Miguel Ángel Jiménez‐Clavero

ORCID: 0000-0003-2125-9743
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Mosquito-borne diseases and control
  • Malaria Research and Control
  • Animal Disease Management and Epidemiology
  • Viral Infections and Immunology Research
  • Vector-borne infectious diseases
  • Vector-Borne Animal Diseases
  • Viral gastroenteritis research and epidemiology
  • Viral Infections and Outbreaks Research
  • Animal Virus Infections Studies
  • Virology and Viral Diseases
  • Zoonotic diseases and public health
  • Virus-based gene therapy research
  • Viral Infectious Diseases and Gene Expression in Insects
  • SARS-CoV-2 and COVID-19 Research
  • Plant Virus Research Studies
  • Influenza Virus Research Studies
  • SARS-CoV-2 detection and testing
  • Erythrocyte Function and Pathophysiology
  • Blood Coagulation and Thrombosis Mechanisms
  • Bacteriophages and microbial interactions
  • Complement system in diseases
  • Microbial infections and disease research
  • Venomous Animal Envenomation and Studies
  • Molecular Biology Techniques and Applications

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016-2025

Centro de Investigación en Sanidad Animal
2015-2025

Consejo Superior de Investigaciones Científicas
2023-2025

Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria
2014-2023

Centro Regional de Selección y Reproducción Animal
2011-2023

Instituto de Salud Carlos III
2021-2023

Centro de Investigación Biomédica en Red
2023

Fondazione Edmund Mach
2022

Escuela Nacional de Sanidad
2021

Complejo Hospitalario de Salamanca
2021

Usutu virus (USUV) is an African mosquito-borne flavivirus, member of the Japanese encephalitis antigenic group. This avian transmitted by arthropod vectors (mainly mosquitoes Culex pipiens complex). It well known that free-living birds, including migratory species, have potential to disperse certain pathogenic microorganisms. has recently been introduced Europe and spreading through Austria, Hungary, Italy, Spain Switzerland, causing disease in birds humans. Like West Nile virus, USUV may...

10.2807/ese.16.31.19935-en article EN cc-by Eurosurveillance 2011-08-04

Reports of West Nile virus (WNV) associated disease in humans were scarce Spain until summer 2020, when 77 cases reported, eight fatal. Most occurred next to the Guadalquivir River Sevillian villages Puebla del Río and Coria Río. Detection WNV was preceded by a large increase abundance Culex perexiguus neighbourhood where most human occurred. The first infected mosquitoes captured approximately one month before detection cases. Overall, 33 positive pools Cx. pool pipiens found. Serology wild...

10.1080/22221751.2022.2134055 article EN cc-by Emerging Microbes & Infections 2022-10-10

West Nile virus (WNV) is a re-emerging zoonotic pathogen with increasing incidence in Europe, producing recent outbreak 2020 Spain 77 human cases and eight fatalities. However, the factors explaining observed changes of WNV Europe are not completely understood. Longitudinal monitoring wild animals across useful approach to understand eco-epidemiology risk spillover into humans. such studies very scarce up now. Here, we analysed occurrence Usutu (USUV) antibodies 2102 samples collected...

10.1016/j.onehlt.2023.100578 article EN cc-by-nc-nd One Health 2023-06-12

West Nile virus (WNV) is the most widely distributed mosquito-borne flavivirus in world. This can infect humans causing some cases a fatal neurological disease and birds are main reservoir hosts. WNV endemic Spain, human have been reported since 2004. Although different studies analyse how climatic conditions affect dynamics of infection, very few use long-term datasets. Between 2003 2020 total 2,724 serum samples from 1,707 common coots (

10.1080/22221751.2024.2348510 article EN cc-by Emerging Microbes & Infections 2024-04-30

West Nile Virus (WNV) is a zoonotic arbovirus worldwide spread. Seasonal WNV outbreaks occur in the Mediterranean basin since late 1990's with ever-increasing incidence. In Southern Spain endemic, as disease foci - caused by lineage 1 (WNV-L1) strains every year. On contrary, WNV-L2 dominant Europe, so most European sequences available belong to this lineage, WNV-L1 being still scarce.

10.1080/23744235.2024.2348633 article EN cc-by Infectious Diseases 2024-06-05

ABSTRACT Animal enteroviruses shed in the feces of infected animals are likely environmental contaminants and thus can be used as indicators animal fecal pollution. Previous work has demonstrated that bovine enterovirus (BEV) present contaminates waters adjacent to cattle herds BEV-like sequences also shellfish deer from same geographical area. However, little information is available about prevalence, molecular epidemiology, genomic sequence variation BEV field isolates. Here we describe an...

10.1128/aem.71.7.3536-3543.2005 article EN Applied and Environmental Microbiology 2005-07-01

West Nile virus (WNV) is a bird flavivirus capable of infecting horses and humans that transmitted by blood-sucking vectors. In Europe Africa, sporadic infections outbreaks causing human illness deaths have occurred led to 2 mutually nonexclusive hypotheses regarding the circulation WNV in Europe: (1) occurrence endemic sylvatic cycles occasionally result or equine infection, (2) seeding migratory birds from areas where Africa elsewhere cause local epizootic foci eventually lead infection...

10.1089/vbz.2007.0200 article EN Vector-Borne and Zoonotic Diseases 2008-04-09

Abstract A serosurvey for neutralizing antibodies against West Nile virus (WNV) in common coots (Fulica atra) was conducted Doñana, Spain. Antibody prevalence highest 2003, intermediate 2004, and lowest 2005. Some birds seroreverted <1 year after first capture. Seroconversion of suggests local circulation the virus.

10.3201/eid1312.070343 article EN cc-by Emerging infectious diseases 2007-12-01

West Nile virus (WNV) is an emerging zoonotic pathogen whose geographic spread and incidence in humans, horses birds has increased significantly recent years. WNV long been considered a mild causing self-limiting outbreaks. This notion changed as large epidemics with high impact on human animal health. particularly noteworthy since its introduction into North America 1999. There, native bird species have shown to be highly susceptible infection disease mortalities. For this reason, the...

10.1186/1297-9716-42-11 article EN cc-by Veterinary Research 2011-01-18

In recent years, West Nile virus (WNV) has re-emerged in the Western Mediterranean region. As a result, number of complete WNV genome sequences available from this region increased, allowing more detailed phylogenetic analyses, which may help to understand evolutionary history circulating Mediterranean. To aim, present work describes six new outbreaks and surveillance Italy 2008-2009 Spain 2008 2010. Comparison with other different clusters within lineage 1 (clade 1a) confirmed that all...

10.1099/vir.0.033829-0 article EN Journal of General Virology 2011-07-21

The family Flaviviridae, genus Flavivirus, holds many of the world's most prevalent arboviral diseases that are also considered important travel related infections. In cases, flavivirus diagnosis in travelers is primarily based on serology as viremia often low and typically has already been reduced to undetectable levels when symptoms set patients seek medical attention. Serological differentiation between flaviviruses false-positive results caused by vaccination cross-reactivity among...

10.1371/journal.pntd.0003580 article EN public-domain PLoS neglected tropical diseases 2015-03-13

West Nile virus (WNV) is a zoonotic arboviral pathogen transmitted by mosquitoes in cycle involving wild birds as reservoir hosts. The has recently emerged North America and re-emerged Europe. American WNV outbreaks are often accompanied high mortality birds, feature that uncommon reason for this difference unknown, but the intrinsic virulence of viruses circulating each continent and/or susceptibility to disease Palearctic opposed Nearctic bird species could play role. To assess question,...

10.1186/1297-9716-45-33 article EN cc-by Veterinary Research 2014-03-19

Mosquito community composition plays a central role in the transmission of zoonotic vector-borne pathogens. We evaluated how mosquito affects seroprevalence West Nile virus (WNV) house sparrows along an urbanisation gradient area with endemic circulation this virus. sampled 2544 birds and 340829 mosquitoes 45 localities, analysed 15 groups, each containing one urban, rural natural area. WNV was using epitope-blocking ELISA kit micro virus-neutralization test (VNT). The presence antibodies...

10.1038/s41598-018-20825-z article EN cc-by Scientific Reports 2018-02-02

This study aims at assessing the serological cross-reactions existing between three mosquito-borne flaviviruses with avian reservoirs co-circulating in Europe: West Nile (WNV), Usutu (USUV) and Bagaza (BAGV). The is useful for a better interpretation of results diagnostics surveillance. Serum samples obtained from natural host, red-legged partridge (Alectoris rufa), experimentally infected WNV, USUV or BAGV were analysed using two commercially available WNV competition ELISAs suitable...

10.1111/tbed.13262 article EN Transboundary and Emerging Diseases 2019-05-31

Flaviviruses have become increasingly important pathogens in Europe over the past few decades. A better understanding of spatiotemporal distribution flaviviruses France is needed to define risk areas and gain knowledge dynamics virus transmission cycles. Serum samples from 1014 wild boar 758 roe deer 16 departments (administrative units) collected 2009 2014 were screened for flavivirus antibodies using a competitive ELISA (cELISA) technique. found be positive or doubtful by cELISA then...

10.3390/v12010010 article EN cc-by Viruses 2019-12-19
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