- Essential Oils and Antimicrobial Activity
- Proteins in Food Systems
- Phytochemistry and Biological Activities
- Food composition and properties
- Nanoparticles: synthesis and applications
- Natural Antidiabetic Agents Studies
- Agricultural Practices and Plant Genetics
- Nuts composition and effects
- Medicinal Plants and Neuroprotection
- Phytochemical Studies and Bioactivities
- Biological and pharmacological studies of plants
- Food Chemistry and Fat Analysis
- Cholinesterase and Neurodegenerative Diseases
- Polysaccharides Composition and Applications
- Global Maternal and Child Health
- Plant chemical constituents analysis
- Saffron Plant Research Studies
- Freshwater macroinvertebrate diversity and ecology
- Berberine and alkaloids research
- Ophthalmology and Visual Health Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Edible Oils Quality and Analysis
- Medicinal Plants and Bioactive Compounds
- Healthcare Policy and Management
- Advanced Nanomaterials in Catalysis
Purdue University West Lafayette
2024
University of Balochistan
2023
Hazara University
2023
Fujian University of Traditional Chinese Medicine
2023
Dhulikhel Hospital
2022
Shaheed Benazir Bhutto University
2014-2021
Beaumont Hospital, Royal Oak
2021
Mehran University of Engineering and Technology
2019
Quaid-e-Awam University of Engineering, Science and Technology
2019
Ch. Pervaiz Elahi Institute of Cardiology, Multan
2017
In the present work AuNPs were synthesized by an eco-friendly, fast, one-pot and green synthetic route using Longan fruit juice as a reducing, capping stabilizing agent.
Trillium govanianum rhizome is used as an analgesic and anti-inflammatory remedy in traditional medicine northern Pakistan. In attempt to establish its medicinal value, the present research evaluated potential of T. govanianum. The vivo activity extract fractions was investigated carrageenan induced paw edema assay. vitro suppression oxidative burst extract, isolated compounds assessed through luminol-enhanced chemiluminescence assayed chemical thermal nociceptive pain models. crude methanol...
Background: Gastrodin has been widely used clinically in China as an antihypertensive drug. However, its effect on hypertensive renal injury is yet to be elucidated. The current study aimed investigate the effects of gastrodin and underlying mechanisms by network pharmacology analysis validation vivo vitro . Methods: A total 10 spontaneously rats (SHRs) were randomly categorized into following two groups: SHR + groups. Wistar Kyoto (WKY) control group ( n = 5). was intragastrically...
The present study, conducted at the Malakandair Agriculture Research Farm, University of Peshawar, in 2022, evaluated efficacy six insecticides against Leucinodes orbonalis (brinjal fruit borer) under field conditions. Brinjal was planted with a 30 cm plant-to-plant distance and 60 row-to-row distance. study assessed various insecticides, including FANTASTIC (Chlorantraniliprole 0.4% GR), AAKRAMAK (Novaluron 5.25% + Emamectin Benzoate 0.9% SC), FANTASY (Fipronil 5% JOKER 80% WDG),...
Background: Odonates, including dragonflies and damselflies, play a crucial role in freshwater ecosystems, serving as bioindicators of environmental health natural pest control agents. Their diversity distribution are influenced by habitat availability, climatic conditions, water quality. Despite their ecological importance, limited studies have been conducted on the biodiversity Anisoptera Dir Lower, Khyber Pakhtunkhwa. This study aims to document species richness, evenness, abundance...
Karl Marx's claim that religion serves as the opium of people suggests it is often used a tool to silence oppressed and make them bear their agonies sufferings in name religion. This study critically examines assertion, arguing rather than being an opiate masses, Islam challenges social injustice works catalyst for positive change.Using qualitative research approach, this analyzes historical evidence from Quran, Hadith, Prophet's biography demonstrate how effectively confronted injustice,...
In the current research, attempt is made to fabricate a nanoemulsion (NE) containing an antifungal agent. The prepared formulation has been expected enhance skin penetration. It also studied for in vitro drug release and toxicity assessment. Spontaneous titration method was used preparation of NE. Prepared NE were characterized their charge, size, morphology, rheological behaviour, profile, permeability. permeation irritation investigated. activity inspected using well agar diffusion method....
To evaluate nationwide pediatric critical care facilities and resources in Pakistan.Cross-sectional observational study.Accredited training Pakistan.None.None.A survey was conducted using the Partners Health 4S (space, staff, stuff, systems) framework, via email or telephone correspondence. We used a scoring system which each item our checklist given score of 1, if available. Total scores were added up for component. Additionally, we stratified analyzed data between public private healthcare...
The effects and underlying mechanisms of gastrodin treatment on hypertensive vascular dysfunction proliferation smooth muscle cells (VSMCs) were determined in vitro vivo. Using a pharmacological target network interaction analysis, 151 common targets PPI identified containing the top 10 hub genes. Kyoto encyclopedia genes genomes (KEGG) analysis PI3K/AKT pathway as significantly enriched pathway. Both spontaneous rats (SHRs) Wistar used to assess therapeutic hypertension. Gastrodin SHRs...
A phytochemical investigation on the ethyl acetate soluble fraction of Zanthoxylum armatum led in isolation two new prenylated alkaloids 2,6,7-trimethoxy-8-(3-methyl-2-butenyl)carbazole-3-carbaldehyde (1) and methyl-2,6,7-trimethoxy-8-(3-methyl-2-butenyl)carbazole-3-carboxylate (2), along with three known lignans cisamin (3), methyl pirpirtol (4), fargesin (5) one alkaloid dictamine (6). Their structures were established basis spectroscopic crystallographic analysis by comparison data those...
Nelumbo nucifera seeds' essential oil (EO), crude extract and subsequent fractions were evaluated for their DPPH, ABTS superoxide anion-free radical scavenging cholinesterase inhibitory activities. The ethyl acetate fraction EO showed outstanding antioxidant activities with IC50 values of 191, 450 μg/mL (DPPH), 123, 221 (ABTS) 69, 370 (superoxide anion). also caused significant inhibition acetylcholinesterase butyrylcholinesterase 70 ± 0.6, 64 0.8 75 0.3, 58 0.2, in dose-dependent manner....
Phytochemical investigation on the chloroform soluble fraction of Cirsium arvense resulted in isolation five compounds namely Ciryneol C, Scopoletin, Pectolinarigenin-7-O-glucopyranoside, Acacetin and 6, 7-Dimethoxycoumarin. Their structures have been elucidated by EIMS, HREIMS, 1H 13C NMR spectroscopic methods. These isolated for first time from this plant. All were tested their antibacterial antifungal activities
A phytochemical investigation on the ethyl acetate soluble fraction of Lonicera quinquelocularis (whole plant) led to first time isolation one new phthalate; bis(7-acetoxy-2-ethyl-5-methylheptyl) phthalate (3) and two benzoates; neopentyl-4-ethoxy-3, 5-bis (3-methyl-2-butenyl benzoate (4) neopentyl-4-hydroxy-3, (5) along with known compounds bis (2-ethylhexyl (1) dioctyl (2). Their structures were established basis spectroscopic analysis by comparison available data in literature. All (1–5)...
Abstract. In this study, the physicochemical properties of walnut (Juglans regia L.) oils collected from different sites in Khyber PakhtoonKhwa (KPK), Pakistan were investigated. The obtained showed variation viscosity, surface tension, density, acid, saponification, and iodine values. oil Madyan (Sample E) lowest density (0.981 g/cm3), tension (34.76×10-3 N/m), viscosity (15.0595 cp) saponification values 84.15 (mg KOH/g oil) acid value 3.5 KOH per gram amongst all. all also compared to...
Drug-resistant gonorrhea is caused by the bacterial pathogen Neisseria gonorrhoeae, for which there no recommended oral treatment. We have demonstrated that FDA-approved human carbonic anhydrase inhibitor ethoxzolamide potently inhibits N. gonorrhoeae; however, not effective at reducing gonorrhoeae bioburden in a mouse model. Thus, we sought to optimize pharmacokinetic properties of scaffold. These efforts resulted analogs with improved activity against increased metabolic stability liver...
Maple sap is a sterile liquid extracted from maple trees in early spring. However, it rapidly contaminated during handling and processing. Typically, raw undergoes reverse osmosis process for concentration; meanwhile, this operation also concentrates the microorganisms present sap. The enrichment of affects quality its derived products remarkably. Consumption concentrated as novel natural soft drink has increased considerably recent years, mainly North America but worldwide. Adequate...
Two new benzoates, asiatoate A (1) and B (2), have been isolated from the ethyl acetate soluble fraction of Buddleja asiatica whole plant. Their structures were elucidated with help spectroscopic data. Both showed significant inhibitory effect on acetylcholinesterase (AChE) butylcholinesterase (BChE) in a dose-dependent manner. The IC50 values compounds 1-2 5.54 8.34 μM against AChE while 30.94 35.94 BChE, respectively.