A5070229191- COVID-19 Impact on Reproduction
- Public Health and Nutrition
- COVID-19 Clinical Research Studies
- Cardiovascular and Diving-Related Complications
- Neutropenia and Cancer Infections
- Graphene and Nanomaterials Applications
- Child Nutrition and Feeding Issues
- Iron Metabolism and Disorders
- Sarcoma Diagnosis and Treatment
- Infant Nutrition and Health
- Educational Curriculum and Learning Methods
- Aortic Disease and Treatment Approaches
- Surgical site infection prevention
- Airway Management and Intubation Techniques
- Menstrual Health and Disorders
- Cancer therapeutics and mechanisms
- Gastrointestinal motility and disorders
- Histone Deacetylase Inhibitors Research
- Genomic variations and chromosomal abnormalities
- Inflammatory Biomarkers in Disease Prognosis
- Acute Myeloid Leukemia Research
- Vaccine Coverage and Hesitancy
- Cardiac and Coronary Surgery Techniques
- SARS-CoV-2 and COVID-19 Research
- Adolescent Health and Behaviors
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2013-2024
University of Indonesia
2016-2024
Indonesian Pediatric Society
2021-2023
BackgroundThe incidence of coronavirus disease 2019 (COVID-19) is still increasing rapidly, but little known about the prevalence and characteristics fatal cases in children Indonesia. This study aimed to describe with COVID-19 outcomes a tertiary referral hospital Indonesia.MethodsThis cross-sectional used data collected from medical records patients admitted Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia March October 2020.ResultsDuring period, 490 were diagnosed suspected probable...
Background: Indonesia has a high number of COVID-19 cases and mortalities relative to not only among the Asia Pacific region but world. Children were thought be less affected by virus compared adults. Most public data reported combined between adults children. The Indonesian Pediatric Society (IPS) was involved in response, especially area child health. One IPS's activities is collecting registries from each their chapters provide better understanding Objective: objective this study share...
Background Copy Number Alterations (CNAs) are changes in DNA structure that lead to gain or loss of copies sections the genome. They correlate with unfavorable prognostic outcomes pediatric leukemia, influencing treatment resistance, relapse rates, and overall survival. Identifying high-risk patients a likelihood CNA positivity is essential for understanding its association clinical characteristics laboratory findings. Since routine testing costly, recognizing simple markers predict presence...
This study compares the minimally invasive Bilistick and a noninvasive method with standard Total Serum Bilirubin (TSB) measurement in preterm newborns receiving phototherapy. We assess agreement of Transcutaneous Bilirubinometer (TcB) bilirubin measurements TSB infants was measured by using TcB 94 RSCM Jakarta Neonatal Ward from October 2016 to March 2017, gestational ages < 35 weeks, before phototherapy after 24 48 h There significant correlation before, at between either (r = 0.874; r...
Post-operative systemic inflammation response syndrome (SIRS) is an event that results from surgical trauma, white blood cells contact activation, and intra-surgical bacterial translocation, which difficult to distinguish sepsis. Presepsin a novel biomarker increased since the early stages of infection can be used confirm diagnosis post-operative infectious complications. This study aimed investigate diagnostic performance presepsin for complications compared other well-known biomarkers.This...
All sectors are affected due to COVID-19 pandemic occurring worldwide, including the education industry. School closure had been taking place for more than a year in Indonesia. Despite controversies, Indonesian government decided begin school reopening.This study aims assess parental readiness reopening, and factors affecting attitude toward reopening.A cross-sectional using online questionnaire distributed via official Pediatric Society (IPS) social media account collected between March...
Latar belakang. Leukemia mieloblastik akut (LMA) merupakan penyakit keganasan yang sering ditemukan pada anak. Hasil pengobatan LMA di Departemen Ilmu Kesehatan Anak RSCM dalam satu dekade terakhir belum pernah dievaluasi. Tujuan. Mengetahui karakteristik pasien dan evaluasi hasil serta protokol pengobatan.Metode. Penelitian deskritif dilakukan secara retrospektif terhadap rekam medis didiagnosis antara Januari 2007-Desember 2010 RSCM. Karakteristik klinis laboratoris dicatat, dianalisis....
Infeksi yang terkait dengan neutropenia pasca kemoterapi merupakan salah satu penyebab morbiditas danmortalitas cukup sering pada pasien kanker. Neutropenia selain akan memperpanjanglama rawat dan meningkatkan risiko infeksi, juga menyebabkan tertundanya pemberian danpengurangan dosis kemoterapi. Hal ini secara tidak langsung mempengaruhi kesintasan pasien.Hematopoietic growth-stimulating factor adalah sitokin mengatur proliferasi, diferensiasidan fungsi sel hematopoietik. Penggunaan...
Background Menarcheal age is important in adolescent girls due to its associations with health outcomes at adulthood. Modifiable factors that may influence menarcheal include body fat mass and distribution.
 Objective: To investigate possible correlations between distribution menarche girls.
 Methods This study was a cross-sectional on 32 aged 10-15 years Central Jakarta, who experienced within the time period of July September 2019. Data collected by recall. Body were calculated...
Background Children with cerebral palsy (CP) often have feeding difficulties due to their disability. This results in inadequate calorie intake which finally leads malnutrition. Several studies found that 30-90% of children CP associ- ated There has been no sufficient published data about this problem Indonesia. Objective To determine the prevalence and malnutrition CP. Methods A cross-sectional study was done from January September 2005 pediatric outpatient clinic Dr. Cipto Mangunkusumo...
Functional gastrointestinal disease (FGID) has a worldwide prevalence of 10-45%, and is one the most common causes recurrent abdominal pain in children. FGID characterized with discomfort changes bowel movement. Alteration gut microbiota associated FGID, but data are limited, there no from Indonesia.A case-control study was conducted 22 children 28 healthy subjects aged 13-18 years at junior high school senior Central Jakarta. diagnosed using Rome IV criteria. Age, sex, level education were...
Background Breast milk has bioactive substances that modulate gastrointestinal maturation and maintain mucosal integrity of the gut in infants. Markers are both non-invasive reliable, such as fecal alpha-1 antitrypsin (AAT), calprotectin, secretory immunoglobulin A (sIgA) have been used to assess adults. Higher AAT levels may imply greater enteric protein loss due increase intestinal permeability immaturity gut.Objective To compare exclusively breastfed (BF) formula fed (FF) infants aged 4-6...
Backgi-ound Surgery has been the standard therapy for secundumatrial septa! defect (ASD) closure, but it significant associatedmorbidities related to st ernotomy, car diopulmonary bypass,complications, residual scars, and trauma. A less invasive nonsurgicalapproach with transcatheter devices was developed toocclude ASD. Amplatzer® occluder (ASO) is a commondevice in closure.Objective To compare two secundum ASD closure procedures,transcatheter by ASO surgical terms ofefficacy, complications,...
Latar belakang. Peningkatan angka kelangsungan hidup pasien thalassemia menyebabkan terdeteksinya berbagai penyakit komorbid termasuk komplikasi pada ginjal. Anemia kronis, kelebihan besi, dan pemakaian kelasi terutama besi oral diduga berpengaruh fungsi Berbagai derajat disfungsi tubular abnormalitas laju filtrasi glomerulus (LFG) dideteksi dengan macam pemeriksaan. Tujuan. Membandingkan ginjal (tubulus glomerulus) yang mendapatkan oral.Metode. Penelitian potong lintang ini dilakukan di...
Introduction: During the COVID-19 pandemic, social media has become main platform to find information in every aspect. It is important for professional organizations develop their field. The Indonesian Pediatric Society (IPS) distributed through various channels, like Professional Official Website. formed reach target users, hoping that will be spread evenly among all parents. This study aims describe how IPS ecosystem provides trusted health information, which can help disseminate parents...
Acute Lymphoblastic Leukemia (ALL) is the most common malignancy occurring in children. Copy number alterations (CNA) like PAX5, CDKN2A/2B, PAR1 Region, ETV6, IKZF1, BTG1, and RB1 gene deletion are important genetic events that define prognosticate B-cell ALL. Thus, this study aimed to evaluate associations of CNA with induction phase remission status childhood
Abstract Background Pharmacokinetic (PK) studies of low‐dose prophylaxis (LDP) coagulation factor VIII (FVIII) in children with severe haemophilia A (SHA) are scarce. Objective This study aims to investigate the PK profile SHA receiving LDP FVIII. Methods Paediatric patients FVIII infusions (10 IU/kg twice weekly) were included. profiles estimated using Web Accessible Population Service for Haemophilia (WAPPS‐Haemo). The primary outcomes terminal half‐life (t 1/2 ), concentration–time...
Latar belakang. Doksorubisin merupakan obat golongan antrasiklin yang penting dan efektif pada pengobatan tumor padat anak. mencegah sintesis RNA DNA melalui proses interkalasi. Kardiotoksisitas dilaporkan paling banyak karena penggunaan doksorubisin tersebut sehingga penggunaannya masih terbatas.Tujuan. Mengetahui fungsi jantung anak dengan osteosarkoma setelah mendapat terapi di RSCM.Metode. Studi deskriptif potong lintang dilakukan RSCM, Divisi Hematologi-Onkologi IKA Sub Bagian Onkologi...
Latar belakang. Leukemia mieloblastik akut cenderung memiliki risiko terkena infeksi yang lebih tinggi dibandingkan keganasan lainnya. Angka kematian pada pasien LMA di Departemen Ilmu Kesehatan Anak FKUI/RSCM cukup tinggi, dan sebagian besar disebabkan oleh atau sepsis.Tujuan. Mengetahui gambaran terjadi FKUI/RSCM.Metode. Penelitian deskritifretrospektif dilakukan terhadap rekam medis anak penderita terdiagnosis antara Januari 2007-Desember 2010. Hanya data biakan darah urin diikutsertakan...
Background Over the years, survival rate of children with osteosarcoma has increased improved management. However, tends to be lower in low-middle-income countries.
 Objective To report a single center Indonesia and evaluate outcomes treatment modalities currently used.
 Methods We performed retrospective analysis medical records pediatric patients Cipto Mangunkusumo Hospital from 2015 2019. Patients were categorized based on age group, sex, primary tumor location, modalities,...
Malignancy is a significant public health problem, both globally and in Indonesia. Chemotherapy one of the modality malignancy cases. Carboplatin (cis-diammine-cyclobutanedi-carboxylato platinum) second-generation platinum compound that has often been used management cases malignancies. On other hand, side effects cytotoxic drugs need to be considered, especially ototoxic effects. Ototoxicity dysfunction damage structure inner ear caused by or certain chemicals. The aim this study assess due...
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by abnormal clonal proliferation of dendritic cells. The incidence LCH 1 to 3 cases per million children worldwide, and occurs most frequently in 1–4 years age. etiopathogenesis LCH, whether it neoplastic or reactive, still controversial. has wide spectrum clinical features, dermatological abnormalities usually occur early. frequent lesions are elevated yellowish-red translucent papules about 1–2 mm diameter generally...
Latar belakang. Penderita leukemia limfoblastik akut (LLA) akan mengalami perubahan status oksidan dan antioksidan sejak awal diagnosis selama kemoterapi. Vitamin E merupakan antikarsinogenik berperan mencegah kerusakan oksidatif pada struktur sel jaringan lewat reaksi pemecahan radikal bebas. Tujuan. Mengetahui pengaruh vitamin terhadap kadar oksidan, enzim transaminase, insiden demam neutropenia LLA saat selesai kemoterapi fase induksi. Metode. Uji klinis acak tersamar ganda yang...