- Ion-surface interactions and analysis
- Nuclear Physics and Applications
- ZnO doping and properties
- Integrated Circuits and Semiconductor Failure Analysis
- Semiconductor materials and devices
- Electronic and Structural Properties of Oxides
- Diamond and Carbon-based Materials Research
- Silicon and Solar Cell Technologies
- Gas Sensing Nanomaterials and Sensors
- Ga2O3 and related materials
- Polymer Nanocomposite Synthesis and Irradiation
- Gold and Silver Nanoparticles Synthesis and Applications
- Graphene research and applications
- Copper-based nanomaterials and applications
- Transition Metal Oxide Nanomaterials
- Nuclear physics research studies
- Conducting polymers and applications
- Particle accelerators and beam dynamics
- Quantum Dots Synthesis And Properties
- Magnetic and transport properties of perovskites and related materials
- Folate and B Vitamins Research
- Nuclear Materials and Properties
- GaN-based semiconductor devices and materials
- Semiconductor materials and interfaces
- Chalcogenide Semiconductor Thin Films
Inter-University Accelerator Centre
2016-2025
Indian Institute of Technology Gandhinagar
2025
Banasthali University
2025
Sharda University
2024
Tata Motors (India)
2024
University Hospitals Bristol and Weston NHS Foundation Trust
2023
University of Delhi
2020-2023
University Hospitals Bristol NHS Foundation Trust
2023
Institute of Physics, Bhubaneshwar
2021
Indian Institute of Technology Roorkee
2021
The Structure-Function Linkage Database (SFLD, http://sfld.rbvi.ucsf.edu/) is a manually curated classification resource describing structure-function relationships for functionally diverse enzyme superfamilies.Members of such superfamilies are in their overall reactions yet share common ancestor and some conserved active site features associated with functional attributes as partial reaction.Thus, despite different functions, members these 'look alike', making them easy to misannotate.To...
Auxin regulates every aspect of plant growth and development. Previous genetic studies demonstrated that YUCCA (YUC) flavin-containing monooxygenases (FMOs) catalyze a rate-limiting step in auxin biosynthesis YUCs are essential for many developmental processes. We proposed convert indole-3-pyruvate (IPA) to indole-3-acetate (IAA). However, the exact biochemical mechanism has remained elusive. Here we present characterization recombinant Arabidopsis YUC6. Expressed purified from Escherichia...
The study of mechanistically diverse enzyme superfamiliescollections enzymes that perform different overall reactions but share both a common fold and distinct mechanistic step performed by key conserved residueshelps elucidate the structure−function relationships enzymes. We have developed resource, linkage database (SFLD), to analyze these relationships. Unique SFLD is its hierarchical classification scheme based on linking specific partial (or other chemical capabilities) are at...
Elevated levels of homocysteine, a sulfur-containing amino acid, are correlated with increased risk for cardiovascular diseases and Alzheimers disease neural tube defects. The only route the catabolic removal homocysteine in mammals begins pyridoxal phosphate- (PLP-) dependent β-replacement reaction catalyzed by cystathionine β-synthase. enzyme has b-type heme unusual spectroscopic properties but as yet unknown function. human modular organization can be cleaved into an N-terminal catalytic...
Herein, we present defect-induced photoluminescence behavior of Ga-doped ZnO (GZO) thin films with varying doping (Ga) concentrations and energetic ion irradiation. The were prepared by a sol-gel spin-coating method. Micro-photoluminescence (μ-PL) was carried out to investigate the defect-related emission variation concentration PL spectra revealed that all showed near-band-edge (NBE) along broad visible band, consisting violet, blue, green, yellow bands. intensity these bands found be...
Abstract Antiferromagnetic insulators are a ubiquitous class of magnetic materials, holding the promise low-dissipation spin-based computing devices that can display ultra-fast switching and robust against stray fields. However, their imperviousness to fields also makes them difficult control in reversible scalable manner. Here we demonstrate novel proof-of-principle ionic approach spin reorientation (Morin) transition reversibly common antiferromagnetic insulator α-Fe 2 O 3 (haematite) –...
Paroxysmal non-kinesigenic dyskinesia (PNKD) is a rare autosomal dominant movement disorder triggered by stress, fatigue or consumption of either alcohol caffeine. Attacks last 1–4 h and consist dramatic dystonia choreoathetosis in the limbs, trunk face. The disease associated with single amino acid changes (A7V A9V) PNKD, protein unknown function. Here we studied stability, cellular localization enzymatic activity PNKD cultured cells transgenic animals. N-terminus wild-type (WT) long...
Structural and biochemical constraints force some segments of proteins to evolve more slowly than others, often allowing identification conserved structural or sequence motifs that can be associated with substrate binding properties, chemical mechanisms, molecular functions. We have assessed the functional imposed by cofactors on evolution new functions in a superfamily flavoproteins characterized two-dinucleotide domains, "two dinucleotide domains" (tDBDF) superfamily. Although these...
Yttrium doped hafnia (Y-doped HfO2) thin film based devices have recently shown their potential for advanced nanoelectronics applications. Here, we report the fabrication of device-grade Hf(1−x)YxO2 (x = 0, 0.10, and 0.20) films on both Si(100) platinized silicon substrates using an optimized Nd:YAG pulsed laser deposition system, wherein detailed structural compositional characterizations were carried out to establish a structural-dielectric property correlation. The capacitance-frequency...
Abstract Breast cancer remains the second most common cause of cancer‐related deaths in women worldwide, with ≈70% cases linked to overexpression Estrogen Receptor (ERα). Existing imaging tools often fail reliably differentiate between ER‐positive and ER‐negative cells. To address this limitation, two novel fluorescent probes, E2N E2R , are synthesized by conjugating estradiol styryl rhodamine‐based fluorophores using click chemistry. These probes characterized their photophysical...
Abstract Antiperovskite manganese nitrides have intriguing magnetic and electronic properties that are not well understood. Just as their perovskite oxide counterparts, they expected to display tunable through epitaxial strain engineering, which has barely been explored yet. Here, three notable contributions made the understanding tuning of these fascinating materials, focusing on Mn 3 NiN. First, combining X‐ray spectroscopy measurements first‐principles calculations, an unusually large...
Lysosomes and the endoplasmic reticulum (ER) are critical for cellular homeostasis signaling. New red-emitting probes enable stable, low-toxicity imaging of these organelles, advancing studies their dynamics interactions.