A5100663255- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Lymphoma Diagnosis and Treatment
- Silk-based biomaterials and applications
- Contact Dermatitis and Allergies
- Pain Mechanisms and Treatments
- Service-Oriented Architecture and Web Services
- Viral gastroenteritis research and epidemiology
- Viral-associated cancers and disorders
- Respiratory viral infections research
- Advanced Software Engineering Methodologies
- Thyroid Disorders and Treatments
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Gut microbiota and health
- Gastrointestinal motility and disorders
- Animal Virus Infections Studies
- Liver Disease Diagnosis and Treatment
- Nanocluster Synthesis and Applications
- 3D Printing in Biomedical Research
- Virus-based gene therapy research
- Parvovirus B19 Infection Studies
- Electrospun Nanofibers in Biomedical Applications
Universidad de Granada
1996-2025
Central University Hospital of Asturias
2025
Instituto de Investigación Biosanitaria de Granada
1997-2025
Instituto de Investigación Biomédica de Málaga
2015-2024
Clinica Universidad de Navarra
2024
Junta de Castilla y León
2024
Hospital de Sant Pau
2023
Instituto Nacional de Perinatología
2023
Hospital Regional Universitario de Málaga
2007-2022
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2015-2022
3D printing is an additive manufacturing (AM) technique that has quickly disrupted traditional design and strategies. New structures can be manufactured could not fabricated using other methods. These new capabilities are considered by many to hallmark a historic shift representative of industrial revolution. Exciting utilities this evolving technology the fields biomedical engineering translational medicine, particularly in applying three-dimensional (3D) toward enabling on-demand...
Abstract Silk/polyethylene glycol (PEG) hydrogels are studied as self‐standing bioinks for 3D printing tissue engineering. The two components of the bioink, silk fibroin protein (silk) and PEG, both Food Drug Administration approved materials in drug medical device products. Mixing PEG with induces β‐sheet structure formation thus gelation water insolubility due to physical crosslinking. A variety constructs high resolution, shape fidelity, homogeneous gel matrices printed. When human bone...
Gold atomic clusters of only two and three atoms were prepared by a simple electrochemical technique based on the anodic dissolution gold electrode in presence PVP, subsequent electroreduction Au-PVP complexes. These show stable photoluminescent magnetic properties, which make them smallest most elemental (0) building blocks nature (after atoms) bringing new possibilities to construct novel nano/microstructures with large potential interest biomedicine, catalysis, so forth.
Different superparamagnetic iron oxide nanoparticles have been tested for their potential use in cancer treatment, as they enter into cells with high effectiveness, do not induce cytotoxicity, and are retained relatively long periods of time inside the cells. We analyzed interaction, internalization biocompatibility dimercaptosuccinic acid-coated an average diameter 15 nm negative surface charge MCF-7 breast Cells were incubated different intervals, ranging from 0.5 to 72 h. These showed...
Summary Background The peach non‐specific lipid transfer protein, Pru p 3, is the primary sensitizer in fruits and responsible for severe reactions Mediterranean area. Peach allergy frequently associated with other allergies such as peanut. Therefore , it important to assess how specific immunotherapy 3 could affect both peanut tolerance. Objectives To evaluate desensitization immunological changes after 1 year of sublingual ( SLIT ) patients systemic allergic and/or Methods Forty‐eight...
Controlling self-organization and morphology of chemical architectures is an essential challenge in the search for higher energy-conversion efficiencies a variety optoelectronic devices. Here, we report highly ordered donor/acceptor functional material, which has been obtained using principle ionic self-assembly. Initially, electron donor π-extended tetrathiafulvalene electron-acceptor perylene-bisimide were self-organized separately obtaining n- p-nanofibers at same scale. These...
Abstract Background Over 30% of local allergic rhinitis (LAR) patients self‐report bronchial symptoms suggestive asthma, but the relationship between allergen exposure and has not been studied. Objective To investigate whether a counterpart LAR exists. Methods Patients were classified by clinical history, skin prick test/serum specific IgE (sIgE), nasal provocation test (NAPT) into LAR, (AR), nonallergic (NAR) phenotypes. Twenty‐eight 18 AR, 19 NAR self‐reporting asthma 8 healthy controls...
Liver fibrosis is a complex process characterized by the excessive accumulation of extracellular matrix (ECM) and an alteration in liver architecture, as result most types chronic diseases such cirrhosis, hepatocellular carcinoma (HCC) failure. Maresin-1 (MaR1) derivative ω-3 docosahexaenoic acid (DHA), which has been shown to have pro-resolutive anti-inflammatory effects. We tested hypothesis that application MaR1 could prevent development animal model hepatic damage. Sprague-Dawley rats...
Island clusters: By using kinetic control, stable Agn clusters (n≤10) are synthesized in microemulsions. Nanoislands composed of the subnanosized can be deposited onto a substrate (see picture). The characterized by variety methods, including scanning tunneling microscopy (STM), mass spectrometry, UV/Vis spectroscopy, and differential pulse voltammetry.
Scope Sublingual immunotherapy using peach extract enriched in Pru p 3 (Pru 3‐enriched‐SLIT) brings a new perspective to treating patients with allergy lipid transfer proteins. We evaluate the immunological changes induced by 3‐enriched‐SLIT during one year. Methods and results Three groups are included: allergic who receive 3‐enriched‐SLIT, untreated patients, controls. Peripheral blood mononuclear cells obtained before treatment at different time‐points. Monocyte‐derived dendritic (moDCs)...
Maresin-1 (MaR1) is a specialized pro-resolving mediator, derived from omega-3 fatty acids, whose functions are to decrease the pro-inflammatory and oxidative mediators, also stimulate cell division. We investigated hepatoprotective actions of MaR1 in rat model liver ischemia-reperfusion (IR) injury. (4 ng/gr body weight) was administered prior ischemia (1 h) reperfusion (3 h), controls received isovolumetric vehicle solution. To analyze function, transaminases levels tissue architecture...
The formation of Ag nanoparticles by electrochemical techniques has been investigated through a time-resolved UV−vis spectroscopy study. Ag42+ clusters is suggested as the main precursors to particle formation. mechanism also considers electrodeposition which occurs parallel process in Experiments at different current densities show that more important low densities. From fittings change plasmon (λ ≈ 430 nm) and cluster = 250 bands proposed mechanism, kinetic constants disappearance are...
To evaluate the in vivo and vitro responses to nOle e 1 allergic rhinitis (AR) local (LAR) patients sensitized olive tree pollen (OL) confirmed by nasal allergen provocation test (NAPT).Twelve subjects with AR, 12 LAR as control group (CG) were selected. Skin testing NAPT performed. Eosinophilic cationic protein (ECP) tryptase measured lavages before after NAPT. Serum IgE OL allergens was ELISA. Basophil activation tests (BAT) dendritic cell maturation/proliferation studies carried out.All...