A5033490823- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Circular RNAs in diseases
- Surgical site infection prevention
- RNA Research and Splicing
- Fungal Biology and Applications
- Lung Cancer Treatments and Mutations
- Nosocomial Infections in ICU
- Surgical Sutures and Adhesives
- Computational Drug Discovery Methods
- Ferroptosis and cancer prognosis
- Digital Imaging in Medicine
- HER2/EGFR in Cancer Research
- MicroRNA in disease regulation
- Chemical synthesis and alkaloids
- Alkaloids: synthesis and pharmacology
Cangzhou Central Hospital
2013-2023
Hebei Medical University
2022
People's Hospital of Cangzhou
2021
Hospital of Hebei Province
2017
Abstract This study aims to examine whether miR-448 reverses the cisplatin (DDP) resistance in lung cancer by modulating SATB1. QRT-PCR and immunohistochemistry were used SATB1 expressions DDP-sensitive -resistant patients. A microarray was investigate cytoplasmic/nucleic ratio (C/N ratios) of genes A549 cells targeted miR-448, followed Dual-luciferase reporter gene assay. A549/DDP transfected with mimics/inhibitors or without siRNA MTT assay, Edu staining, flow cytometry, qRT-PCR western...
Background: Gastric cancer (GC) is a malignant tumor of digestive tract with high mortality. Elucidating the molecular mechanisms GC and obtaining new targets are particularly important for prevention treatment GC. The discovery long non-coding RNAs (lncRNAs) provides possibility further elucidating discovering markers. Aim: Here, we aimed to explore function mechanism lncRNA PITPNA-AS1 in Methods: High-throughput microarray was used compare differences expression profiles between tissues...
Gastric cancer (GC) is a prevalent malignancy in the digestive system that poses serious threat to human health. Anti-silencing function 1B (ASF1B) performs an important role progression of numerous tumors; however, its GC still requires further elucidation. Using data from The Cancer Genome Atlas, expression levels ASF1B tissues were analyzed and survival curve for high-ASF1B low-ASF1B groups was plotted using Kaplan-Meier method. Reverse transcription-quantitative PCR performed evaluate...
Objective To investigate the application and effect of bundle nursing intervention combining with ventilator pipeline disinfection in prevention ventilator-associated pneumonia (VAP) . Methods A total 100 cases who had not received ICU ward, Cangzhou Central Hospital between February 2012 to January 2014 were treated as control group, while another same ward from 2016 observation group. Incidence VAP, length mechanical ventilation time stay two groups compared. Results In...