Xiaojie Li

ORCID: 0000-0003-2202-6247
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About
Contact & Profiles
Research Areas
  • Nanopore and Nanochannel Transport Studies
  • Ion-surface interactions and analysis
  • Fuel Cells and Related Materials
  • Bone Tissue Engineering Materials
  • Graphene research and applications
  • Advancements in Semiconductor Devices and Circuit Design
  • Dental Implant Techniques and Outcomes
  • Advanced Combustion Engine Technologies
  • Combustion and Detonation Processes
  • Microfluidic and Capillary Electrophoresis Applications
  • Nanoparticle-Based Drug Delivery
  • Advanced biosensing and bioanalysis techniques
  • Advanced Battery Technologies Research
  • Phase Equilibria and Thermodynamics
  • Nanoplatforms for cancer theranostics
  • Nonlinear Optical Materials Studies
  • Chromium effects and bioremediation
  • Carbon and Quantum Dots Applications
  • Calcium Carbonate Crystallization and Inhibition
  • Endodontics and Root Canal Treatments
  • Geochemistry and Geochronology of Asian Mineral Deposits
  • Nanofabrication and Lithography Techniques
  • Graphene and Nanomaterials Applications
  • Environmental remediation with nanomaterials
  • Nuclear Materials and Properties

North University of China
2024

Zhejiang University
2019-2023

Chenzhou First People's Hospital
2023

Qufu Normal University
2023

University of Tsukuba
2023

Huazhong University of Science and Technology
2022

Tianjin International Joint Academy of Biomedicine
2022

Sun Yat-sen University
2014-2021

Third Affiliated Hospital of Sun Yat-sen University
2021

Shaanxi University of Science and Technology
2020

Titanium alloys with various porous structures can be fabricated by advanced additive manufacturing techniques, which are attractive for use as scaffolds bone defect repair. However, modification of the scaffold surfaces, particularly inner is critical to improve osteointegration these scaffolds. In this study, a biomimetic approach was employed construct polydopamine-assisted hydroxyapatite coating (HA/pDA) onto Ti6Al4V electron beam melting method. The surface characterized field emission...

10.1021/acsami.5b00331 article EN ACS Applied Materials & Interfaces 2015-02-25

Direct use of chemotherapy drugs in the treatment gastric cancer often leads to systemic side effects and unsatisfied therapeutic efficacy due lack tumour-targeting ability. The excellent properties nanoparticles make them good tools provide more options for targeted delivery chemotherapeutic drugs. Herein, we developed a novel nanomedicine (GOQD-ICG-CS-6@HM nanoparticles, GIC@HM NPs), which employed graphene oxide quantum dots (GOQDs) co-load photosensitizer indocyanine green (ICG) drug...

10.1080/1061186x.2022.2162060 article EN Journal of drug targeting 2023-01-17

This experimental work studies the translocation of bovine serum albumin (BSA) proteins through MoS2 nanopores. A simple method device fabrication is developed based on dry-transfer exfoliated membranes and subsequent TEM drilling, yielding nanopores a few monolayers thick diameters as small ∼11 nm. The current-voltage relation low-frequency current noise devices are characterized. Typical BSA signals that possibly correspond to various orientations observed in devices, exhibiting enhanced...

10.1063/1.5128499 article EN Applied Physics Letters 2019-11-25

Solid-state nanopores play an important role in sensing single-biomolecules such as DNA and proteins. However, ultra-short translocation time hinders from acquiring more detailed information about biomolecules, further applications sequencing molecular structure analysis are limited. Related studies have shown that MoS2 has no obvious impediment to biomolecule while graphene may cause obstacles this process. By combining these two-dimensional materials, might slow the passage. Herein, we...

10.1039/d2nr04485d article EN Nanoscale 2022-11-16

We propose and fabricate solid-state nanopore devices that monolithically integrate solution-gated, vertical thin-film transistors (TFTs) inside the nanopores for charge-based sensing of translocating biomolecules. The TFTs consist zinc oxide semiconductor channels aluminum gate dielectrics, which are both conformally deposited along inner surfaces via atomic layer deposition. resultant TFT channel lengths diameters reach ∼10 nm range. In translocation experiments using λ-DNAs or bovine...

10.1021/acsnano.1c01042 article EN ACS Nano 2021-05-27

Spherical nanocrystal of apatite has been proved to be beneficial for osteoblast growth. Two apatites with spherical morphology were prepared in this study by chemical wet method and further sintering process. SEM exhibited that both had morphology. The crystal size was approaching each other. XRD showed the separately hydroxyapatite tricalcium phosphate phases. cellular biocompatibility evaluated osteoblasts these two nanocrstal apatites. MTT result indicated a higher cell proliferation...

10.1166/jnn.2016.10940 article EN Journal of Nanoscience and Nanotechnology 2016-02-10

Abstract Excessively-long translocation events of single DNAs are experimentally observed using a small nanopore. Solid-state Nano pores on SiNx membranes with pore diameters less than 5nm fabricated via Transmission Electron Microscopy. The testing system is set up based patch-clamp and Lab-on-Chip, experiments Lambda conducted. Stable current traces molecular achieved. Statistical analysis under various cross-membrane voltages shows typical characteristics pores, including event rates,...

10.1088/1755-1315/632/5/052072 article EN IOP Conference Series Earth and Environmental Science 2021-01-01

Nanopores incorporating electrical gates made of ITO material have highly-desired potential electrically modulating the translocation process biomolecules. In this work, we report our experimental study such devices under condition no gate biases being applied. This baseline characterization is to demonstrate their suitability for sensing. The nanopore electrodes are fabricated by TEM drilling, yielding ~10 nm pore sizes. dsDNA experiments, as well noise characterization, conducted using...

10.1109/nems51815.2021.9451481 article EN 2021-04-25

Mos <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> nanopores have recently been demonstrated to be capable of detecting translocation proteins. In this work, we further investigate the effect MoS nanopore size on process. The are fabricated using TEM drilling that yields diameters ~10 nm and ~20 nm. We use these detect bovine serum albumin (BSA) proteins analyze signal statistics as well shape individual signals. It is found larger can...

10.1109/nems51815.2021.9451432 article EN 2021-04-25

MoS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> nanopore devices as a new tool of biomolecule sensing recently have shown its advantages in single protein molecules detection with higher signal-noise-ratio. In this work we further investigate the types and configurations translocation signals native Bovine Serum Albumin through nanopores various pore sizes ~10 nm ~20 drilled by transmission electronic microscope. Using electrical...

10.1109/nems54180.2022.9791157 article EN 2022-04-14

MoS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -graphene heterostructure nanopores have shown the potential of detecting single protein molecules with high spatial resolution and slow translocation speed. In this work, we use new type nanopore to identify different including bovine serum albumin (BSA) Immunoglobulin G (IgG). The are drilled by FIB TEM diameter ~12 nm. statistical single-signal analyses conducted. results demonstrate...

10.1109/nems57332.2023.10190969 article EN 2023-05-14
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