A5072896182- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Renal Diseases and Glomerulopathies
- Vascular Procedures and Complications
- Renal Transplantation Outcomes and Treatments
- Chronic Kidney Disease and Diabetes
- Renal and Vascular Pathologies
- Vascular anomalies and interventions
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Peripheral Artery Disease Management
- Neurological Complications and Syndromes
- Acute Kidney Injury Research
- Neurological and metabolic disorders
- Vasculitis and related conditions
- Sarcoidosis and Beryllium Toxicity Research
- Muscle and Compartmental Disorders
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Long-Term Effects of COVID-19
- Erythropoietin and Anemia Treatment
- Biomedical Research and Pathophysiology
- Blood donation and transfusion practices
- Gout, Hyperuricemia, Uric Acid
- Ecocriticism and Environmental Literature
- Bone and Joint Diseases
Saints Cyril and Methodius University of Skopje
2018-2025
University Clinic of Traumatology
2024
PHI University Psychiatric Clinic - Skopje
2020-2024
Aarhus School of Architecture
2023
Creative Commons
2022
The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with ESKD. This paper is a summary of the ERA Annual Report 2020, also including comparisons among primary renal disease (PRD) groups.Data were collected from 52 national and regional registries 34 countries bordering Mediterranean Sea: 35 18 providing individual level 17 aggregated data. Using this data, KRT incidence prevalence, transplantation rates, expected remaining lifetimes...
Data on renal replacement therapy (RRT) for end-stage disease were collected by the European Renal Association (ERA) Registry via national and regional registries in Europe countries bordering Mediterranean Sea. This article provides a summary of 2019 ERA Annual Report, including data from 34 additional age comparisons.Individual patient provided 35 aggregated 17 registries. Using these data, incidence prevalence RRT, kidney transplantation activity survival probabilities calculated.In 2019,...
The European Renal Association - Dialysis and Transplant (ERA-EDTA) Registry collects data on kidney replacement therapy (KRT) via national regional renal registries in Europe countries bordering the Mediterranean Sea. This article summarizes 2018 ERA-EDTA Annual Report, describes epidemiology of KRT for failure 34 countries.Individual patient patients undergoing were provided by or aggregated 17 registries. incidence prevalence KRT, transplantation activity survival probabilities these...
ABSTRACT Background The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with end-stage disease (ESKD). This paper is a summary of the ERA Annual Report 2021, including comparison across treatment modalities. Methods Data was collected from 54 national and regional registries 36 countries, which 35 18 countries contributed individual patient 19 aggregated data. Using this data, incidence prevalence KRT, transplantation rates, survival...
ABSTRACT Background The aim of this study was to identify trends in total, deceased donor (DD) and living (LD) kidney transplantation (KT) rates European countries. Methods Renal Association (ERA) Registry the Global Observatory on Donation Transplantation (GODT) databases were used obtain number KTs individual countries between 2010 2018. General population counts obtained from Eurostat or national bureaus statistics. KT rate per million (p.m.p.) average annual percentage change (APC)...
Abstract Sarcoidosis is a chronic, multisystem, inflammatory granulomatous disease that affects multiple organs in the body, but mostly lungs and lymph glands. Hypercalcemia renal affection are rarely initial presenting features, absence of pulmonary symptoms, diagnosis sarcoidosis those patients could be diagnostic challenge. A case-patient with presented elevated serum calcium creatinine levels. Renal biopsy showed nephrocalcinosis chronic fibrosing interstitial nephritis. The extensive...
BACKGROUND: An Arteriovenous fistula (AVF) is a creation of the natural blood vessels. It “gate life” for patients on hemodialysis. AIM: The study aimed to analyze predictors primary failure AVF such as gender, age, number and location AVF, renal disease in with chronic kidney (CKD) stage 4/5.MATERIAL AND METHODS: medical records 178 created arteriovenous fistulae CKD 4/5, were retrospectively studied. Primary was defined thrombosis or inability cannulation within 3 months. Adequate...
Peritoneal dialysis-related peritonitis remains the major complication and primary challenge to long-term success of peritoneal dialysis (PD). The study aimed analyze rate, cause, outcomes, association with survival patients on dialysis. Patient data were collected retrospectively from medical charts. A total 96 received in PD center 1 January 1999 31 December 2018. Episodes (n=159) registered 54 (56.3%) patients. population was divided into two groups, a group (n=54) who experienced free...
BACKGROUND: Carnitine palmitoyltransferase II deficiency (CPT II) is an autosomal recessive disorder and the most common inherited of mitochondrial long-chain fatty acid oxidation, characterised by attacks myalgia myoglobinuria. The “classic” myopathic form occurs in young adults recurrent episodes rhabdomyolysis triggered prolonged exercise, fasting or febrile illness.CASE PRESENTATION: We present a case 22-year-old Caucasian male admitted to our hospital with fever, dyspnea, fatigue, dark...
Abstract Membranoproliferative glomerulonephritis (MPGN) is a rare glomerular disease characterized by mesangial hypercellularity and thickening of the basement membrane (GBM). MPGN can be idiopathic or associated with malignancy, systemic immune complex disorders chronic infections. It has rarely been solid organ tumors, such as lung, gastric, breast prostate cancer. We report patient coexisting colorectal carcinoma. A 48-year-old man presented anemia, loss weight, hypertension, nephrotic...
Abstract An arteriovenous fistula (AVF) remains the best choice of vascular access (VA) for hemodialysis (HD). The aim study was to determine factors associated with achievement adequate blood flow (BF) AVFs at 4th week after creation. Created in 63 patients chronic kidney disease (CKD) stage 4/5 and CKD 5 on (CKD5D) were analyzed a prospective study. Doppler ultrasound (DUS) used measuring diameter radial artery, brachial artery cephalic vein before AVF BF calculated by DUS creation defined...
The number of patients treated with hemodialysis (HD) in Europe is more than half a million and this increases annually. arteriovenous fistula (AVF) the vascular access (VA) first choice, but clinical outcome still poor. A consistent AVFs fails to reach desired blood flow rate for HD treatment, while some have too high risk cardiac complications. Despite skill surgeons possibility use Ultrasound investigation mapping arm vasculature, it not possible predict volume that will be obtained after...
The impact of serum uric acid (UA) on morbidity and mortality in hemodialysis (HD) patients is quite controversial relation to the general population. aim this study was evaluate association UA with both left ventricular hypertrophy (LVH) HD patients.This longitudinal enrolled 225 prevalent who were classified into three groups according their follow-up-averaged (FA-UA) levels: low FA-UA (FA-UA <400 µmol/L), intermediate/reference between 400 450 µmol/L) high >450 µmol/L). Echocardiography...
X-linked Alport syndrome (AS) caused by hemizygous disease-causing variants in COL4A5 primarily affects males. Females with a heterozygous state show diverse phenotypic spectrum ranging from microscopic hematuria to end-stage kidney disease (ESKD) and extrarenal manifestations. In other diseases, skewed X-inactivation leads preferential silencing of one X-chromosome thus can determine the phenotype females. We aimed correlation between blood urine-derived renal cells clinical females variant...
University Clinic for Nephrology, Faculty of Medicine, Ss. Cyril and Methodius in Skopje, North Macedonia aCorrespondence: Nikola Gjorgjievski Hospital NephrologyVascular Access Department Mother Teresa 1000 MACEDONIA, THE FORMER YUGOSLAV REPUBLIC OF [email protected]
Emphysematous pyelonephritis (EPN) is a rare, severe, spontaneous gas-forming infection of renal parenchyma and its surrounding areas. EPN was detected in diabetic patients. A 49-year-old female with type I diabetes mellitus presented severe thrombocytopenia, acute kidney injury (AKI) need haemodialysis treatment. She had impaired liver function tests, active urine sediment, indicating upper urinary tract suspected sepsis. The contrast enhanced CT scan the abdomen showed multiple areas air...
Physiologically, GFR level should be stable up to the end of fifth decade life. When measured more frequently, wide dispersion results have been seen, but, after 5th is expected reduce by 1ml/min/1,73m2 yearly. The aim this study was calculate change estimated on annual and its correlations in healthy individuals. This a retrospective observational 62 subjects during 6 years. Demographical characteristics as gender, age, BMI, obesity (defined BMI above 30kg/m2) creatinine were obtained from...
Introduction Fabry disease is a rare X-linked lysosomal storage disorder caused by α-galactosidase A (α-Gal A) deficiency. Reduced or absent enzyme activity causes progressive accumulation of globotriaosylceramide (Lyso-Gb3) in various cells throughout the body to trigger inflammation and fibrosis. Case description We present first familial case Disease North Macedonia identified based on clinical manifestations confirmed through enzyme, biomarker, genetic tests. The index family was...
Abstract Introduction Kidney replacement therapy (KRT) by dialysis or kidney transplantation represents the main treatment modalities for patients with failure. Here we evaluate trends in taking care of such North Macedonia from 2015 through 2020. Methods The were analyzed according to age, sex, primary disease, and modality. They further subdivided into 3 groups: Group 1, prevalent patients; 2, incident analysis starting at day 1 KRT; 3, 91 KRT. Results study included 10,395 person-years,...
Abstract Diabetic kidney disease (DKD) is a significant and growing global health concern, affecting substantial proportion of individuals with diabetes mellitus. This position paper Scientific societies endocrinologists, nephrologists cardiologists has been consensually brought at couple mutual meetings, aiming to synthesize current knowledge on screening, diagnosis staging DKD, emphasizing the need for an early detection intervention in order prevent progression end-stage renal (ESRD). The...
BACKGROUND: Excess mortality is defined as above what would be expected based on the non-crisis rate in population of interest.
 AIM: In this study, we aimed to access weather coronavirus disease (COVID)-19 pandemic had impact in-hospital during first 6 months year and compare it with data from previous years.
 METHODS: A retroprospective study was conducted at University Clinic Nephrology Skopje, Republic Macedonia. In-hospital rates were calculated for half (01.01–30.06) 2015...
The antiphospholipid syndrome is a systemic autoimmune disease defined by recurrent vascular and/or obstetrical morbidity that occurs in patients with persistent antibodies.A patient on hemodialysis primary presented access thrombosis, complications, and positive lupus anticoagulant. had multiple arteriovenous fistulas failed due to thrombosis. was one miscarriage at the 7th week of gestation pregnancy complicated pre-eclampsia preterm delivery 28th gestation. A thorough thrombophilia...