- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Neonatal and Maternal Infections
- Public Health and Nutrition
- Breastfeeding Practices and Influences
- Sepsis Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Child Nutrition and Water Access
- Retinopathy of Prematurity Studies
- Methemoglobinemia and Tumor Lysis Syndrome
- Pediatric Hepatobiliary Diseases and Treatments
- Global Maternal and Child Health
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Heme Oxygenase-1 and Carbon Monoxide
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Hemoglobinopathies and Related Disorders
- Methodologies in Health Research and Practice
- Streptococcal Infections and Treatments
- Healthcare Quality and Satisfaction
- Hemodynamic Monitoring and Therapy
- Gut microbiota and health
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2016-2025
University of Indonesia
2016-2025
Gatot Soebroto Army Hospital
2015
The neonatal mortality rate in Papua Province of Indonesia is unacceptably high. To address the issue, Ministry Health and UNICEF initiated a hospital mentoring programme from 2014 to 2016 improve quality care health workers' capacity provide care. This study aimed assess impact on mortality. was conducted at Biak District Hospital, Indonesia. compared for three periods: preintervention (2011-2013), mentorship intervention phase (2014-2016) postintervention (2017-2020). combination...
The successful promotion of facility births in low and middle-income countries has not always resulted improved neonatal outcome. We evaluated key signal functions pertinent to Level II care determine readiness for high risk/ small sick newborns.Facility babies was determined through self-evaluation using a pre-designed checklist selected referral hospitals Uganda (10), Indonesia (4) India (2) with focus on the Sub-Saharan country greater challenges.Most facilities reported having continuous...
Early diagnosis and prompt antibiotic treatment are crucial to reducing morbidity mortality of early-onset sepsis (EOS) in neonates. However, this strategy remains challenging due non-specific clinical findings limited facilities. Inappropriate antibiotics use is associated with ineffective therapy adverse outcomes. This study aims determine the characteristics EOS neonatal-intensive care units (NICUs) Indonesia, informing efforts drive improvements prevention, diagnosis, EOS.A descriptive...
Neonatal mortality is one of the key impediments in achieving global sustainable development goals, especially lower middle income countries (LMICs). As an LMIC with highest reported neonatal rate Southeast Asia, Indonesia faces inequitable distribution health facilities across archipelago. Therefore, this paper, we aim to evaluate determinants search for better strategies overcome problem.We conducted analysis 2017 Demographic Health Survey dataset 10,838 live-born infants born from...
Latar belakang. Air susu ibu merupakan nutrisi ideal untuk bayi. World Health Organization (WHO) menganjurkan pemberian ASI eksklusif hingga 6 bulan. Data Survey Demografi dan Kesehatan Indonesia (SDKI) tahun 2003 2007 menunjukkan angka di cenderung turun. Beberapa penelitian terdapat beberapa faktor yang memengaruhi eksklusif.Tujuan. Mengetahui proposi pada bayi dilakukan IMD, mengetahui faktor-faktor memengaruhinya.Metode. Penelitian potong lintang analitik dengan pengumpulan data melalui...
Purpose: Feeding tolerance is extremely important in preterm infants.This study aimed to evaluate whether infants receiving Lactobacillus reuteri DSM 17938 would develop fewer symptoms of feeding intolerance.Secondary outcomes were duration parenteral nutrition, time reach full feeding, length hospital stay, sepsis, necrotizing enterocolitis (NEC), diarrhea, and mortality.Methods: This double-blind randomized controlled trial L. versus placebo included 94 neonates with a gestational age...
Background Optimum neonatal resuscitation practices are vital for improving survival and neurodevelopment outcomes, particularly in extremely preterm infants. However, such may vary between high-income countries (HICs) low-middle-income (LMICs). This study aimed to evaluate the of high-risk infants a large multi-country sample healthcare facilities among HICs LMICs Asia under AsianNeo Network. Methods In 2021, customized 6-item online survey on born at <29 weeks gestation (or birth...
In vitro fertilisation (IVF) offers a solution for infertility but poses increased obstetrical and perinatal risks, including higher rates of preterm birth, low birth weight congenital anomalies. Particularly, IVF-related multiple pregnancies face significantly risks prolonged hospital stays. This study compares neonatal outcomes between IVF natural conception, as well singleton over the past decade. retrospective reviewed medical records babies born at Cipto Mangunkusumo Kencana Hospital...
Preterm birth and very low weight (VLBW) remain major contributors to neonatal morbidity mortality, particularly in low-income settings such as Indonesia, where healthcare resources are limited. In response, the Ministry of Health introduced mentoring programs 2014, followed by intensive training initiatives 2015. These interventions substantially improved survival rates for LBW infants however, they face significant growth developmental challenges. This study aims investigate development...
Introduction Prematurity is the most common cause of neonatal mortality and morbidity. Most preterm infants receive multiple packed red cell (PRC) transfusions during hospitalization. Meanwhile, PRC can increase iron levels. However, to date, there no consensus regarding supplementation in who have received transfusions. The objective this study determine status premature aged 28-32 weeks make recommendations supplementation. Methods This a prospective cohort 70 born at Cipto Mangunkusumo...
Background Preterm infants are at high risk of developing sepsis. An imbalance between the normal gut and pathogenic microbiomes, known as dysbiosis, has been proposed a condition that leads to neonatal Objective To assess for an association dysbiosis Methods A prospective cohort study was conducted involving very preterm or low birth weight admitted Neonatal Unit, Cipto Mangunkusumo Hospital, Jakarta, from November 2019 January 2021. The primary outcome proven and/or clinical independent...
This study compares the minimally invasive Bilistick and a noninvasive method with standard Total Serum Bilirubin (TSB) measurement in preterm newborns receiving phototherapy. We assess agreement of Transcutaneous Bilirubinometer (TcB) bilirubin measurements TSB infants was measured by using TcB 94 RSCM Jakarta Neonatal Ward from October 2016 to March 2017, gestational ages < 35 weeks, before phototherapy after 24 48 h There significant correlation before, at between either (r = 0.874; r...
The real prevalence and clinical burden of severe neonatal jaundice are undefined due to difficulties in measuring total serum bilirubin (TSB) outside secondary tertiary centers. To assess the diagnostic performance point-of care Bilistick System (BS) identifying patients requiring treatment. Between April 2015 November 2016, 1911 neonates, were recruited participate study. Blood samples simultaneously collected for TSB determination by BS hospital laboratory (Lab). Data sent Bilimetrix...
Background: Single nucleotide polymorphism (SNP) variants of the uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) gene have been studied as an important factor in neonatal hyperbilirubinemia (jaundice) severity. Specific ethnicities, including Asians, certain SNPs that appear more frequently than others. Aim: To identify most common Indonesian neonates and their association with severity hyperbilirubinemia. Methods: Eighty-eight inborn outborn jaundiced infants from three different...
Stunting, atau perawakan pendek, berhubungan erat dengan hambatankemampuan kognitif dan kualitas hidup. Prevalensi stunting di Indonesiamencapai 30,8% tahun 2018. Stunting dipengaruhi pemenuhan nutrisi diawal kehidupan, salah satunya melalui ASI eksklusif. Meskipun cakupan ASIeksklusif Indonesia sudah 74,5%, hubungan eksklusifseringkali tidak konsisten akibat keberagaman kuantitas ASI.Penelitian ini ingin mengetahui efek eksklusif terhadap diKabupaten Bogor, sebagai satu daerah tinggi...
Background Postnatal growth failure (PGF) frequently occurred among preterm infants with malnutrition. The decline in a weight-for-age z -score of ≥1.2 has been proposed to define PGF. It was unknown whether this indicator would be useful Indonesian infants. Methods Infants &lt;37 weeks gestational age born between 2020 and 2021, both stable unstable, were recruited for prospective cohort study during hospitalization the level III neonatal intensive care unit at Cipto Mangunkusumo...
Aims The aim of the study was to evaluate significance total bilirubin, aspartate transaminase ( AST ), alanine and gamma‐glutamyltransferase GGT ) for predicting outcome in sepsis‐associated cholestasis. Methods A retrospective cohort review hospital records performed 181 neonates admitted N eonatal C are U nit. comparison between subjects with low high liver values based on cut‐off from ROC analysis. We defined poor prognosis be when a subject had prolonged cholestasis more than 3.5...
Acinetobacter baumannii ( A. ) is Gram-negative coccobacilli that has emerged as a nosocomial pathogen. Several reports in Indonesia showed the continuous presence of . This study aimed to determine incidence bacteremia neonates Neonatal Unit Dr. Cipto Mangunkusumo Hospital (RSCM), Jakarta, Indonesia, and assess its role blood stream infection using antibiogram genotyping by pulsed-field gel electrophoresis (PFGE). Subjects were with clinical sepsis. Blood specimens from samples suspected...
The genetic involvement in unconjugated neonatal hyperbilirubinemia has been extensively studied. Despite the high incidence of Indonesia, studies are lacking. objective this study is to elucidate role polymorphism UGT1A1 Neonatal Hyperbilirubinemia Bengkulu, Indonesia. There were 41 neonates enrolled study; 30 had a total serum bilirubin level ≥ 15 mg/dL (hyperbilirubinemia neonates) while 11 < (control neonates). Genetic mutations Exon 1, UGT1A1*6 (c211g > a) and one promoter region,...