A5101745813- Auditing, Earnings Management, Governance
- Hearing, Cochlea, Tinnitus, Genetics
- Peripheral Artery Disease Management
- Anesthesia and Neurotoxicity Research
- Chromatography in Natural Products
- Diabetes Treatment and Management
- Anesthesia and Pain Management
- Ovarian function and disorders
- Diagnosis and Treatment of Venous Diseases
- Angiogenesis and VEGF in Cancer
- Acupuncture Treatment Research Studies
- Spectroscopy and Chemometric Analyses
- Corporate Finance and Governance
- Diabetic Foot Ulcer Assessment and Management
- Vestibular and auditory disorders
- Neurological Disease Mechanisms and Treatments
- Anesthesia and Sedative Agents
- Higher Education and Teaching Methods
- Financial Markets and Investment Strategies
- Aortic aneurysm repair treatments
- Reproductive Biology and Fertility
- Cancer-related molecular mechanisms research
- Clinical practice guidelines implementation
- Aortic Disease and Treatment Approaches
- Extracellular vesicles in disease
Air Force Medical University
2019-2025
Xiangyang Central Hospital
2022-2025
Shenyang Pharmaceutical University
2025
Renji Hospital
2017-2024
Shanghai Ninth People's Hospital
2021-2024
Shanghai Jiao Tong University
2013-2024
Xijing Hospital
2024
University of South China
2022-2024
Air Force Engineering University
2024
Air Force Institute of Aviation Medicine Affiliated Hospital
2023
Abstract Previous studies on the effect of International Financial Reporting Standards (IFRS) accounting quality often have difficulties to control for confounding factors quality. As a result, observed changes in could not be attributed mainly IFRS. We use unique research setting address this issue by comparing publicly listed companies 15 member states European Union (EU) before and after full adoption IFRS 2005. five indicators as proxies find that majority improved EU. That is, there is...
Critical limb ischemia, the final course of peripheral artery disease, is characterized by an insufficient supply blood flow and excessive oxidative stress. H2 S molecular therapy possesses huge potential for accelerating revascularization scavenging intracellular reactive oxygen species (ROS). Moreover, it found that BMP6 most significantly up-expressed secreted protein-related gene in HUVECs treated with GYY4137, a donor, based on transcriptome analysis. Herein, UIO-66-NH2 @GYY4137@BMP6...
Abstract Background Diabetic limb ischemia is a clinical syndrome and refractory to therapy. Our previous study demonstrated that adipose-derived stem cells (ADSCs) overexpressing glyoxalase-1 (GLO-1) promoted the regeneration of ischemic lower limbs in diabetic mice, but low survival rate, difficulty differentiation, tumorigenicity transplanted restricted its application. Recent studies have found exosomes secreted by ADSCs advantages containing parental beneficial factors exhibiting...
Preclinical studies have suggested that adipose-derived mesenchymal stem cells (ADSCs) transplantation can suppress abdominal aortic inflammation and aneurysm expansion through paracrine factors. Yet, the mechanism of action is not fully understood. In present study, we further examined function ADSC-derived exosomes (ADSC-exos) their microRNA-17-5p (miR-17-5p) on (AAA) progression.ADSC-exos were isolated identified. DiR PKH67 staining used to trace ADSC-exo in vivo vitro. Raw264.7 applied...
Our previous study showed that nuciferine (NF) attenuated non-alcoholic fatty liver disease (NAFLD), which is attributed to a high-fat diet (HFD) through reinforcing intestinal barrier functions, regulating lipid metabolism, and improving inflammation. To clarify whether other mechanisms contribute the anti-NAFLD efficacy of NF, present investigated influence NF on bile acid (BA) metabolism gut microbiota in HFD-fed rats. The data demonstrated changed composition colonic BA, particularly...
This article addresses the challenges of understanding, measuring and explaining political identities in post-1997 Hong Kong. It shows that national local are better conceptualized as two distinct attitudes captured with separate scaled items than opposite poles one attitude measured a single categorical item. approach reveals key shift occurred not identity, but nationalistic sentiments, which have initially increased been on downward trend since 2008. also were perceived robustly...
Abstract Under the slogan of 'weiquan' (defending our rights), homeowners in urban China are increasingly prepared to stand up for their rights ownership, often through non-confrontational actions organized by homeowners' associations (yeweihui). There is also a growing concern need create collective platforms on which can support one another, muster resources against powerful developers and lobby status as legitimate organizations. The activists involved this work well aware its political...
1) Background: Infertility and dyslipidemia are frequently present in both women with polycystic ovary syndrome (PCOS) subjects thyroid dysfunction. Limited study regarding the association between stimulating hormone (TSH) level phenotypes euthyroid PCOS women. We aimed to determine whether variation of TSH associates patients. 2) Methods: Cross-sectional including 600 200 age, body mass index (BMI) autoimmunity-matched Chinese from Renji hospital, Shanghai Jiaotong university during January...
Background Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder associated with multiple metabolic conditions including obesity, insulin resistance, and dyslipidemia. PCOS the most common cause of anovulatory infertility; however, molecular diversity ovarian follicle microenvironment not fully understood. This study aimed to investigate follicular fluid (FF) lipidomic profiles in different phenotypes explore novel lipid biomarkers. Methods A total 25 women 12 without who...
Abstract Hidden hearing loss (HHL) is characterized by normal audiometric thresholds but impaired auditory function, particularly in noisy environments. In vivo, we employed brainstem response (ABR) testing and ribbon synapses counting to assess changes mouse observed the morphology of hair cells through scanning electron microscopy. SRT1720 was administered cochlea via round window injection. vitro, western blot analysis RT‐qPCR were used, Lenti‐shNrf2 used knockdown Nrf2 expression....
Benzodiazepine use disorders (BUDs) have become a public health issue that cannot be ignored. We aimed to demonstrate patients with BUDs might undergo changes in white matter (WM) integrity, which are related impaired cognitive function. used diffusion tensor imaging (DTI), kurtosis (DKI), neurite orientation dispersion and density (NODDI), mean apparent propagator (MAP) observe WM structure from 29 sleep BUD (SDBUD), 33 non-BUD (SDNBUD), 25 healthy participants. also compared the diagnostic...
ABSTRACT A rapid and sensitive ultra‐high performance liquid chromatography–tandem mass spectrometry (UHPLC‐MS/MS) method for the determination of bisoprolol in human plasma was established validated. The sample pretreated by methanol precipitation protein, isotope bisoprolol‐d 5 used as internal standard. chromatographic column ACQUITY UPLC BEH‐C 18 (2.1 × 50 mm, 1.7 μm), with 0.2% formic acid aqueous solution mobile phase gradient elution. electrospray ionization (ESI) source positive ion...
Background Apolipoprotein B/apolipoprotein A-I (ApoB/ApoA-I) ratio is a useful predictor of cardiovascular risk. However, the association between ApoB/ApoA-I and risk type 2 diabetes mellitus (T2DM) still obscure. Aims To investigate associations T2DM pre-diabetes in Chinese population, to assess role gender these associations. Methods A stratified random sampling design was used this cross-sectional study which included 264 men 465 women with normal glucose tolerance (NGT), or T2DM. Serum...
Objective: To establish an animal model of noise-induced hidden hearing loss (NIHHL), evaluate the dynamic changes in cochlear ribbon synapses and hair cell morphology, observe involvement SIRT1/PGC-1α signaling pathway NIHHL. Methods: Male guinea pigs were randomly divided into three groups: control group, noise exposure resveratrol treatment group. Each group was five subgroups: 1 day, week, 2 weeks, month post groups. The experimental groups received stimulation at 105 dB SPL for h....
Objectives: To simulate the growth trend of diabetes mellitus in Chinese population. Methods: The system dynamic modeling methodology was used to establish a population prediction model with or without cardiovascular diseases. Lifestyle therapy and use metformin, acarbose, voglibose were assumed be intervention strategy. outcomes will examined at 5, 15, 30 years after 2020. Results: projected number diabetic China would increase rapidly from 141.65 million 2020 202.84 2050. Diabetic patients...
Abstract Background Iliofemoral deep vein thrombosis (IFDVT) causes severe symptoms and affect the quality of life to a great extent. Endovascular thrombectomy stent implantation have been feasible strategie alleviate signs IFDVT. However, venous in‐stent restenosis (ISR) has become an emerging non‐negligible problem. Methods To evaluate histological characteristics ISR, neointima arterial ISR patients were collected examed. explore effect drug‐coated balloon (DCB) on lesions, we conducted...
We present a framework and empirical evidence to explain why, on average, 11% of listed firms in China received modified audit opinions (MAOs) between 1992 2009. argue that there are two reasons for this phenomenon: strong earnings management incentives lower firms’ financial reporting quality soft budget constraints weaken the information governance roles opinions. find eased after receiving MAOs, which suggests MAOs have limited economic consequences. Further analysis shows phenomenon...