- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular and exercise physiology
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac tumors and thrombi
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- Dialysis and Renal Disease Management
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiovascular and Diving-Related Complications
- Cardiovascular Disease and Adiposity
- Peripheral Artery Disease Management
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Cardiac Structural Anomalies and Repair
- Cardiac and Coronary Surgery Techniques
Saints Cyril and Methodius University of Skopje
2011-2025
University Clinic of Traumatology
2008-2020
University of Ss. Cyril and Methodius in Trnava
2014
University Clinical Center of Kosovo
2012
Cambridge University Press
2011
Institute of public health of Republic of Macedonia
2007
Institute for Rheumatic Diseases (Japan)
2005
Abstract Background. Left atrial appendage (LAA) may be a source of thrombi in patients with dilated cardiomyopathy at sinus rhythm. The objectives our study were to assess the prevalence intracardiac left chamber thrombus and/or spontaneous echo contrast and identify clinical echocardiographic predictors for ventricle (LV), atrium (LA), LAA formation, particularly as regard LV, LA, size, heart failure Methods. We included 45 ischemic or idiopathic origin mild moderate systolic dysfunction,...
Objective: To evaluate additional role of left atrial two-dimensional speckle tracking echocardiography in patients with diabetes mellitus type 2, 218 heart failure preserved ventricular ejection fraction divided according to the presence (108 and 110 without) were enrolled study. Methods: Traditional parameters using Doppler imaging measured as expressions diastolic function well peak longitudinal strain contraction echocardiography. Results: Global average significantly lower ( p = 0.002...
Introduction The aim of this prospective study was to evaluate the association between serum magnesium (Mg) and mortality, in particular cause-specific mortality Mg other risk factors hemodialysis (HD) patients. Methods We studied a cohort 185 HD patients receiving thrice-weekly treatment, on dialysate concentration 0.5 mmol/L. stratified 3 patient groups according level Mg: lower (<1.1 mmol/L), intermediate-reference (1.1 <1.3 higher (Mg >1.3 mm/L). Results During 5-year follow-up,...
Ischemic dilated cardiomyopathy offers a favorable terrain for left ventricular (LV) thrombus formation; however, artial appendage (LAA) may be an additional source of thrombi in patients with heart. The main objectives this study were to determine the prevalence LV and LAA chronic ischemic sinus rhythm, as well reveal echocardiographic predictors formation.The included 57 who not under oral anticoagulation therapy. Exclusion criteria with: swallowing problems, acute myocardial infarction,...
BACKGROUND: Elderly population (≥ 65) are more prone to develop acute kidney injury (AKI) compared younger, also elderly with AKI have an increased requirement for dialysis treatment and elevated risk of short-term long-term mortality.AIM: The objectives this study were examine the effect outcomes mortality in patients AKI.MATERIAL AND METHODS: Seventy patients, that filled one criteria definition had hospitalization over 24 hours, enrolled study.RESULTS: median age was 74.28 ± 6.64, mean...
Interatrial septal anomalies, which include atrial defect, patent foramen ovale, and aneurysm, are common disorders among adult patients. Early detection of interatrial anomalies is important in order to prevent haemodynamic consequences and/or thromboembolic events. Electrocardiogram offers some clues that should serve as hints for abnormalities. The aim our study was analyse the septum by transoesophageal echocardiography patients with electrocardiogram signs right bundle branch block...
Background: Chronic infections in CHD are due to one or both of the organisms Chlamydia pneumoniae and Helicobacter pylori.Aim: To examine association between serum markers pylori infection myocardial damage.in patients with acute coronary syndrome (ACS), chronic artery disease (CAD) in-control group.Material methods: Sera were taken from a total 153 subjects.Subjects divided three groups: 64 ACS; 53 CAD group 35 conditionally healthy individuals.Analysis patients' sera for IgG antibodies H....
INTRODUCTION: Although strict selection criteria are used to select patients for cardiac resynchronisation therapy, up 30% of do not have a positive clinical response.PATIENTS: A total 102 consecutive who had biventricular pacemaker/defibrillator (CRT-P or CRT-D) implanted were enrolled in this prospective observational study.RESULTS: During the average follow-up period 24.3 months 5 died and 17 (16.7%) hospitalised with symptoms heart failure; 75 (73.5%) responders based on previously...
AIM: This prospective study was designed to evaluate the changes in left ventricular (LV) systolic function after coronary artery bypass grafting (CABG) patients with both normal and abnormal pre-operative function.
 METHODS: During period from October 2017 2018, forty-seven consecutive undergoing CABG were enrolled this study. Transthoracic echocardiography performed within 1 week before as well 4 6 months surgery. All measurements made by a single experienced investigator.
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The aim of the study was to evaluate prevalence carotid artery disease in type 2 diabetes patients with coronary disease, and establish influence metabolic factors on its occurrence. In all, 145 (aged 59.85±8.43 years, duration 8.89±6.29 years) were randomly selected a cross-sectional study. Carotid ultrasound used for evaluation presence plaque (CP) stenosis (CS). A logistic regression model constructed define risk - arterial hypertension, systolic blood pressure, weight, waist hip ratio,...
BACKGROUND: Triad of childhood vesicoureteral reflux (VUR), urinary infection (UTI) and renal scarring might initiate potentially serious consequences that lead to dysfunction manifested at the second or third decade life.
 AIM: To identify risk factors predictive for in adults with primary VUR after long-term follow-up.
 METHODS: We evaluated records 101 children (94.1% female, 5.9% male) a median age 5.2 ± 2.3 years (1-12 years), suffering from UTI VUR. The patients were...
The impact of serum uric acid (UA) on morbidity and mortality in hemodialysis (HD) patients is quite controversial relation to the general population. aim this study was evaluate association UA with both left ventricular hypertrophy (LVH) HD patients.This longitudinal enrolled 225 prevalent who were classified into three groups according their follow-up-averaged (FA-UA) levels: low FA-UA (FA-UA <400 µmol/L), intermediate/reference between 400 450 µmol/L) high >450 µmol/L). Echocardiography...
BACKGROUND: Percutaneous transcatheter closure (PTC) of patent foramen ovale (PFO) is implicated in cryptogenic stroke, transitional ischemic attack (TIA) and treatment a migraine.AIM: Our goal was to present our experience the interventional PFO, as well evaluate short mid-term results patients with closed PFO.MATERIAL AND METHODS: Transcatheter PFO performed 52 (67.3% women, mean age 40.7 ± 11.7 years). Patients were interviewed for subjective grading intensity headaches before after...
<i>Background:</i> The ability of brain natriuretic peptide (BNP) together with other traditional and nontraditional risk factors to predict cardiovascular (CV) mortality in hemodialysis (HD) patients has not been well established. aim this prospective study was determine the predictive cutoff values baseline measurement BNP along known CV disease all-cause HD patients. <i>Methods:</i> concentration before measured 125 prevalent (age 53.0 ± 13.5 years, vintage 75.2...
Thromboembolic events are a frequent cause of mortality in patients with congestive heart failure. The aim or study was to evaluate the relationship left ventricular end diastolic diameter (LVEDD) atrial (LA) size and appendage (LAA) dilated cardiomyopathy sinus rhythm, as well determine prevalence thrombi LV LA /LAA.This prospective cross-sectional study, conducted from December 2009 until 2011. included 95 rhythm. Patients swallowing problems, acute myocardial infarction,...
The use of a 12-lead electrocardiogram (ECG) in the screening young athletes still has some controversies regarding cost-benefit procedure.We wanted to identify types and frequency ECG changes Republic Macedonia as well its relation age, gender, duration, type sports.The study population included 256 trained amateur who were prospectively examined.The patterns considered normal 19.9% athletes, with common training-related found 48.8%, while abnormal borderline present 6.6% 24.6%...
The purpose of the study was to assess endothelial dysfunction (ED) in type 2 diabetic patients ultrasonographically and estimate correlation ED with glycemia other cardio-metabolic risk factors. 171 patient (age 60.0 + 8.5 years) diagnosed diabetes coronary artery disease (CAD) were randomly included a cross sectional study. B-mode ultrasound system linear transducer 7.5 MHz used for evaluation flow-mediated vasodilation brachial (FMV). FMV presented as change diameter at rest after limb...
The study was aimed to define the predictors for peripheral and carotid revascularization in type 2 diabetic population. In all, 279 patients with diabetes arterial disease were enrolled a cohort longitudinal study. Study population followed up 24 months need performance of or revascularization. Logistic regression analysis conducted identify variables predictive revascularization, when lipid plasma levels, glycemia, hypertension, blood pressures, ankle-brachial index, intima-media...
Purpose: It is a well recognized fact that thromboembolic events are frequent in patients with congestive heart failure. Left atrial appendage (LAA) may be crucial source of thromboembolism dilated cardiomyopathy. The purpose this study was to identify clinical and echocardiographic predictors LAA thrombus sinus rhythm (SR) cardiomyopathy mild moderate systolic dysfunction. Methods: This prospective, cross-sectional conducted on 101 SR ischemic non-ischemic etiology at dysfunction, which...