A5101972783- Genetically Modified Organisms Research
- CRISPR and Genetic Engineering
- Soybean genetics and cultivation
- Plant Stress Responses and Tolerance
- Banana Cultivation and Research
- Neonatal Respiratory Health Research
- Electrospun Nanofibers in Biomedical Applications
- Wound Healing and Treatments
- Phytochemistry and Biological Activities
- Adipose Tissue and Metabolism
- Inflammatory Bowel Disease
- Lower Extremity Biomechanics and Pathologies
- Biosensors and Analytical Detection
- Animal Genetics and Reproduction
- Migraine and Headache Studies
- Escherichia coli research studies
- Mesenchymal stem cell research
- Plant Molecular Biology Research
- Insect Resistance and Genetics
- Cocoa and Sweet Potato Agronomy
- Legume Nitrogen Fixing Symbiosis
- Plant Toxicity and Pharmacological Properties
- Antimicrobial agents and applications
- Telomeres, Telomerase, and Senescence
- Hearing, Cochlea, Tinnitus, Genetics
Chinese Academy of Sciences
2013-2025
University of Chinese Academy of Sciences
2013-2025
Tianjin Institute of Industrial Biotechnology
2025
Zhengzhou Fruit Research Institute
2025
Chinese Academy of Agricultural Sciences
2025
Beijing Forestry University
2018-2025
Institute of Coal Chemistry
2025
Guangzhou University of Chinese Medicine
2023-2024
Chengdu University of Traditional Chinese Medicine
2023-2024
Tarim University
2024
Skin wounds are usually accompanied by bacterial infections and inflammations, leading to delayed wound healing, which remain a great challenge in clinical treatment. Therefore, it is of significance develop dressings that inhibit accelerate healing. Herein, we reported the fabrication inclusion complex (a β-cyclodextrin covalent organic framework loaded with enrofloxacin flunixin meglumine)-incorporated electrospun thermoplastic polyurethane fibers (named ENR-FM-COF-TPU) via...
Xanthine oxidase (XO), which can catalyze the formation of xanthine or hypoxanthine to uric acid, is most important target gout. To explore conformational changes for inhibitor binding, molecular dockings and dynamics simulations were performed. Docking results indicated that three inhibitors had similar pose binding XO. Molecular showed influenced secondary structure in After inhibitor, peptide Phe798-Leu814 formed different degrees unhelix, while Glu1065-Ser1075, only a partial helix...
High-performance bamboo-based hard carbon is synthesized by controlling the in situ depolymerization and repolymerization of bamboo components.
The cry2Ab and cry3A genes are two of the most important insect-resistant exogenous had been widely used in genetically-modified crops. To develop more effective alternatives for quick identification organisms (GMOs) containing these genes, a rapid visual loop-mediated isothermal amplification (LAMP) method to detect is described this study. LAMP assay can be finished within 60 min at an condition 63 °C. derived products obtained by real-time turbidimeter via monitoring white turbidity or...
<p indent="0mm">Rheumatoid arthritis (RA) is an idiopathic and chronic autoimmune disease for which there are currently no effective treatments. Oxypeucedanin hydrate (OXH) a natural coumarin known its potent anti-inflammatory properties. However, further investigations needed to determine therapeutic efficacy in treating RA. In this study, we evaluate the activity of OXH by LPS-induced RAW264.7 macrophages. Our results show that treatment reverses changes iNOS, COX-2, IL-1β, IL-6, TNF-α...
1. To assess the Inter-rater reliability and test-retest of FPI-6 total score individual scores in static foot posture evaluation among elderly female patients with knee osteoarthritis (KOA), aiming to establish scale. 2. investigate disparity between dominant non-dominant quadriceps characteristics KOA patients, as well explore correlation abnormal posture, thereby offering novel insights for prevention treatment KOA.
Abstract Subclinical hypothyroidism (SCH) is becoming a global health problem due to its increasing prevalence and potential deleterious effects. However, the molecular mechanisms underlying lipid metabolic disorders in SCH have not been fully clarified. Additionally, progress elucidating exact pathogenesis of has hampered by lack optimized mouse models. Methimazole (MMI) was applied construct noninvasive model. Eight-week-old C57BL/6 mice were administrated MMI through drinking water. After...
It is urgently needed to develop novel adjuvants for improving the safety and efficacy of vaccines. Metal-organic frameworks (MOFs), with high surface area, play an important role in drug delivery. With perfect biocompatibility green preparation process, γ-cyclodextrin metal-organic framework (γ-CD-MOF) fabricated cyclodextrin potassium suitable antigen In this study, we modified γ-CD-MOF span-85 fabricate SP-γ-CD-MOF as animal vaccine adjuvants. The ovalbumin (OVA) model was encapsulated...
Objective: To establish an animal model of noise-induced hidden hearing loss (NIHHL), evaluate the dynamic changes in cochlear ribbon synapses and hair cell morphology, observe involvement SIRT1/PGC-1α signaling pathway NIHHL. Methods: Male guinea pigs were randomly divided into three groups: control group, noise exposure resveratrol treatment group. Each group was five subgroups: 1 day, week, 2 weeks, month post groups. The experimental groups received stimulation at 105 dB SPL for h....
BACKGROUND:The aim of this study was to analyze the effects obesity and leptin levels on patients with migraine, observe change in migraineurs. MATERIAL AND METHODS:We enrolled 52 migraine from Headache Clinic Shandong Provincial Hospital into a randomized controlled trial another age-, sex-, BMI-matched healthy subjects as controls. Leptin all were determined by radioimmunoassay. RESULTS:Compared control group, migraineurs revealed no significant (P>0.05). Multivariate Logistic regression...
Acute lung injury (ALI) is characterized by an acute inflammatory process, and oxidative stress in the tissue leads to a lack of effective therapeutics. This study aimed identify whether overexpression transcription factor EB (TFEB) regulates mitophagy protect against lipopolysaccharide (LPS)-induced ALI.We detected expression factors, cytochrome c (Cyt.c) nicotinamide adenine dinucleotide phosphate (NADPH), autophagy-related proteins observed changes histopathology induced ALI rats cell...
Medication overuse headache (MOH) is the third most prevalent type after migraine and tension-type headache. A large number of studies on long-term prognosis have shown that MOH has a high relapse rate treatment. Although relapse-related risk factors been reported, no related research performed in China. Therefore, purpose this study was to analyze evaluate for Eighty-six out-patients Shandong Provincial Hospital who were initially diagnosed with MOH, had successful withdrawal treatment...