A5021026374- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Retinal and Macular Surgery
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Systemic Lupus Erythematosus Research
- Ocular Surface and Contact Lens
- Vasculitis and related conditions
- Retinopathy of Prematurity Studies
- Syphilis Diagnosis and Treatment
- Retinal Imaging and Analysis
- Cytomegalovirus and herpesvirus research
- Ophthalmology and Visual Impairment Studies
- Biomedical Ethics and Regulation
- Traumatic Ocular and Foreign Body Injuries
- Vascular Malformations Diagnosis and Treatment
- Ocular Oncology and Treatments
- Bartonella species infections research
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- CNS Lymphoma Diagnosis and Treatment
- Herpesvirus Infections and Treatments
University of Miami
2015-2024
University of Miami Health System
2021-2024
Prevent Blindness
2011-2023
The California Eye Institute
2011-2023
Regeneron (United States)
2023
Boehringer Ingelheim (United Kingdom)
2023
Association for Research in Vision and Ophthalmology
2023
Carl Zeiss (Germany)
2023
Miami Dermatology and Laser Institute
2011-2022
Allergan (Ireland)
2019-2022
Adipose tissue-derived "stem cells" have been increasingly used by "stem-cell clinics" in the United States and elsewhere to treat a variety of disorders. We evaluated three patients whom severe bilateral visual loss developed after they received intravitreal injections autologous adipose at one such clinic States. In these patients, last documented acuity on Snellen eye chart before injection ranged from 20/30 20/200. The patients' was associated with ocular hypertension, hemorrhagic...
An independent Safety Review Committee (SRC), supported by Novartis Pharma AG, analyzed investigator-reported cases of intraocular inflammation (IOI), endophthalmitis, and retinal arterial occlusion in the phase 3 HAWK HARRIER trials brolucizumab versus aflibercept neovascular age-related macular degeneration (nAMD).A post hoc analysis a subset data from two 2-year, double-masked, multicenter, active-controlled randomized (NCT02307682, NCT02434328).Patients (N = 1817) with untreated, active...
There is no treatment available for vision loss associated with advanced dry age-related macular degeneration (AMD) or geographic atrophy (GA). In a pilot, proof of concept phase 2 study, we evaluated ciliary neurotrophic factor (CNTF) delivered via an intraocular encapsulated cell technology implant the GA. We designed multicenter, 1-y, double-masked, sham-controlled dose-ranging study. Patients GA were randomly assigned to receive high-or low-dose sham surgery. The primary endpoint was...
To assess the rate of infectious endophthalmitis and to describe clinical microbiological features eyes that develop clinically suspected after an intravitreal injection vascular endothelial growth factor antagonists.The medical records patients undergoing injections anti-vascular agents from January 1, 2005, through December 31, 2010, at a single university referral center associated satellite clinics were retrospectively analyzed determine injections.Twelve cases (11 patients) identified...
In Brief Purpose: To describe the appearance of acute syphilitic posterior placoid chorioretinitis, a rare ocular manifestation syphilis, on spectral domain optical coherence tomography (SD OCT) both before and after treatment. Methods: Ophthalmic examination imaging studies 30 eyes 19 confirmed cases were analyzed at time presentation each follow-up visit. Patients with SD OCT fluorescein angiography presentation, least three documented visits initiation therapy, included in study. Standard...
To localize the various levels of abnormalities in multiple evanescent white dot syndrome by comparing "en face" optical coherence tomography (OCT) and OCT angiography with conventional imaging modalities.In this retrospective case series, multimodal was performed 9 retinal centers on 36 patients included widefield fundus autofluorescence (FAF), fluorescein (FA), indocyanine green angiography, B-scan C-scan enhanced depth spectral domain OCT. Optical also at level superficial deep capillary...
In Brief Purpose: To evaluate and characterize multiple evanescent white dot syndrome abnormalities with modern multimodal imaging modalities. Methods: This retrospective cohort study evaluated fundus photography, fluorescein angiography, indocyanine green optical coherence tomography, enhanced depth short-wavelength autofluorescence, near-infrared autofluorescence. Results: Thirty-four patients mean age of 28.7 years were studied (range, 14–49 years). Twenty-six women, eight men. Initial...
The purpose of the current study was to analyze risk factors, clinical features, and treatment outcomes in patients with endogenous fungal endophthalmitis yeast mold infections. For this retrospective consecutive case series, microbiologic records were reviewed identify all intraocular culture-proven treated at a single institution between January 1, 1990 December 31, 2011. Sixty-seven eyes 53 identified; 51 39 had positive cultures for 16 14 molds. Patients molds as causative organism...
To describe the epidemiology of patients with infectious scleritis and identify factors associated poor visual prognosis.Retrospective review inciting factors, causative organisms, outcomes scleritis.Fifty-five (56 eyes) confirmed were included. The median time from event to symptoms was 1.9 months. Eyes a history pterygium surgery had longer development (median 49 months, range 0-183) compared those glaucoma, cataract, retina 1.0-1.6 months; P = 0.001). Fungal, nocardial, mycobacterial...
BACKGROUND AND OBJECTIVE: To assess the incidence and outcomes of infectious endophthalmitis after intravitreal injections anti-vascular endothelial growth factor (anti-VEGF) agents. PATIENTS METHODS: Patient records at Bascom Palmer Eye Institute (BPEI) from January 1, 2005, through December 31, 2014, were reviewed. The largest commercial claims encounters database in U.S. (MarketScan) was utilized to calculate population-based rate for 2011 2013. RESULTS: anti-VEGF 2013 391/740,757...
To describe the clinical and pathologic characteristics of a case retinal vasculitis vitritis following brolucizumab administration subsequent ranibizumab treatment.