Sweta Chekuri
A5028060173- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Hepatitis C virus research
- Pneumothorax, Barotrauma, Emphysema
- Airway Management and Intubation Techniques
- Liver Disease Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Intensive Care Unit Cognitive Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Diverticular Disease and Complications
- Clinical Nutrition and Gastroenterology
- Sepsis Diagnosis and Treatment
- Biliary and Gastrointestinal Fistulas
- Diabetes and associated disorders
- Hepatitis B Virus Studies
- Diagnosis and treatment of tuberculosis
- Blood groups and transfusion
- Autoimmune and Inflammatory Disorders
- Frailty in Older Adults
- Eosinophilic Esophagitis
National Heart Lung and Blood Institute
2023
Montefiore Medical Center
2020-2021
University Health Network
2021
St. Michael's Hospital
2021
Health Sciences Centre
2021
Sunnybrook Health Science Centre
2021
St. Boniface Hospital
2021
Royal Victoria Regional Health Centre
2021
St Michael’s Hospital
2021
University of Manitoba
2021
Thrombosis and inflammation may contribute to morbidity mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill Covid-19.
Thrombosis and inflammation may contribute to the risk of death complications among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation improve outcomes in noncritically ill who are hospitalized Covid-19.In this open-label, adaptive, multiplatform, controlled trial, we randomly assigned were Covid-19 not critically (which was defined as an absence critical care-level organ support at enrollment) receive pragmatically regimens either...
Importance Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity treatment effect (HTE) across individuals. Better understanding HTE could facilitate individualized decision-making. Objective To evaluate for and compare approaches assessing HTE. Design, Setting, Participants Exploratory analysis a multiplatform adaptive RCT vs usual care pharmacologic thromboprophylaxis 3320 enrolled...
Importance Individuals who survived COVID-19 often report persistent symptoms, disabilities, and financial consequences. However, national longitudinal estimates of symptom burden remain limited. Objective To measure the incidence changes over time in disability, status after COVID-19–related hospitalization. Design, Setting, Participants A US multicenter prospective cohort study with 1-, 3-, 6-month postdischarge visits was conducted at 44 sites participating National Heart, Lung, Blood...
Background and Aim To investigate the impact of a sustained virological response (SVR) to hepatitis C virus (HCV) treatment on liver stiffness (LS). Methods LS, measured by transient elastography (FibroScan), demographic laboratory data patients treated with interferon (IFN)-containing or IFN-free regimens who had an SVR24 (undetectable HCV viral load 24 weeks after end treatment) were analyzed using two-tailed paired t-tests, Mann-Whitney Wilcoxon Signed-rank tests linear regression. Two...
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome 2 (SARS-CoV-2) claimed over 4 million lives July 2021 and continues to pose a serious public health threat.Our retrospective study utilized pathogen panel (RPP) results in patients with SARS-CoV-2 determine if coinfection (i.e. positivity an additional virus) was associated more presentation outcomes.All negative influenza/respiratory syncytial virus testing who underwent RPP within 7 days of...
Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has a variable clinical course with significant mortality. Early reports suggested higher rates of SARS‐CoV‐2 infection in patients type A blood and enrichment individuals among COVID‐19 mortalities. Study Design Methods The study includes all hospitalized or an emergency department (ED) visit who were tested for between March 10, 2020 June 8, had positive test result by nucleic acid (NAT) performed on...
Novel coronavirus disease 2019 (COVID-19) is increasingly recognized as a prothrombotic state with high incidence of thrombotic complications, particularly in patients severe clinical course [1,2]. However, 70–81% COVID-19 cases are associated non-severe and recover supportive care [3,4]. The few studies that exist estimate the venous thromboembolism (VTE) risk among general medical wards to be between 5 10%, which strikingly lower than 30% seen ICU [1,5–7].
To determine the association between prone positioning in nonintubated patients with coronavirus disease 2019 and frequency of invasive mechanical ventilation or inhospital mortality.
To assess the real-world effectiveness and cost of simeprevir (SMV), and/or sofosbuvir (SOF)-based therapy for chronic hepatitis C virus (HCV) infection.
Purpose: Esophagitis dissecans superficialis (EDS) is a benign, rare lesion characterized by esophageal mucosal epithelium sloughing. It has no clear etiologic cause, although it been associated with pemphigus vulgaris, ingestion of bisphosphonates, rigid endoscopy, celiac disease and accidental fish bone. We present patient classic findings EDS, in whom HIV may play role. Case Report: A 58-year-old white male controlled medication suffered fall at home. He had head injury without loss...
Introduction: Early enteral nutrition (EEN) is a therapeutic strategy that used in critical illness to reduce morbidity and mortality. There no data on the role of therapy for intubated critically ill COVID-19 patients. The aim our study was assess if early reduced mortality during first wave pandemic. Methods: A retrospective chart review patients >18 years who were mechanically ventilated >48 hours at Montefiore Medical Center from March 2020 November (n = 669) performed. Using landmark...
Introduction: Acute diverticulitis occurs when fecal matter obstructs the orifice of a diverticulum and local infection ensues. Inflammation can result in reduced tissue perfusion leading to focal necrosis perforation. A small perforation may be walled off by omentum present as localized abscess. Disruption vascular integrity siphoning gas into system. Rarely intravascular leads thrombosis septic emboli. Case Report: We are reporting an interesting case 54-year-old male with history alcohol...
Rationale: Prone positioning is a well-established recruitment maneuver to improve oxygenation and decrease mortality in intubated patients with severe acute respiratory distress syndrome (ARDS). There evolving literature utilizing proning among non-intubated hypoxemic novel coronavirus 2019 (COVID-19). However, there paucity of evidence proving sustained improvement patient-centered outcomes. We aimed determine the association between prone COVID-19 incidence invasive mechanical ventilation...
Abstract Introduction: Coronavirus Disease 2019 (COVID-19) deaths have surpassed one million worldwide with limited treatment modalities, and physicians are relying on alternative methods, such as Vitamin D supplementation, to prevent or halt disease progression without direct evidence. Research has proven that vitamin supplementation can inflammation based its role in innate immune response; however, there been studies regarding COVID-19. We aimed determine whether insufficient patients was...