- Childhood Cancer Survivors' Quality of Life
- Iron Metabolism and Disorders
- Palliative Care and End-of-Life Issues
- Public Health and Nutrition
- Hemoglobinopathies and Related Disorders
- Edcuational Technology Systems
- Acute Lymphoblastic Leukemia research
- Mental Health and Well-being
- Education and Character Development
- Erythropoietin and Anemia Treatment
- Ethics and Legal Issues in Pediatric Healthcare
- Family and Patient Care in Intensive Care Units
- Child Nutrition and Water Access
- Educational Methods and Media Use
- Infant Health and Development
- Neutropenia and Cancer Infections
- Family Support in Illness
- Family and Disability Support Research
- Data Mining and Machine Learning Applications
- Acupuncture Treatment Research Studies
- Blockchain Technology in Education and Learning
- Nausea and vomiting management
- Methemoglobinemia and Tumor Lysis Syndrome
- Pharmaceutical studies and practices
- Computer Science and Engineering
University of Indonesia
2015-2025
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2015-2025
A national health survey in Indonesia conducted 2013 showed that the prevalence of anemia school-aged children and adolescents tripled from a 2007. Children are particularly susceptible to iron deficiency (IDA) (ID) because their rapid growth puberty. Teenage girls at risk menstrual bleeding. Low socioeconomic status is also strong factor for experiencing deficiency. Studies regarding ID IDA still vary lacking. This study aims describe with low conditions.This cross-sectional two schools...
Background Copy Number Alterations (CNAs) are changes in DNA structure that lead to gain or loss of copies sections the genome. They correlate with unfavorable prognostic outcomes pediatric leukemia, influencing treatment resistance, relapse rates, and overall survival. Identifying high-risk patients a likelihood CNA positivity is essential for understanding its association clinical characteristics laboratory findings. Since routine testing costly, recognizing simple markers predict presence...
Background: Hyperglycaemia is a common side effect of steroid and L-asparaginase combinations, occurring most often during acute lymphoblastic leukemia (ALL) induction phase. To date in Indonesia, it has not been obtained data on the incidence hyperglycemia children with ALL phase how role combinations different type used. The purpose this study to determine phase, knowing difference between prednisone dexamethasone (in combination L-asparaginase) causing relationship other factors related...
Iron deficiency anemia is common in children with end-stage renal disease (ESRD) on long-term hemodialysis receiving erythropoiesis-stimulating agents. One approach to maintain the iron profile and hemoglobin levels maintenance therapy regular low doses of intravenous (IV) after initial repletion therapy; however, evidence for benefits this lacking. This study evaluated effect IV hemodialysis. retrospective cohort included 41 pediatric ESRD patients normal status who underwent at Pediatric...
Objective: Over the past few years, an integrated approach of palliative care (PC) to chronic and/or life-threatening conditions has been widely used. Home-based PC (HBPC) service is developed meet needs patients at home; however, it not used widely. This study aimed determining benefits HBPC for quality life (QoL) and symptoms intensity in Indonesian children with malignancies. Method: A randomized controlled trial was carried out compare between who were given (a three-month home visit)...
Latar belakang. Transfusi darah merupakan pengobatan satu-satunya bagi pasien thalassemia guna mempertahankan kadar hemoglobin darah. Salah satu cara mengurangi kebutuhan adalah dengan melakukan splenektomi. Tujuan.Membandingkan transfusi pra-splenektomi dan pasca-splenektomi. Metode. Studi deskriptif terhadap βdan thalassemia-β/HbE yang dilakukan splenektomi di Pusat Thalassemia Departemen Ilmu Kesehatan Anak, RS Dr Cipto Mangunkusumo tahun 2006-2009. Data dikumpulkan Hb pra-transfusi,...
Background: Iron deficiency anemia (IDA) is one of the major health issues in world, especially developing countries. During adolescence, iron can be caused by a growth spurt, inadequate nutritional intake, parasite infection, and heavy blood loss during menstruation. Regarding importance this issue, we aimed to assess profile adolescent scavengers living slum areas.
 Materials Methods: This was cross-sectional study conducted October 2016 at an alternative school for adolescents...
Background: Iron-induced cardiomyopathy remains the leading cause of mortality in patients with β-thalassemia major. Iron overload cardiomyopathy, which may be reversible through iron chelation, is characterized by early diastolic dysfunction. Amino-terminal pro-brain natriuretic peptide (NT-proBNP) a sensitive biomarker Aim: The aim study to evaluate diagnostic value NT-proBNP as surrogate marker examined magnetic resonance imaging T2-star (MRI T2*). Methods: Sixty-eight major (10–18 years)...
Background and Objectives. Iron-induced cardiomyopathy remains the leading cause of mortality in β-thalassemia major patients. The T2* magnetic resonance imaging (MRI) technique is gold standard for iron load detection, yet it expensive not widely available especially developing countries. Some previous studies showed that QTc interval could be used as an early detection cardiac overload. This study aimed to evaluate diagnostic value a marker overload adolescent beta thalassemia...
Background: One of the most common and troubling side effects chemotherapy in pediatric is chemotherapy-induced nausea vomiting (CINV). Acupuncture a nonpharmacologic approach that has been shown to reduce CINV symptoms 1 minimally invasive modalities can be applied children press needle. This study aimed assess effectiveness needle acupuncture reducing as assessed by Rhodes index nausea, vomiting, retching (RINVR) score cancer patients undergoing chemotherapy. Methods: The design was single...
Latar belakang. Defiseinsi besi (DB) didefinisikan sebagai penurunan total kandungan dalam tubuh yang ditandai dengan turunnya kadar feritin atau saturasi transferin. Gangguan perkembangan neurokognitif timbul akibat DB bersifat permanen. Identifikasi adanya penting untuk memulai terapi mencegah komplikasi jangka panjang.Tujuan. Mengetahui peran Ret-He mendeteksi pada anak dibandingkan pemeriksaan biomarker penanda status lain (feritin, transferin, serum, dan iron binding capacity...
Palliative care in children is used to be only intended for those near end-of-life phase. Ideally, palliative intervention should given since the first time of cancer diagnosis. introduced from beginning treatment by acknowledging that it helps ensure an ongoing focus on quality life (QOL) so still can enjoy their life. Several approaches have been identify with need care.The aim was describe use Paediatric Screening Scale (PaPaS Scale) and its depiction QOL malignancies.A cross-sectional...
Background Hypertension is a rarely recognized complicationof acute lymphoblastic leukemia (ALL). The incidence ofhypertension in ALL patients Indonesia remains unknown,but the most common risk factors are corticosteroid use duringinduction-phase chemotherapy and renal leukemic infiltration.Objective To determine of hypertension childrenwith ALL, to assess for associations high-dose corticosteroids,renal infiltration, hyperleukocytosis hypertension.Methods This was cross-sectional study...
Abstract Background The prevalence of iron deficiency (ID) and anemia (IDA) in children with cancer is not well studied. detection ID IDA using sensitive laboratory tools may facilitate early diagnosis treatment this cohort. In regard, reticulocyte hemoglobin (Ret-He) content serves as a cost-effective measurement that remains unaffected by inflammation, unlike the ferritin test. Aim objective study to analyze role Ret-He diagnostic tool identify functional absolute cancer. Methods We...
Latar belakang. Besi merupakan mineral esensial yang dibutuhkan tubuh untuk menjalankan fungsi fisiologis. Defisiensi besi didefinisikan sebagai penurunan total kandungan dalam ditandai dengan turunnya kadar feritin atau saturasi transferin. Bayi prematur termasuk ke kelompok berisiko terjadinya defisiensi besi.Tujuan. Memberikan bukti ilmiah pemberian suplementasi pada bayi berat badan lahir rendah mencegah besi.Metode. Pencarian literatur instrumen pencari Pubmed dan Cochrane Library bulan...
Kanker merupakan ancaman serius kesehatan masyarakat karena insidens dan angka kematiannya terus meningkat. Penanganan kanker memerlukan kerjasama multidisiplin kedokteran seperti keterlibatan pembedahan, kemoterapi, radiasi, atau kombinasi dintaranya. Kemoterapi sebagai salah satu upaya mengobati umumnya menimbulkan efek samping berupa mual muntah (chemotherapy-induced nausea and vomiting) yang juga dipengaruhi oleh beberapa faktor potensi emetogenik dari regimen sitostatika spesifik...
Background Childhood cancer and its treatment affects not only children’s health, but also families’ psychosocial function, relationship, emotion, quality of life. Several studies in developed countries have been conducted to address this issue using the Family Adaptation Cohesion Scales (FACES) III Situation-Specific Emotional Reaction Questionnaire (SSERQ). Screening problems is crucial as part comprehensive care. Objective To investigate dynamics family functioning, parental...