Sepideh Khaksar

ORCID: 0000-0003-2251-7329
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About
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Research Areas
  • Cannabis and Cannabinoid Research
  • Neuroscience and Neuropharmacology Research
  • Wound Healing and Treatments
  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Oral health in cancer treatment
  • MicroRNA in disease regulation
  • Biochemical effects in animals
  • Diabetic Foot Ulcer Assessment and Management
  • Pressure Ulcer Prevention and Management
  • Neurological Disease Mechanisms and Treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological Complications and Syndromes
  • Cancer, Hypoxia, and Metabolism
  • Head and Neck Cancer Studies
  • Infant Development and Preterm Care
  • Mesenchymal stem cell research
  • Cardiovascular Health and Disease Prevention
  • Fetal and Pediatric Neurological Disorders
  • Genomics, phytochemicals, and oxidative stress
  • Sirtuins and Resveratrol in Medicine
  • Pharmacological Effects and Toxicity Studies
  • Saffron Plant Research Studies
  • Oral Health Pathology and Treatment
  • Gold and Silver Nanoparticles Synthesis and Applications

Alzahra University
2020-2024

Shahid Beheshti University
2016-2017

Shahid Chamran University of Ahvaz
2011

Abstract Optical intrinsic signal imaging (OISi) method is an optical technique to evaluate the functional connectivity (FC) of cortex in animals. Already, using OISi, FC has been measured time or frequency domain separately, and at frequencies below 0.08 Hz, which not range hemodynamic oscillations are able track fast cortical events, including neurogenic, myogenic, cardiac respiratory activities. In current work, we calculated wavelet coherence (WC) transform OISi series cerebral response...

10.1038/s41598-020-66246-9 article EN cc-by Scientific Reports 2020-06-10

Stroke is a neurological disease, which, in addition to high mortality, imposes many financial and mental burdens on families the society. The main objective of this study was investigate effect cannabidiol (CBD) one major inflammatory pathways cerebral ischaemia.Using stereotaxic surgery, cannula implanted into right lateral ventricle rats. CBD (50, 100, 200 ng/rat; i.c.v.) administrated for five consecutive days. After pretreatment, rats were subjected 60 min middle artery occlusion...

10.1080/02699052.2017.1358397 article EN Brain Injury 2017-09-05

Recent studies demonstrated that cannabidiol had neuroprotective property. There is some evidence about effective role of in reduction ischemic damages. It has been reported infarct size influenced by various factors after MCAO, including inflammatory factors. The aim the present study was to evaluate effect on infarction volume and correlation with tumor necrosis factor receptor 1 (TNFR1), nuclear kappa-light-chain-enhancer activated B cells (NF-κB) expression.Using stereotaxic surgery,...

10.18869/nirp.bcn.8.2.139 article EN cc-by-nc Basic and Clinical Neuroscience Journal 2017-04-01

Oral mucositis (OM), an acute inflammation of the oral cavity, is a common complication in patients undergoing invasive myeloblastic chemotherapy or radiation therapy. 5-fluorouracil (5-FU) one most effective therapeutic drugs, but side effects 5-FU administration OM. Unfortunately, no suitable treatment has been found, so far to control its effects. Studies showed that herbal medicine like Punica granatum var pleniflora (PGP) medicinal properties such as anti-inflammatory and antibacterial...

10.1186/s12906-023-04053-1 article EN cc-by BMC Complementary Medicine and Therapies 2023-07-07

The concept of creativity has many aspect.Whether it is a simple act innovation or grand work genius, and shape the way we live, think, believe.With case studies artists with neurological diseases their experiences disease, review construct creativity, describe neural mechanisms underlying these effects, explain influences art on creativity.In psychology neuroscience, topic great interest, but findings are not always consistent.A difficult domain to study may partly inconsistent when comes...

10.47176/kurmanj.5.1.1 article EN KURMANJ The Journal of Culture Humanities and Social Science 2022-10-20

Background Neuroprotective role of olive and its natural products can introduce them as alternative candidates for the management neurodegenerative diseases including stroke. The present study was designed to evaluate whether pretreatment oil leaf extract attenuate most important destructive processes in cerebral ischemia called excitotoxicity.

10.1080/00207454.2023.2300732 article EN International Journal of Neuroscience 2023-12-28

One of the newest methods to reduce cerebral ischemia damages is cell therapy. The aim this study evaluate effect Sertoli transplantation on ischemia-induced injuries in animal models stroke. Rats were divided into four groups: transplant+ischemia, ischemia, sham, and control. cells separated from other testis rats cultured. Unilateral was performed right striatum by using stereotaxic surgery. For induction brain middle artery occlusion surgery used 14 days after transplantation. By western...

10.22037/ijpr.2020.15574.13189 article EN PubMed 2020-01-01

Stroke, a cerebrovascular disease, has been introduced as the second cause of death and physical disability in world. Recently, cell-based therapy considered by scientific community promising strategy for reducing ischemic damages. The stem cells umbilical cord release growth neurotrophic factors. remarkable properties these are reason why they were selected potential candidate present research.In this study, impact transplanting on injuries resulting from ischemia was investigated. male...

10.1080/01616412.2020.1839698 article EN Neurological Research 2020-11-09

Sertoli cells (SCs) may be a new candidate to decrease ischemic damage due their ability secrete factors that actively protect neurons and inhibit uncontrollable immune responses. Pre‑treatment with these was considered in the current study. SCs were injected into right striatum rats using stereotaxic technique. Ten days after injection, middle cerebral artery occlusion surgery performed. Following procedures, neurological deficit scores, brain edema, blood‑brain barrier integrity, infarct...

10.55782/ane-2022-003 article EN Acta Neurobiologiae Experimentalis 2022-03-31
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