A5082325917- Sepsis Diagnosis and Treatment
- Immune Response and Inflammation
- Inflammasome and immune disorders
- Venous Thromboembolism Diagnosis and Management
- Platelet Disorders and Treatments
- IL-33, ST2, and ILC Pathways
- Atrial Fibrillation Management and Outcomes
- Inflammatory Biomarkers in Disease Prognosis
Sichuan University
2023-2025
West China Hospital of Sichuan University
2023-2025
Background Autoimmune diseases exhibit heterogenous dysregulation of pro-inflammatory or anti-inflammatory cytokine expression, akin to the pathophysiology sepsis. It is speculated that individuals with autoimmune may have an increased likelihood developing sepsis and face elevated mortality risks following septic events. However, current observational studies not yielded consistent conclusions. This study aims explore causal relationship between using Mendelian randomization (MR) analysis....
Although platelets have been linked to inflammatory development in sepsis, knowledge on their role as an indicator sepsis treatment is scarce. Here, we investigated the association between time-dependent changes platelet counts with mortality rates reveal of therapy.A retrospective cohort study.We screened Medical Information Mart for Intensive Care (MIMIC-IV), a public database comprising data from critical care subjects at Beth Israel Deaconess Center (BIDMC) Boston, Massachusetts, USA.A...
Abstract Background Sepsis is one of the risk factors for deep vein thrombosis (DVT). However, studies on DVT in critically ill patients with sepsis are limited, and no specific assessment tool available evaluating this population. We aimed to determine develop a simple nomogram vulnerable Methods In retrospective observational study, using Sepsis-3 criteria, who were admitted intensive care unit (ICU) West China Hospital Sichuan University from January 2015 May 2022, enrolled. Patients...
Abstract Background Sepsis is a prominent reason for admission in the Intensive Care Unit (ICU), where certain autoimmune diseases exhibit dysregulation of cytokines similar sepsis. Existing research suggests that individuals with disorders are more susceptible to developing sepsis and experiencing higher mortality rates. This highlights need precise strategies. However, current observational studies provide conflicting conclusions regarding relationship between conditions Therefore, we...