- Pancreatic and Hepatic Oncology Research
- Poisoning and overdose treatments
- Neuroscience of respiration and sleep
- Veterinary Pharmacology and Anesthesia
- Forensic Toxicology and Drug Analysis
- Esophageal and GI Pathology
- Vascular Anomalies and Treatments
- Insect and Pesticide Research
- Cancer Genomics and Diagnostics
- GDF15 and Related Biomarkers
- Cancer Cells and Metastasis
- Opioid Use Disorder Treatment
- Autopsy Techniques and Outcomes
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Folate and B Vitamins Research
- Trauma and Emergency Care Studies
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Cancer, Lipids, and Metabolism
- Urinary and Genital Oncology Studies
- Pancreatitis Pathology and Treatment
- Cardiac Arrhythmias and Treatments
Office of Chief Medical Examiner
2017-2024
Hospital Nacional Cayetano Heredia
2020
St Martins Hospital
2020
New York University
2017
Allegheny Health Network
2015
Allegheny General Hospital
2013-2014
University of Buenos Aires
1997
Abstract Xylazine is an emerging adulterant with fentanyl in fatal drug intoxications, which has public health, safety, and criminal investigative implications. a nonnarcotic sedative used for analgesia muscle relaxation exclusively veterinary medicine. Its chemical structure similar to clonidine acts as central α-2 agonist may cause bradycardia transient hypertension followed by hypotension. We report the detection of xylazine 42 deaths Connecticut from March August 2019. combined opioid or...
Xylazine, a clonidine analog, is nonopioid veterinary tranquilizer not intended for human use.Recreational drugs such as cocaine, heroin, and fentanyl are often adulterated with agents xylazine to enhance drug effects or increase street value by increasing net weight (1).Xylazine known cause hypotension bradycardia when used in humans (2).Although controlled substance the United States, cannot be purchased without license.Misuse of was reported Puerto Rico early 2000s (3).Recreational use...
Abstract We report 8 children younger than 2 years who died from acute illicit fentanyl intoxications in Connecticut between 2020 and 2022. The Office of the Chief Medical Examiner (CT OCME) investigates all unexpected, violent, suspicious deaths Connecticut. CT OCME's electronic database was searched for by age. All underwent autopsies toxicology testing. ages ranged 28 days to (mean age, 12 months). causes death involved with 1 having xylazine, para-fluorofentanyl, cocaine morphine....
Abstract As a powerful tool for discovering and documenting injury, the forensic autopsy has been incorporated into trauma care quality improvement. Autopsy findings are used to determine Abbreviated Injury Scale (AIS) Severity Score (ISS) assess patient's severity. Clinical services use reports educate, improve patient care, strengthen information in epidemiological injury prevention studies. However, there is sometimes disconnect between pathologist's descriptions needed by service AIS/ISS...
Folate receptor alpha (FRα) is a membrane protein that transports folate into cells.In invasive breast cancer (IBC), FRα associated with recurrence and mortality.The aim of this study was to evaluate expression by immunohistochemistry (IHC) in four subsets IBC: (P) Non-HER2 amplified cases increased CEP17 copies, (A) HER2 amplified, (T) triple negative phenotype (N) non-HER2 no increase copies correlate these other prognostic predictive factors.A total 70 IBC were tested: 10 N, 20 P, 18 A,...
Introducción. La neoplasia mucinosa papilar intraductal (IPMN) se diagnostica ahora con mayor frecuencia debido al usode los métodos de imágenes, y conlleva un desafío clínico su manejo seguimiento por probable transformación maligna. Objetivos. Conocer las características ecoendoscopía (USE), evolución clínica sobrevida pacientes diagnosticados IPMN USE. Materiales métodos. Estudio cohorte retrospectivo análisis en USE entre 2013 2018 el Hospital Nacional Edgardo Rebagliati Martins (HNERM)....
La formación de una fístula entre arterias gran calibre y el tubo digestivo es complicación infrecuente la cirugía reconstructiva los grandes vasos sanguíneos secundario al uso prótesis vasculares, cuales se manifiestan con hemorragias masivas elevada mortalidad. Presentamos dos casos aorto-entérico carotideo-esofágicoque comparten características comunes como manifestación clínica hemorragia digestiva masiva mortal en pacientes antecedentes colocación vasculares.