primary tumors. High SMLR1 expression by associated with poor prognosis. Proteomics analysis and cell retention assay revealed associations between...
Papillary thyroid carcinoma (PTC) is one of the fastest growing endocrine system malignant carcinomas detected over past decade.Unfortunately, more than 25% PTC patients are characterized by their aggressiveness and subsequent metastasis; these characteristics usually indicate poor prognosis.Recently, increasing evidence has suggested that solute carrier (SLC) transporters may play a pivotal role in initiation, invasion metastasis human carcinoma.However, expression clinicopathological...
Background: Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia that characterized by hyperinsulinemia, hypoglycemia, and high autoantibody titer. About 50% patients with IAS have taken medication containing sulfhydryl (-SH) groups. We present case developed after taking clopidogrel, drug an active metabolite contains SH-group. Case report: was suspected in 63-year-old Chinese man because concentrations insulin C-peptide during hypoglycemic episodes, positivity for anti-insulin...