Ya‐Wen Chen

ORCID: 0000-0003-3149-9871
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About
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Research Areas
  • Birth, Development, and Health
  • Neonatal Respiratory Health Research
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Diversity and Career in Medicine
  • Orthopedic Infections and Treatments
  • Infant Nutrition and Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Spine and Intervertebral Disc Pathology
  • Liver Disease Diagnosis and Treatment
  • Healthcare Policy and Management
  • Global Cancer Incidence and Screening
  • Hepatitis C virus research
  • Colorectal Cancer Screening and Detection
  • Adipose Tissue and Metabolism
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Thyroid Cancer Diagnosis and Treatment
  • Urinary Tract Infections Management
  • Shoulder Injury and Treatment
  • Interpreting and Communication in Healthcare
  • Global Health Workforce Issues
  • Hormonal Regulation and Hypertension
  • Diabetes Management and Research
  • Spinal Fractures and Fixation Techniques
  • PARP inhibition in cancer therapy

Massachusetts General Hospital
2020-2025

Harvard University
2020-2025

Icahn School of Medicine at Mount Sinai
2022-2025

Shenzhen Zhongshan Urological Hospital
2025

University of Science and Technology of China
2025

Wuhan University
2018-2024

New England Baptist Hospital
2023-2024

University of Massachusetts Chan Medical School
2009-2024

Huazhong University of Science and Technology
2015-2024

Shanghai Jiao Tong University
2009-2024

Retaining female physicians in the academic health care workforce is necessary to serve needs of sociodemographically diverse patient populations.To investigate differences rates leaving academia between male and physicians.This cohort study used Care Compare data from Centers for Medicare & Medicaid Services all who billed teaching hospitals March 2014 December 2019, excluding retired during period. Data were analyzed November 11, 2021, May 24, 2022.Physician gender.The primary outcome was...

10.1001/jamanetworkopen.2023.23872 article EN cc-by-nc-nd JAMA Network Open 2023-07-17

Body mass index (BMI), waist circumference (WC), visceral adiposity (VAI), triglyceride glucose (TyG), TyG-BMI, and TyG-WC have been reported as markers of insulin resistance or type 2 diabetes mellitus (T2DM). However, little is known about the associations between aforementioned risk prediabetes in first-degree relatives (FDRs) T2DM patients. 1544 FDRs patients (635 men 909 women) were enrolled initial cross-sectional study all them finished corresponding examinations. Logistic regression...

10.1186/s12967-016-1020-8 article EN cc-by Journal of Translational Medicine 2016-09-07

To assess the association between timing of surgery relative to development Covid-19 and risks postoperative complications.It is unknown whether patients who recovered from then underwent a major elective operation have an increased risk developing complications.The complications for with undergoing 18 types operations in Research Database was evaluated using multivariable logistic regression. Patients were grouped by time SARS-CoV-2 infection; that is, performed: (1) before January 1, 2020...

10.1097/sla.0000000000005308 article EN Annals of Surgery 2021-11-18

Objective This study was conducted to determine the influence of number CD138 + cells in proliferative endometrium on pregnancy outcomes. Methods retrospective cohort from January August 2018. A total 664 infertile women who were not diagnosed with chronic endometritis (CE) and had received respective antibiotic treatment studied. Immunostaining performed for plasmacyte marker CD138. The CD138+ compared mid-luteal phases same patients without therapy. Infertile separated into three groups...

10.3389/fendo.2024.1437781 article EN cc-by Frontiers in Endocrinology 2025-01-22

Importance Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been increasingly prescribed for weight management in recent years. However, little is known about whether preoperative GLP-1 RA use associated with a greater risk of complications after surgery. Objective To investigate postoperative aspiration pneumonia among patients undergoing common surgical procedures. Design, Setting, and Participants This retrospective cohort study, conducted using MarketScan commercial claims...

10.1001/jamanetworkopen.2025.0081 article EN cc-by-nc-nd JAMA Network Open 2025-03-04

Purpose The purpose of this paper is to explore the factors influencing customers’ willingness participate in virtual brand community’s value co-creation and help companies better operating community. Design/methodology/approach Based on social cognitive theory features community, constructed a model co-creation. Then quantitatively analyzed mediating effect moderating effect. Findings empirical analysis came following conclusions: first, communities, would be influenced by subject factors,...

10.1108/oir-08-2017-0232 article EN Online Information Review 2018-11-22

Bisphenol AF (BPAF) is extensively used as a raw material in industry, resulting its widespread distribution the aqueous environment. However, effect of BPAF on hypothalamic-pituitary-thyroidal (HPT) axis remains unknown. For elucidating disruptive effects thyroid function and expression representative genes along HPT zebrafish (Danio rerio) embryos, whole-body total 3,3′,5-triiodothyronine (TT3), 3,5,3′,5′-tetraiodothyronine (TT4), free (FT3) (FT4) levels were examined following 168 h...

10.3390/ijerph121013069 article EN International Journal of Environmental Research and Public Health 2015-10-16

High turnover among general practitioners (GPs) is a significant challenge in China's efforts to build sustainable, effective primary care system, but little data available help understand and address this issue. The study was aiming at assessing the intention leave their posts sample of GPs investigating associated factors. A cross-sectional survey conducted between December 12, 2014 March 10, 2015 Hubei Province, Central China. total 1016 (response rate, 85.67%) were investigated by using...

10.1186/s12875-018-0752-3 article EN cc-by BMC Family Practice 2018-05-24

Intrahepatic and extrahepatic metastases are common findings in hepatocellular carcinoma (HCC). Insulin-like growth factor 2 (IGF2) expression is frequently induced HCC, serum IGF2 levels correlate with the presence of metastases. Yet, role IGF-induced signaling dissemination HCC remains unclear. We have previously observed elevated tumors metastatic potential an mouse model. Here, we demonstrate that inhibition IGF2, or its receptor IGF1R, impairs migration invasion activities murine cells....

10.1593/neo.09476 article EN cc-by-nc-nd Neoplasia 2009-09-01

To investigate the associations of dyslipidemia with insulin resistance and β cell function in individuals normal glucose tolerance (NGT) different categories impaired regulation (IGR).544 subjects (365 and/or IGR 179 lipid tolerance) were enrolled study. All underwent oral test (OGTT). HOMA-IR was used to evaluate sensitivity. Disposition index (DI) function. Multiple linear regression analysis performed assess correlations among profiles, function.Among NGT, those had higher level but...

10.1371/journal.pone.0172221 article EN cc-by PLoS ONE 2017-02-15

Abstract Background Over 700 donor livers are discarded annually in the United States due to high risk of poor graft function. The objective this study was determine impact using normothermic machine perfusion identify transplantable among those currently discarded. Study Design A series 21 human underwent viability assessment during perfusion. Cross‐sectional analysis Scientific Registry Transplant Recipients database and cost performed extrapolate case national experience. Results were...

10.1111/ctr.14069 article EN Clinical Transplantation 2020-08-29
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