A5001825499- Medical Imaging and Analysis
- Spine and Intervertebral Disc Pathology
- Lower Extremity Biomechanics and Pathologies
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Spinal Fractures and Fixation Techniques
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Orthopedic Surgery and Rehabilitation
University of Leeds
2017-2025
Abstract Finite element studies of the tibiofemoral joint have increased use in research, with attention often placed on material models. Few assess effect meniscus modelling assumptions image-based models contact mechanics outcomes. This work aimed to knee and kinematics. A sensitivity analysis was performed using three specimen-specific one generic model. The representing attachment tibia (shape roots position attachment), properties meniscus, shape alignment were evaluated, creating 40...
Subject-specific finite element models of knee joint contact mechanics are used in assessment interventions and disease states. Cartilage thickness distribution is one factor influencing the pressure. Precision cartilage geometry capture varies between imaging protocols. This work evaluated precision needed for prediction tibiofemoral by comparing model outputs to experimental measurements three cadaveric specimens. Models with location-specific were compared those a uniform thickness, fixed...
Image-based continuum-level finite element models have been used for bones to evaluate fracture risk and the biomechanical effects of diseases therapies, capturing both geometry tissue mechanical properties. Although vertebrae various species developed, an inter-species comparison has not yet investigated. The purpose this study was derive species-specific modelling methods compare accuracy image-based across species. Vertebral specimens were harvested from porcine (N = 12), ovine 13) bovine...
Patient variation affects the outcomes of a range spinal interventions, from disc replacement to vertebral fixation and vertebroplasty. Statistical Shape Appearance Modelling (SSAM) can be used describe anatomical pathological differences within population. To better understand how bone density shape affect load transfer with respect surgical treatments, Finite Element (FE) models generated SSAM. The aim for this study is whether geometric as well multiple levels incorporated into single...
Abstract Vertebroplasty has been widely used for the treatment of osteoporotic compression fractures but efficacy technique questioned by outcomes randomized clinical trials. Finite‐element (FE) models allow an investigation into structural and geometric variation that affect response to augmentation. However, current specimen‐specific FE are limited due their poor reproduction cement augmentation behavior. The aims this study were develop new methods modeling vertebral body in both a...
The successful development of cartilage repair treatments for the knee requires understanding biomechanical environment within joint. Computational finite element models play an important role in non-invasively mechanics, but it is to compare model findings experimental data. purpose this study was develop a methodology generating subject-specific porcine tibiofemoral joints that robust and valid over multiple different constraint scenarios. predictions two knees were compared studies on...
Osteoarthritis (OA) is the most prevalent chronic rheumatic disease worldwide with knee OA having an estimated lifetime risk of approximately 14%. Autologous osteochondral grafting has demonstrated positive outcomes in some patients, however, understanding biomechanical function and how treatments can be optimised remains limited. Increased short-term stability grafts allows cartilage surfaces to remain congruent prior graft integration. In this study methods for generating specimen specific...
Abstract Osteochondral grafting has demonstrated positive outcomes for treating articular cartilage defects by replacing the damaged region with a cylindrical graft consisting of bone layer cartilage. However, factors that cause subsidence are not well understood. The aim this study was to develop finite element (FE) models osteochondral grafts within tibiofemoral joint, suitable an investigation parameters affecting stability. Cadaveric femurs were used experimentally calibrate properties...