A5016968200- Autism Spectrum Disorder Research
- Child Development and Digital Technology
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Sesame and Sesamin Research
- Cholinesterase and Neurodegenerative Diseases
- Neuroscience of respiration and sleep
- Traditional Chinese Medicine Analysis
- Child Nutrition and Feeding Issues
- Family and Disability Support Research
- Alzheimer's disease research and treatments
- Stress Responses and Cortisol
- Genetics and Neurodevelopmental Disorders
- Animal Vocal Communication and Behavior
- Infant Development and Preterm Care
- Neurological Disease Mechanisms and Treatments
- Biochemical and biochemical processes
- Antioxidants, Aging, Portulaca oleracea
- Neonatal and fetal brain pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Medicinal Plants and Neuroprotection
- Fetal and Pediatric Neurological Disorders
- Neurological Disorders and Treatments
- Advanced Glycation End Products research
Iran University of Medical Sciences
2015-2024
Institute for Cognitive Science Studies
2019-2023
Shahid Beheshti University
2019-2023
Tehran University of Medical Sciences
2021
Aarhus University
2020-2021
Medical University of Ilam
2014
Context: Salvianolic acids are the most abundant water-soluble compounds extracted from herb Salvia miltiorrhiza L. (Lamiaceae) with antioxidant and protective effects.
In recent years studies have shown that early life excessive screen time exposure may significantly contribute to the emergence of social deficits and autistic-like behaviors. However, exact underlying mechanisms optimal treatment strategies are not completely understood, with conflicting results preceding findings. This study investigates effect oxytocin on autism-related behaviors, associated brain structure abnormalities induced by audiovisual stimulation (EAVS) as an model in rats....
Background: Environmental Enrichment (EE) has been suggested as a possible therapeutic intervention for neurodevelopmental disorders such autism. Although the benefits of this method have reported in some animal models and human studies, unknown pathophysiology autism well number conflicting results, urge further examination potential EE Therefore, aim study was to examine effects environmental enrichment on autism-related behaviors which were induced maternal separation (MS) model. Material...
Autism is a neurodevelopmental disorder with complex pathophysiology that affects different areas of the brain. Evidence over past decade indicated role for cerebellum in social skills connection neuropathological changes. In this study, we examined cerebellar plasticity rats exhibited autistic-like behaviors after maternal separation (MS). We showed were associated changes volume size. first time decreased animal model autism, supporting involvement autism.
Parkinson's Disease (PD) presentations comprise frequent movement disorders in the elderly with various symptoms consisting of motor and non-motor complications. Paeonol is a phenolic chemical agent that has shown antioxidant anti-inflammatory effects different promising on metabotropic glutamate receptors (mGluR)- GABAA-mediated neurotransmission. In this research, we tried to show neuroprotective potential paeonol rat PD model induced by intrastriatal 6-hydroxydopamine (6-OHDA).Rats 6-OHDA...
Today, the effect of extreme early-life exposure to digital devices is suggested as a risk factor for neurodevelopmental disorders. However, multitude factors that influence brain development with subsequent behavioural abnormalities have not been fully elucidated. Herein, we simulated in rats by audio and visual stimulation investigated its effects on autism-related behaviours structural alteration. Male rat pups were exposed excessive audio-visual (EAVS) from PND (post-natal day) 12 35,...
Background and Objective: Parkinson's disease (PD) is an age-related neurodegenerative with selective damage of dopaminergic neurons the mesencephalon. L-dihydroxyphenylamine (L-DOPA) therapy currently gold standard maneuver for PD. Due to protective, anti-inflammatory, antioxidant effect sesamin, this study was undertaken assess dose-dependent agent on motor asymmetry induced by intrastriatal injection 6hydroxydopamine in rat. Materials Methods: In experimental research, male Wistar rats...
Adverse environmental experiences during early life are identified as potential concerns for neurodevelopmental disorders including autism spectrum disorder (ASD) with 1% prevalence among populations. Maternal separation (MS) is an animal model that widely used to study long-term behavioral abnormality. To date, a great deal of studies focused on the therapeutic role enrichment (EE) stress consequences inducing anxiety, depression, and learning deficits. However, influence sex effect...
Adverse environmental experiences during early life identified as potential concerns for neurodevelopmental disorders including autism spectrum disorder (ASD) with 1% prevalence among populations.Maternal separation (MS) is an animal model that widely used to study long-term behavioral abnormality.To date, a great deal of studies focused on the therapeutic role enrichment (EE) stress consequences inducing anxiety, depression and learning deficits.However, influence sex effect autisticlike...