A5053520821- Breast Cancer Treatment Studies
- Colorectal Cancer Treatments and Studies
- Trauma and Emergency Care Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Spine and Intervertebral Disc Pathology
- Pancreatic and Hepatic Oncology Research
- Nonmelanoma Skin Cancer Studies
- Trauma Management and Diagnosis
- Acute Myeloid Leukemia Research
- Otolaryngology and Infectious Diseases
- Acute Lymphoblastic Leukemia research
- Cancer Genomics and Diagnostics
- Intestinal Malrotation and Obstruction Disorders
- Medical Malpractice and Liability Issues
- Injury Epidemiology and Prevention
- Hormonal and reproductive studies
- Cancer survivorship and care
- COVID-19 and healthcare impacts
- Streptococcal Infections and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Autopsy Techniques and Outcomes
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Surgical Simulation and Training
- Head and Neck Cancer Studies
Duke University
2024-2025
Duke Medical Center
2025
Yale New Haven Hospital
2022-2024
Duke Cancer Institute
2024
Nationwide Children's Hospital
2024
Yale University
2023
Cardiff University
2021-2023
Good Samaritan Hospital
2019
TriHealth
2017
Abstract Introduction While KRAS mutations represent the primary oncogenic driver in pancreatic ductal adenocarcinoma (PDAC), association between codon-specific alterations and patient outcomes remains poorly elucidated, largely due to a lack of datasets coupling genomic profiling with rich clinical annotations across disease stages. Patients Methods We utilized AACR’s GENIE Biopharma Consortium Pancreas v1.2 dataset test associating clinicogenomic features PDAC patients diagnosed localized...
Importance Current practices in axillary treatment for patients with breast cancer who receive a mastectomy node-positive disease are unknown. For postmastectomy radiotherapy (PMRT), the addition of lymph node dissection (ALND) may result significant overtreatment. Objectives To evaluate trends limited nodal metastases and identify factors that can be targeted to reduce Design, Setting, Participants A retrospective cohort study was conducted identified from National Cancer Database received...
Breast cancer treatment patterns and quality of care among patients experiencing incarceration are underexplored. This study examined associations between breast disease characteristics.
This study aims to quantitatively assess use of the NSQIP surgical risk calculator (NSRC) in contemporary practice and identify barriers potential interventions that might increase use. We performed a cross-sectional surgeons at seven institutions. The primary outcomes were self-reported application general clinical specific scenarios as well reported In our sample 99 (49.7% response rate), 73.7% NSRC past month. Approximately half (51.9%) respondents infrequent (<20% preoperative...
Intestinal malrotation is a congenital anomaly primarily diagnosed in children, with limited cases reported adults. Prompt recognition necessary to prevent life-threatening complications including bowel ischemia and death. We present rare case of adult intestinal highlighting difficulty diagnosis surgical management.A 37-year-old Caucasian woman presented 3-day history worsening diffuse abdominal pain, three months status-post laparoscopic appendectomy. CT scan contrast the abdomen pelvis...
10014 Background: Minimal (measurable) residual disease (MRD) at end of induction (EOI) therapy is a strong predictor outcome in pediatric B-ALL. Currently, EOI MRD assessed bone marrow (BM). We hypothesized that the highly sensitive assay, high-throughput sequencing (HTS) immunoglobulin loci, can effectively monitor peripheral blood (PB) and may provide less invasive way to track response. Methods: conducted HTS on paired BM PB samples from 808 NCI standard risk (SR) B-ALL patients enrolled...
Abstract As a powerful tool for discovering and documenting injury, the forensic autopsy has been incorporated into trauma care quality improvement. Autopsy findings are used to determine Abbreviated Injury Scale (AIS) Severity Score (ISS) assess patient's severity. Clinical services use reports educate, improve patient care, strengthen information in epidemiological injury prevention studies. However, there is sometimes disconnect between pathologist's descriptions needed by service AIS/ISS...
Aims Traumatic central cord syndrome (CCS) typically follows a hyperextension injury and results in motor impairment affecting the upper limbs more than lower, with occasional sensory urinary retention. Current evidence on mortality long-term outcomes is limited. The primary aim of this study was to assess five-year CCS, determine any difference between management groups or age. Methods Patients aged ≥ 18 years traumatic CCS January 2012 December 2017 Wales were identified. Patient...
Introduction: Necrotizing soft tissue infections (NSTI) result in severe destruction. Mainstay of treatment is surgical debridement and antimicrobial therapy. There are no definitive recommendations regarding the duration antibiotics for NSTI. This study aims to evaluate length therapy following optimal source control. Methods: was a retrospective medical chat review five-hospital system. Patients treated an NSTI (January 2015 December 2021) were identified. Adult patients who received...
Case: We report a case of self-inflicted transoral gunshot injury in 24-year-old man resulting mechanical block to cervical rotation. Anterior surgical removal the pellet was successful with patient experiencing no early or long-term functional deficits. Conclusion: Given rarity spine from wound without complications, this unique supports role operative management such injuries.
Abstract Aim Low back pain (LBP) with associated lumbar radiculopathy is common. Clinical assessment utilises the straight leg raise (SLR) test and more specific crossed (XSLR) test. Patient reported outcome measure (PROMs) scores can assess contributary biopsychosocial factors to pain. Evidence shows links between psychosocial issues, but little has assessed them in relation clinical examination. The aim of this study was significance SLR XSLR sign on PROMs patients an MRI-confirmed disc...