A5101784893- Hydraulic and Pneumatic Systems
- Animal Virus Infections Studies
- Advanced Sensor and Control Systems
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Parasites and Host Interactions
- Flow Measurement and Analysis
- Fuel Cells and Related Materials
- Industrial Technology and Control Systems
- SARS-CoV-2 and COVID-19 Research
- Advanced Algorithms and Applications
- HIV Research and Treatment
- Salmonella and Campylobacter epidemiology
- Aquaculture Nutrition and Growth
- Oil and Gas Production Techniques
- Bacteriophages and microbial interactions
- Control Systems in Engineering
- Probiotics and Fermented Foods
- Water Systems and Optimization
- Macrophage Migration Inhibitory Factor
- Liver physiology and pathology
- Sensorless Control of Electric Motors
- Granular flow and fluidized beds
- Cutaneous Melanoma Detection and Management
- Toxoplasma gondii Research Studies
Zhejiang Ocean University
2024
Jiangsu Academy of Agricultural Sciences
2021-2024
Yangzhou University
2021-2024
Huazhong University of Science and Technology
2022-2023
China Three Gorges Corporation (China)
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2010-2023
Tiandi Science & Technology (China)
2023
Coal Industry Taiyuan Design and Research Institute (China)
2023
Zoomlion (China)
2023
Jiangsu Institute of Parasitic Diseases
2023
ABSTRACT Terminal differentiation of B cells and hypergammaglobulinemia are hallmarks B-cell hyperactivity in HIV disease. Plasmablasts terminally differentiating that circulate transiently the blood following infection or vaccination; however, infection, they arise early maintained at abnormally high levels viremic individuals. Here we show only a small fraction plasmablasts individuals is specific. Assessment plasmablast immunoglobulin isotype distribution revealed increased IgG + most...
Coronaviruses (CoVs) are important pathogens for humans and other vertebrates, causing severe respiratory intestinal infections that have become a threat to public health because of the potential interspecies transmission between animals humans. Therefore, development safe, effective vaccines remains top priority control CoV infection. The unique immunological characteristics featuring messenger RNA (mRNA) present an advantageous tool coronavirus vaccine development. Here, we designed two...
Porcine deltacoronavirus (PDCoV) can cause diarrhea and dehydration in newborn piglets. Here, we developed a double antibody sandwich quantitative enzyme-linked immunosorbent assay (DAS-ELISA) for detection of PDCoV by using specific monoclonal against the N protein an anti-PDCoV rabbit polyclonal antibody. Using DAS-ELISA, limit recombinant virus titer were approximately 0.5 ng/mL 103.0 TCID50/mL, respectively. A total 59 intestinal 205 fecal samples screened presence DAS-ELISA reverse...
As one of the most important causative agents severe gastroenteritis in children, piglets, and other young animals, species A rotaviruses have adversely impacted both human health global swine industry. Vaccines against (RVs) are insufficiently effective, no specific treatment is available. To understand relationships between porcine RV (PoRV) infection enterocytes terms cellular lipid metabolism, we performed an untargeted liquid chromatography mass spectrometry (LC-MS) lipidomics analysis...
Therapeutic antibody development is one of the fastest growing areas pharmaceutical industry. Generating high-quality monoclonal antibodies against a given therapeutic target very crucial for success drug development. However, due to immune tolerance, some proteins that are highly conserved between mice and humans not immunogenic in mice, making it difficult generate using conventional approach.In this report, impaired tolerance NZB/W was exploited or self-antigens. Using two human antigens...
One mcr-1-carrying ST34-type Salmonella Typhimurium WW012 was cultured from 3,200 ready-to-eat (RTE) pork samples in 2014 China. Broth dilution method applied to obtain the antimicrobial susceptibility of WW012. matting assays were carried out detect transferability this phenotype and whole-genome sequencing performed analyze its genomic characteristic. Thirty 3200TE positive for three most frequent serotypes identified as S. Der by (n = 8), 6), Enteritidis 6). isolate (S. WW012) RTE...
Calf diarrhea is one of the common diseases involved in process calf feeding. In this study, a sample that tested positive for bovine coronavirus and astrovirus was subjected to high-throughput sequencing. The reassembly revealed complete genomes norovirus, astrovirus, kobuvirus, S gene coronavirus. Phylogenetic analysis showed ORF2 region had lowest similarity with other strains gathered Mamastrovirus unclassified genogroup, suggesting new serotype/genotype could appear. Compared most...
A high-temperature gas mixing chamber is a type of mechanical device which has been widely used to obtain airflow at specific high temperature. When temperature environment test for aviation equipment performed, the should exceed 1,000 K and change fast. However, existing devices cannot meet requirements speed uniformity tests. To solve problem low uniformity, this paper proposes an innovative design. The proposed design allows cold hot gases be injected in directions perpendicular each...
The spherical distribution pairs of the plunger and cylinder friction, has an important influence on performance port plate axial piston pump. Based analysis fluid viscosity change with pressure temperature, considering friction differential flow shear flow, establishes mathematics model pair leakage. simulation using MATLAB software, leakage rate is not proportional to pressure, but increase was increased, coefficient temperature viscosity, correction increases obviously, so in choice...
Non-human primates (NHP) are the only animal model suitable to evaluate protection efficacy of HIV-1 vaccines. It is important understand how and when neutralizing antibodies (nAbs) with specificities similar those human broadly (bnAbs) develop in NHPs. To address these questions, we determined plasma neutralization two macaques which developed breadth after long-term simian/human immunodeficiency virus (SHIV) infection identified escape mutations by analyzing env sequences from longitudinal...
Abstract Background Human astroviruses (HAstVs) are one of the important causes acute gastroenteritis in children. Currently, eight HAstV genotypes have been identified and all but two (HAstV-6 HAstV-7) fully sequenced. We here sequenced analyzed complete genome a HAstV-6 strain (192-BJ07), which was Beijing, China. Results The 192-BJ07 consists 6745 nucleotides. displays 77.2-78.0% nucleotide sequence identity with other exhibits amino acid identities 86.5-87.4%, 94.2-95.1%, 65.5-74.8%...
Background: The single position control or force of the electro-hydraulic servo system has long been unable to meet actual needs production and life. To achieve a good effect solve various problems in real life, people no longer only consider control. Objective: proposed method provides technical support for multi-objective collaborative system, completes requirements multitasking operation, improves positioning accuracy response velocity realizes synergy between force. Methods: A outer loop...