A5090450459- Retinal and Macular Surgery
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Vascular Malformations Diagnosis and Treatment
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Ocular Infections and Treatments
- Corneal surgery and disorders
- Connective tissue disorders research
- Ophthalmology and Eye Disorders
- Retinoids in leukemia and cellular processes
- Ocular Oncology and Treatments
- Concrete Corrosion and Durability
- Pain Management and Opioid Use
- Ocular Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Intracerebral and Subarachnoid Hemorrhage Research
- Medical Imaging and Pathology Studies
- Anesthesia and Pain Management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Melanoma and MAPK Pathways
- Facial Trauma and Fracture Management
ZNA Middelheim Hospital
2016-2024
Rotterdam Eye Hospital
2008-2019
Combined Ophthalmic Research Rotterdam
2019
ViteroRetinal Surgery
2015
Erasmus University Rotterdam
2010
KU Leuven
1996-1998
University of Pittsburgh Medical Center
1996
Rega Institute for Medical Research
1996
Introduction: A massive suprachoroidal haemorrhage (SCH) is a devastating complication with significant morbidity and poor visual anatomic outcome. Conventional management to observe for 7-14 days before surgical drainage. However, permanent structural changes in the retina can occur within this timeframe. Suprachoroidal injection of recombinant tissue plasminogen activator may speed up clot breakdown aid early We present case series macula-involving SCH treated drainage aided by r-tPA. Case...
Purpose.: To investigate COL9A1 in two families suggestive of autosomal recessive Stickler syndrome and to delineate the associated phenotype. Methods.: The probands consanguineous were evaluated for homozygosity using SNP microarray one haplotype analysis other. Subsequently, entire open reading frame was analyzed by DNA sequencing all members respective families. Several family investigated dysmorphic features as well ophthalmic, audiologic, radiologic abnormalities. Results.: A novel...
We previously hypothesized a causal relationship between vitreoschisis-induced vitreous cortex remnants (VCR) and the development of proliferative vitreoretinopathy (PVR). This study aims to substantiate this association through histopathological analysis surgical specimens in support strategies improve therapeutic outcomes.A descriptive, prospective, non-consecutive case series. Histopathological immunohistochemical analyses were performed on membranes removed from peripheral retinal...
<b>Aims:</b> To study the clinical properties of double vital staining in premacular fibrosis, facilitating complete removal all epiretinal tissue. <b>Methods:</b> In a two step surgery, pucker was removed after with trypan blue, whereafter inner limiting membrane peeled infracyanine green. <b>Results:</b> 30 patients, separate layer and were from macular area. Pathological examination showed different histological layers. An increased visual acuity measured 26 slightly decreased one...
Blood–retinal barrier breakdown secondary to retinal detachment and repair is a factor in the pathogenesis of proliferative vitreoretinopathy (PVR). We wished investigate whether an estimated 700 1000 ng/ml subretinal dexamethasone concentration at time surgery would decrease blood–retinal postoperatively. Prospective, placebo-controlled, double blind clinical trial. In 34 patients with rhegmatogenous scheduled for conventional scleral buckling surgery, subconjunctival injection 0.5 ml...
Abstract Purpose We aimed to determine whether intravitreal dexamethasone as an adjuvant antibiotics is beneficial in the treatment of suspected bacterial endophthalmitis after cataract surgery. Methods Randomized, placebo‐controlled superiority trial three tertiary referral centres Netherlands. Patients with within 6 weeks surgery were eligible. A diagnostic vitreous biopsy was taken for culture, and patients received injections 400 μ g (without preservatives) or placebo, addition 0.2 mg...
Background: A new technique for visualisation of the vitreous base is described. It uses a standard lightpipe scleral indentation and transillumination. Visualisation using low light levels can be achieved by enhancing Tyndall effect. Discussion: Perfluorocarbon liquid (PFCL) used to confine aqueous environment anterior cavity triamcinolone added increase scatter. The clearly differentiates from PFCL infusion fluid, facilitates trimming base, draining subretinal fluid air/fluid exchange.
Abstract. Purpose: To evaluate the feasibility of two novel ‘heavy’ dye solutions for staining internal limiting membrane (ILM) and epiretinal membranes (ERMs), without need a prior fluid‐air exchange, during macular surgery. Methods: In this prospective nonrandomized multicenter cohort study, high molecular weight dyes ILM‐Blue™ [0.025% brilliant blue G, 4% polyethylene glycol (PEG)] MembraneBlue‐Dual™ (0.15% trypan blue, 0.025% PEG) were randomly used in vitrectomy surgeries disease 127...