A5100411340- Advanced biosensing and bioanalysis techniques
- Gut microbiota and health
- Probiotics and Fermented Foods
- Ferroelectric and Piezoelectric Materials
- Soil Carbon and Nitrogen Dynamics
- Cancer-related molecular mechanisms research
- Microwave Dielectric Ceramics Synthesis
- Biosensors and Analytical Detection
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Proteins in Food Systems
- Food composition and properties
- Multiferroics and related materials
- Plant tissue culture and regeneration
- Colorectal Cancer Treatments and Studies
- Liver Disease Diagnosis and Treatment
- Crystallization and Solubility Studies
- Enzyme Catalysis and Immobilization
- Gastric Cancer Management and Outcomes
- Bacterial Identification and Susceptibility Testing
- interferon and immune responses
- Advanced Nanomaterials in Catalysis
- Polysaccharides Composition and Applications
- Clay minerals and soil interactions
- Soil and Unsaturated Flow
Jiangnan University
2017-2025
Guizhou University
2022-2025
Yunnan Agricultural University
2013-2025
Beijing University of Chemical Technology
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Qingdao Agricultural University
2022-2024
Shanghai Tenth People's Hospital
2024
Tongji University
2024
Second Affiliated Hospital of Jilin University
2024
Nanjing Agricultural University
2023-2024
Electrocatalytic overall water splitting is a promising approach for hydrogen production, and the rational design of catalyst on atomic level critical decreasing energy barrier in both oxygen evolution reactions (HER/OER). Herein, we report an NiIr single atom alloy loaded NiFe-LDH (NiIrSAA-NiFe-LDH) Ir (IrSAC-NiFe-LDH) splitting. The atoms are found via EXAFS fitting DFT calculations to be located top Fe3+ with Ir–O6 coordination IrSAC-NiFe-LDH. as-prepared NiIrSAA-NiFe-LDH presents...
Surface functionalization of molybdenum disulfide (MoS2) was prepared by a simple reflux reaction between DITG-MoS2 and octa-vinyl polyhedral oligomeric silsesquioxanes (OvlPOSS). The structure OvlPOSS-MoS2 confirmed XRD, FTIR TEM. SEM TEM results fracture surface exhibited that dispersed well in the matrix due to good interfacial interaction functionalized MoS2 PVA. thermogravimetric analysis (TGA) differential scanning calorimetry (DSC) indicated thermal decomposition temperature glass...
Chiral covalent organic frameworks (CCOFs), built by the condensation reactions of building blocks with enantiomeric purity and linking subunits, have emerged as a marvelous category porous crystalline material. In addition to stability good porosity, CCOFs possess remarkable enantioselectivity, which would be exploited for asymmetric catalysis chiral separation. β-cyclodextrin (β-CD) its derivatives, group supramolecules hydrophobic cavity, been widely applied molecular specific...
Breast cancer is a prominent cause of death among women worldwide. Recent studies have demonstrated that artemisinin (ART) displays anti-tumor activity. Using mouse breast model, we investigated the effects ART in vitro and vivo to determine how it influences immune response. We measured proliferation apoptosis 4T1 cells after treatment by MTT assay FACS. To examine vivo, tumor volumes survival rates were tumor-bearing mice. FACS was used frequencies Tregs, MDSCs, CD4+ IFN-γ+ T cells, CTLs...
Lead (Pb) has been suggested as an endocrine-disrupting chemical. However, few studies have investigated the association between chronic Pb exposure and fatty liver disease.We aimed to investigate of with disease whether variations gut microbiota involve in mechanism induced by exposure.We conducted a cross-sectional study 3066 rural participants East China. Blood lead level (BLL) was detected, abdominal ultrasonography used diagnose hepatic steatosis. Both definition non-alcoholic (NAFLD)...
Cisplatin-based chemotherapy remains the primary treatment for unresectable and metastatic muscle-invasive bladder cancers (MIBCs). However, tumors frequently develop chemoresistance. Here, we established a orthotopic MIBC mouse model with gene-edited organoids to recapitulate full course of in patients. We found that partial squamous differentiation, called semi-squamatization, is associated acquired chemoresistance both mice human MIBCs. Multi-omics analyses showed cathepsin H (CTSH)...
Nanocatalytic therapy (NCT) has made great achievements in tumor treatments due to its remarkable enzyme-like activities and high specificity. Nevertheless, the limited types of nanozymes undesirable microenvironments (TME) greatly weaken therapeutic efficiency. Developing a combination integrating NCT other strategies is significance for optimal treatment outcomes. Herein, AuPt-loaded Cu-doped polydopamine nanocomposite (AuPt@Cu-PDA) with multiple was rationally designed, which integrated...
Abstract The electrocatalytic methanol oxidation reaction (MOR) is considered as an effective method to replace oxygen evolution (OER) for efficient hydrogen production. However, the sluggish kinetics and difficulty of breaking C─H bond Ni‐based catalysts limit further application. Herein, three high‐entropy layered double hydroxides (HELHs), namely ZnNiFeCoV‐HELH, ZnNiFeCoCr‐HELH, ZnNiFeCoAl‐HELH (denoted V‐HELH, Cr‐HELH, Al‐HELH, respectively), are successfully synthesized. Among them,...
Recent studies have found that certain urinary proteins can efficiently inhibit stone formation. These discoveries are significant for developing effective therapies disease, but the inhibition mechanism of crystallization remains elusive. In present study, polyaspartic acid (PASP) was employed as a model peptide to investigate effect on and morphological evolution struvite. The results demonstrate selective adsorption/binding PASP onto {010} {101} faces struvite crystals in arrowhead-shaped...
Au nanoparticles (Au NPs) can be self-assembled in a bottom-up orderly manner at the oil–water interface, which is widely used as SERS platforms, but stability of NP interface needs to improved due shaking or shifting and Brownian motion. The DNA structure with unique sequence specificity, excellent programmability, flexible end-group modification capability owns good potential precisely control plasmonic structure's distance. In this study, large area substrate obtained from...
Abstract This study was conducted to improve our understanding of the effect biochar on degradation original soil organic carbon (SOC) and resulting net C sequestration. A 120‐day incubation experiment detect CO 2 evolution from amended with three kinds biochar, namely, rice husk (RH), pecan shell (PS), bamboo (BB), at ratios 0% (as control), 1%, 2%, 5%, as well 100% pure evaluate their priming SOC mineralization. Results showed that cumulative mineralized amounts decreased by 7.95–10.7% 5%...
The versatile synthetic intermediate (2S,4R)-4-hydroxylysine can be produced using l-lysine hydroxylase. However, the wild-type enzyme cannot effectively catalyze C4 hydroxylation of to form product. To overcome this bottleneck, we modified hydroxylase from Niastella koreensis (NkLH4), semirational combinatorial active-site saturation test (CAST). We obtained a highly active mutant MT3 (Q161N/T162A/F178Y/E260D) with 24.97-fold increase kcat/Km, compared (791.33 mM–1 s–1 vs 31.69 s–1)....