A5100341870- Gallbladder and Bile Duct Disorders
- Pediatric Urology and Nephrology Studies
- Autophagy in Disease and Therapy
- Tracheal and airway disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Lung Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Kidney Stones and Urolithiasis Treatments
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Pancreatic and Hepatic Oncology Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Ferroptosis and cancer prognosis
- Endoplasmic Reticulum Stress and Disease
- Radiomics and Machine Learning in Medical Imaging
- Esophageal Cancer Research and Treatment
- Hepatitis B Virus Studies
- Liver Disease and Transplantation
- Gastrointestinal disorders and treatments
- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Biliary and Gastrointestinal Fistulas
- Cholangiocarcinoma and Gallbladder Cancer Studies
Jiangsu Hengrui Medicine (China)
2025
Monash Medical Centre
2005-2025
University of South China
2025
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2025
University of Auckland
2021-2024
Renmin Hospital of Wuhan University
2021-2024
Chengdu Medical College
2024
Wuhan University
2021-2024
First Affiliated Hospital of Xiamen University
2018-2024
Wuhan Prevention and Treatment Center for Occupational Diseases
2024
To explore characteristics of urinary stone composition in China, and determine the effects gender, age, body mass index (BMI), location, geographical region on composition.We prospectively used Fourier-transform infrared spectroscopy to analyse stones from consecutive patients presenting with new-onset urolithiasis at 46 hospitals seven areas between 1 June 2010 31 May 2015. Chi-squared tests logistic regression analyses were associations BMI, region.The most common constituents were:...
Diabetic heart disease morbidity and mortality is escalating. No specific therapeutics exist mechanistic understanding of diabetic cardiomyopathy etiology lacking. While lipid accumulation a recognized cardiomyocyte phenotype diabetes, less known about glycolytic fuel handling storage. Based on in vitro studies, we postulated the operation an autophagy pathway myocardium for glycogen homeostasis - glycophagy. Here visualize occurrence cardiac glycophagy show that characterized by marked...
Since its introduction more than 15 years ago, the GeoDa software for exploration of spatial data has transitioned from a closed source Windows‐only solution to an open and cross‐platform product that takes on look feel native operating system. This article reports evolution in functionality architecture pays particular attention new implementation as library, libgeoda. through clearly structured API, can be integrated into other environments, such R (rgeoda) Python (pygeoda). integration is...
// Guibin Xu 1, 2, 3, * , Yaodong Jiang 4, Yuansong Xiao 5, Xian-De Liu 6 Fei Yue 3 Wenjiao Li Xun 2 Yongzhong He Xianhan Hai Huang Qi Chen Eric Jonasch Leyuan 7 1 Department of Urology, The Fifth Affiliated Hospital Guangzhou Medical University, Guangzhou, Guangdong Province, 510700, China Center for Innovation and Translation Minimally Invasive Techniques, Institute Biosciences Technology, Texas A&M Health Science Center, Houston, Texas, 77030, USA 4 Nanfang Hospital, Southern 510515, 5...
Abstract The events linking rhinovirus (RV) infection to airway symptoms are poorly understood. virus initially infects epithelium followed by a vigorous inflammatory response that may entail spread of RV from other cells in the wall. However, has fastidious growth characteristics and date reproductive primary than human not been confirmed. Airway fibroblasts adjacent contact with epithelial cells, play key role innate immune responses, participate evolution inflammation. To investigate...
Objective . Comparison of outcomes between RIRS with vacuum-assisted ureteral access sheath (V-UAS) and MPCNL in the treatment renal stone. Materials Methods 28 patients 2-4 cm stone were treated using 14/16 F V-UAS. The compared to those who underwent 16 Amplatz a matched-pair analysis 1 : 2 scenario. Matching criteria included size, location laterality, gender, age, BMI, degree hydronephrosis. Patients’ demographics, perioperative postoperative characteristics, complications, stone-free...
Endoscopic reports are essential for the diagnosis and follow-up of gastrointestinal diseases. This study aimed to construct an intelligent system automatic photo documentation during esophagogastroduodenoscopy (EGD) test its utility in clinical practice.Seven convolutional neural networks trained tested using 210,198 images were integrated endoscopic image reporting (EAIRS). We performance through man-machine comparison at three levels: internal, external, prospective test. Between May 2021...
Prompt diagnosis of early gastric cancer (EGC) is crucial for improving patient survival. However, most previous computer-aided-diagnosis (CAD) systems did not concretize or explain diagnostic theories. We aimed to develop a logical anthropomorphic artificial intelligence (AI) system named ENDOANGEL-LA (logical anthropomorphic) EGCs under magnifying image enhanced endoscopy (M-IEE).We retrospectively collected data 692 patients and 1897 images from Renmin Hospital Wuhan University, Wuhan,...
Benzodiazepine use disorders (BUDs) have become a public health issue that cannot be ignored. We aimed to demonstrate patients with BUDs might undergo changes in white matter (WM) integrity, which are related impaired cognitive function. used diffusion tensor imaging (DTI), kurtosis (DKI), neurite orientation dispersion and density (NODDI), mean apparent propagator (MAP) observe WM structure from 29 sleep BUD (SDBUD), 33 non-BUD (SDNBUD), 25 healthy participants. also compared the diagnostic...
Abstract Prostate cancer is the second most common in men after lung cancer. Androgen receptor (AR) signaling plays a key role development and progression of prostate A number AR-centered therapies have been developed for treatment cancer, such as CYP17A1 inhibitor abiraterone, which blocks androgen synthesis pathway, series second-generation AR antagonists. Unfortunately, resistance mechanisms to these AR-signaling targeted agents usually develop within 18 months treatment, including...
Pulmonary fibrosis has been characterized by abnormal proliferation of fibroblasts and massive deposition the extracellular matrix, which results from a complex interplay chronic injury inflammatory responses. MicroRNA-301a (miR-301a) is activated multiple stimulators, contributing to tumorigenesis autoimmune diseases. This study showed that miR-301a was overexpressed in bleomycin-induced murine model pulmonary patients with idiopathic (IPF). In addition, transforming growth factor β (TGF-β)...
Infection by influenza A virus (IAV) and other viruses causes disease exacerbations in chronic obstructive pulmonary (COPD). Immune responses are blunted COPD, a deficit compounded current standard-of-care glucocorticosteroids (GCS) to further predispose patients life-threatening infections. The immunosuppressive effects of elevated transforming growth factor-beta (TGF-β) COPD may amplify lung inflammation during infections whilst advancing fibrosis. In the study, we investigated potential...
Excessive deposition of extracellular matrix proteins in renal tissues causes fibrosis and function failure. Mammalian cells primarily use the autophagy-lysosome system to degrade misfolded/aggregated dysfunctional organelles. MAP1S is an autophagy activator promotes biogenesis degradation autophagosomes. Previously, we reported that suppresses hepatocellular carcinogenesis a mouse model predicts better prognosis patients suffering from clear cell carcinomas. Furthermore, have characterized...
Endoscopic ultrasonography (EUS) is a key procedure for the diagnosis of biliopancreatic diseases. However, performance among EUS endoscopists varies greatly and leads to blind spots during operation, which can impair health outcomes patients. We previously developed an artificial intelligence (AI) device that accurately identified standard stations significantly reduced difficulty image interpretation. In this study, we updated (named EUS-IREAD) validated its in improving quality...
OBJECTIVE To report our experience of endoscopic incision for obstruction vesico‐ureteric anastomosis (VUA) in transplanted kidneys. PATIENTS AND METHODS Between February 2001 and March 2006, six men two women (mean age 38 years, range 27–57) with VUA their kidneys were treated by percutaneous nephrostomy incision. After the was completely cut, JJ stents placed ureter 4–6 weeks. During follow‐up, serum urea, creatinine uric acid levels measured, urine culture, ultrasound examination washout...
Background Mirizzi syndrome is often difficult to diagnose before surgery, and accompanied by extensive adhesions in the cystohepatic (Calot's) triangle difficulty of separating tissue can lead bile duct injury other intraoperative postoperative complications. The aim this study investigate minimally invasive means treating different types syndrome. Methods Fifty-four patients diagnosed with were enrolled between July 2004 May 2012. diagnosis was further refined according Csendes...
The 320-slice computed tomography (CT) provides three-dimensional and dynamic imaging resulting in the ability to assess motion analysis between two adjacent structures (the fourth dimension). Differential movements would indicate that there is no fixation structures.Eight patients with non-small-cell lung cancers located vital (e.g. great vessels) (n = 4), mediastinum 1) or chest wall 3) where conventional CT was unable exclude local invasion underwent four-dimensional (4D) assessment. In 3...
Abstract Clear cell renal carcinoma (ccRCC) is one of the most common malignant tumors in urinary system. Surgical intervention preferred treatment for ccRCC, but targeted biological therapy required postoperative recurrent or metastatic ccRCC. Autophagy an intracellular degradation system misfolded/aggregated proteins and dysfunctional organelles. Defective autophagy associated with many diseases. Mul1 a mitochondrion‐associated E3 ubiquitin ligase involved regulation divergent...
Vascular participation manifested by a runny nose (rhinorrhea) is prominent feature of the acute consequences rhinovirus infection. endothelial growth factor (VEGF) an angiogenic that also induces potent increases in vascular permeability; it candidate mediator rhinorrhea response to infection as well contributing enhanced leakage rhinovirus-linked asthma exacerbations. It has been shown significant both VEGF protein and mRNA primary airway fibroblasts [Ghildyal et al. (2005): J Med Virol...
When only the TNM classification is used to predict survival in gastric cancer (GC) patients, impact of degree lymphadenectomy on prognosis neglected. This study aimed establish a more effective nomogram based log odds negative lymph nodes/T stage ratio (LONT) surgically treated GC patients.The data resected patients were extracted from Surveillance, Epidemiology, and End Results Program (SEER) database. Univariate multivariate Cox regression analyses identify significant prognostic factors....