A5051257240- Nonlinear Differential Equations Analysis
- Differential Equations and Numerical Methods
- Synthesis and Biological Evaluation
- Parasites and Host Interactions
- Soil and Unsaturated Flow
- Stochastic processes and financial applications
- Mathematical and Theoretical Epidemiology and Ecology Models
- Liver physiology and pathology
- Multicomponent Synthesis of Heterocycles
- MicroRNA in disease regulation
- Differential Equations and Boundary Problems
- Immune Response and Inflammation
- Grouting, Rheology, and Soil Mechanics
- Stability and Controllability of Differential Equations
- Advanced Mathematical Modeling in Engineering
- Synthesis and biological activity
- Circular RNAs in diseases
- Groundwater flow and contamination studies
- Pharmacological Effects of Natural Compounds
- Animal Disease Management and Epidemiology
- Inorganic and Organometallic Chemistry
- Mathematical Biology Tumor Growth
- Drug-Induced Hepatotoxicity and Protection
- Synthetic Organic Chemistry Methods
- Synthesis and Reactions of Organic Compounds
University of Macau
2025
Yunnan University
2025
Qilu Hospital of Shandong University
2024
Xuzhou Medical College
2024
Shihezi University
2019-2024
China Agricultural University
2024
Northeast Normal University
2005-2023
Southern Medical University
2008-2023
Tiangong University
2023
Capital Medical University
2022
Depressive disorder is a common mental characterized by depressed mood and loss of interest or pleasure. As the Herbal medicines are mainly used as complementary alternative therapy for depression. This study aimed at exploring antidepressant activity Huang-lian Jie-du Decoction (HLJDD), evaluating active components potential depression-associated targets. HLJDD was administered on chronic unpredictable mild stress-induced (CUMS) depressive mice. Behavior evaluation performed through force...
Abstract magnified image A series of pyrimido[4,5‐ b ]quinoline and indeno[2′,1′:5,6]pyrido[2,3‐ d ]pyrimidine derivatives were synthesized via the three‐component reaction an aldehyde, 6‐aminopyrimidine‐2,4‐dione 5,5‐dimethyl‐1,3‐cyclohexanedione or 1,3‐indanedione in ionic liquid 1‐ n ‐butyl‐3‐methylimidazolium bromide ([bmim]Br). This protocol has advantages easier work‐up, milder conditions, high yields environmentally benign procedure compared with other methods.
Abstract magnified image In this paper the preparation of 3,3,6,6‐tetramethyl‐9,10‐diaryl‐1,2,3,4,5,6,7,8,9,10‐decahydroacridine‐1,8‐dione derivatives from aldehydes, aromatic amines and 5,5‐dimethyl‐1,3‐cyclohexanedione in 1‐n‐butyl‐3‐methylimidazolium bromide ([bmim]Br) is described. The structures these compounds were characterized by elemental analysis, IR 1 H NMR spectra further confirmed single crystal X‐ray diffraction analysis.
Previous studies have indicated that monocyte chemoattractant protein-1 (MCP‑1), also referred to as C‑C motif chemokine ligand 2, has a significant role in the pathogenesis of sepsis, however, how microRNAs (miRs) contribute this process remains be fully elucidated. In present study, using mouse model disseminated candidiasis, renoprotective effect itraconazole (ITR) and adenovirus‑delivered miR‑124 was investigated. The mice were treated with ITR (50 mg/kg) or transfected mimics via...
Abstract In geological sites containing chemical pollutants, the clay buffer layer (CBL) is frequently utilized to isolate pollutants from external environment. Moreover, hydraulics, mechanics, and chemistry jointly pose impacts on consolidation of CBL diffusion substances. order consider coupled effect (termed chemo‐hydro‐mechanical‐CHM), a one‐dimensional model that fully considers CHM coupling (such as convection, ultrafiltration, osmotic efficiency) established. developed model, excess...
Abstract Background Bovine viral diarrhea (BVD) is an acute febrile infectious disease caused by the bovine virus (BVDV), which has brought huge economic losses to world's cattle industry. At present, commercial inactivated BVDV vaccines may cause some adverse reactions during use. This study aims develop a safer and more efficient vaccine. Methods Here, we described generation preclinical efficacy of hydrogen peroxide (H 2 O ) type 1 vaccine in mice, administered it separately with...
The labor shortage and rising costs in the greenhouse industry have driven development of automation, with core autonomous operations being positioning navigation technology. However, precise complex environments narrow aisles poses challenges to localization technologies. This study proposes a multi-sensor fusion robot based on ultra-wideband (UWB), an inertial measurement unit (IMU), odometry (ODOM), laser rangefinder (RF). system introduces confidence optimization algorithm weakening...
The interactions between chemical, hydraulic, and mechanical processes in clay soils has garnered significant attention various fields. It is important to study the transport of chemical substances deformation layer under combined action solution loading. Clay a typical porous medium, primarily composed soil skeleton pores, with shape, size, distribution pores being random, making it difficult accurately describe using traditional geometry. A fractal model can be used simulate soils. This...
Abstract magnified image Various biologically important quinoxaline derivatives were efficiently synthesized in excellent yields by the reaction of 1,2‐diketones and 2‐nitroaniline, benzofuroxan or 1,2‐dinitrobenzene promoted SnCl 2 2H O. The role stannous chloride is acting as both reductive agent catalyst this synthesis. This new method has advantages accessible starting materials, convenient manipulation, short time high yields.
CircRNA is a type of closed circular non-coding RNA formed by reverse splicing and plays an important role in regulating the growth development plants animals. To investigate function circ-FoxO3 mouse myoblast cells’ (C2C12) differentiation proliferation, we used RT-qPCR to detect expression level cells at different densities stages, specific interference fragment was inhibit observe its effect on proliferation differentiation. We found that increased with prolongation time, decreased cells....
SUMMARY Treatment of liver fibrosis associated with Schistosoma japonicum ova-induced granulomas remains a challenging proposition. Paeoniflorin (PAE, C 23 H 28 O 11 ) has anti-inflammatory, anti-allergic, and immunoregulatory effects it is commonly used in Chinese Herbal prescriptions to treat hepatic disorders. The present study was carried out investigate the PAE on mice infected S. explore its possible mechanism. Upon pathological examination PAE-treated mice, size egg granuloma, scores,...
Bovine Viral Diarrhea Virus (BVDV) is the main pathogen of bovine viral diarrhea disease (BVD), which leads to enormous economic losses in cattle industry. A sensitive and specific detection for BVDV advantageous control BVDV. Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have been used detecting virus RNA. In this study, expression purification LwCas13a protein was optimized RNase activity vitro verified. CRISPR-LwCas13a system could detect RNA with high...
Treatment of liver fibrosis associated with Schistosoma japonicum ova-induced granulomas remains a challenging proposition. There is close relationship between high levels interleukin-13 (IL-13) and the development severe schistosome fibrosis. In contrast, IL-13 receptor (R) α2 has an effective role in attenuation profibrosis. Several Chinese herbs have significant beneficial effects disease. Accordingly, purpose present study was to investigate therapeutic effect Paeoniflorin (PAE) on A...
Myofascial trigger points (MTrPs) are the primary etiological characteristics of chronic myofascial pain syndrome. Receptor tyrosine kinases (RTKs) associated with signal transduction in central mechanisms pain, but role RTKs peripheral MTrPs remains unclear. The current study aimed to identify expression and elucidate molecular through which platelet-derived growth factor receptor-α (PDGFR-α) induces contraction knots inflammatory pain-like behavior a rat model points.
In this article we introduce a number of explicit schemes, which are amenable to Khasminski's technique and particularly suitable for highly nonlinear stochastic differential equations (SDEs). We show that without additional restrictions those guarantee the exact solutions possess their boundedness in expectation with respect certain Lyapunov-type functions, numerical converge strongly finite-time. Moreover, based on convergence theorem nonnegative semimartingales, positive results about...
This paper studies the numerical methods to approximate solutions for a sort of McKean-Vlasov neutral stochastic differential delay equations (MV-NSDDEs) that growth drift coefficients is super-linear. First, we obtain solution MV-NSDDE exists and unique. Then, use particle method, which on basis results about propagation chaos system, deal with approximation law. Furthermore, construct tamed Euler-Maruyama scheme respect corresponding system rate convergence. Combining convergence get error...