Neonatal mortality is one of the key impediments in achieving global sustainable development goals, especially lower middle income countries (LMICs). As an LMIC with highest reported neonatal rate Southeast Asia, Indonesia faces inequitable distribution health facilities across archipelago. Therefore, this paper, we aim to evaluate determinants search for better strategies overcome problem.We conducted analysis 2017 Demographic Health Survey dataset 10,838 live-born infants born from...

Purpose: Feeding tolerance is extremely important in preterm infants.This study aimed to evaluate whether infants receiving Lactobacillus reuteri DSM 17938 would develop fewer symptoms of feeding intolerance.Secondary outcomes were duration parenteral nutrition, time reach full feeding, length hospital stay, sepsis, necrotizing enterocolitis (NEC), diarrhea, and mortality.Methods: This double-blind randomized controlled trial L. versus placebo included 94 neonates with a gestational age...

Most preterm infants exhibit atypical and immature feeding skills. Even though have fulfilled the oral readiness criteria, they still do not optimal ability. This study aimed to determine various factors affecting ability in Indonesian who criteria but been able feed orally. A cross-sectional included 120 admitted five tertiary hospitals Jakarta, Indonesia. Participants were born at 28–34 weeks gestational age had as inclusion criteria: (1) stable cardiorespiratory status, (2) achieved full...

BACKGROUND Preterm infants often require continuous positive airway pressure due to immature respiratory tracts. Bronchopulmonary dysplasia (BPD) manifests as prolonged oxygen dependence until 28 days of age and is classified into mild, moderate, or severe forms. The lung recruitment maneuver (LRM) aims reopen collapsed alveoli, enhancing oxygenation during mechanical ventilation using the assist control volume guarantee mode (MV-AC/VG). This study aimed evaluate impact LRM on alveolar...

Background Postnatal growth failure (PGF) frequently occurred among preterm infants with malnutrition. The decline in a weight-for-age z -score of ≥1.2 has been proposed to define PGF. It was unknown whether this indicator would be useful Indonesian infants. Methods Infants <37 weeks gestational age born between 2020 and 2021, both stable unstable, were recruited for prospective cohort study during hospitalization the level III neonatal intensive care unit at Cipto Mangunkusumo...

Indonesia has high numbers of preterm birth, i.e., around 600,000 births annually. It imposes a significant burden on the Indonesia's healthcare system. therefore requires its own evidence-based reference to manage premature neonates and ex-preterm infants who subsequently survived. No long-term study in been conducted, we aim evaluate growth development until pre-pubertal stage.We at Cipto Mangunkusumo General Hospital (CMGH) designed prospective cohort infants, Cohort Indonesian Preterm...

Background Patent ductus arteriosus (PDA) is a congenital heart disease most commonly occurring in premature infants. Spontaneous (DA) closure infants has been suggested to be associated with duct lumen maturity and the DA sensitivity prostaglandin E2 (PGE2).Objective To assess for possible correlation between serum PGE2 levels PDA size infants.Methods This observational study using repeated measurements on detected at days 2-3 of life was undertaken Cipto Mangunkusumo Hospital Fatmawati...

Latar belakang. Deposit Seng (Zn) berperan terhadap fungsi metabolik tubuh. Bayi kurang bulan mempunyai cadangan Zn yang rendah pada masa fetus, kebutuhan tinggi setelah lahir, kapasitas untuk mengabsorbsi dan retensi zat makanan terbatas. Gambaran klinis dari defisiensi berat yaitu dermatitis, iritabel, kandidiasis oral, diare, mineralisasi tulang buruk, gangguan motorik kognitif, meningkatnya risiko terkena infeksi, retardasi pertumbuhan.Tujuan. Untuk menentukan prevalens faktor...

Background Respiratory distress is the most common cause of morbidity in premature babies delivery room. Nasal continuous positive airway pressure (nCPAP) widely used as preferred modality treatment, although it may nasal trauma. Heated, humidified high-flow (HHHFN) cannula an alternative oxygen therapy, yet safety and efficacy has not been studied.
 Objective To compare HHHFN nCPAP with gestational age > 28 to < 35 weeks moderate respiratory distress.
 Methods We conducted a...

Background Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most connnon enzyme in world. Itis a risk factor for hyperbilirubinemia neonates, which can cause serious complications such as bilirubin􀁗induced encephalopathy or kernicterus. WHO recommends universal neonatal screening G6PD when frequency exceeds 3􀁗5% of male newborns.Objective To assess prevalence among neonates Bunda Women and C hildren Hospital (Bunda WCH), Jakarta, order to detennine if there need routine...

Background In vitro fertilization (IVF) shows potential to improve pregnancy success, especially for infertile couples. This technique has some risks neonates in the perinatal period and may affect their future health.
 Objective To investigate characteristics clinical outcomes of from IVF-conceived pregnancies.
 Methods retrospective study was conducted pregnancies January December 2021 at Bunda Women’s Children’s Hospital, Jakarta. We gathered data medical records about maternal...

Background Zinc is one of the micronutrients that found deficient in preterm infants. To date, no parenteral zinc supplements are available Indonesia and there recommendation established for routine supplementation infants.
 Objective evaluate impact on growth indicators morbidity Methods This double-blind, randomized controlled trial included infants aged 28-32 weeks who were assigned to two groups: first group received a 10 mg supplementation, while second (control) placebo. At...

Latar belakang. Remaja merupakan kelompok risiko tinggi untuk mengalami defisiensi besi. Obesitas pada remaja meningkatkan besi akibat perbedaan pola asupan dan inflamasi kronik derajat rendah. Tujuan. Mengetahui status obes usia 15 -17 tahun. Metode. Penelitian potong lintang – 17 tahun di dua SMU Jakarta Pusat bulan September November 2015. Subjek dibagi menjadi 2 berdasarkan indeks massa tubuh (IMT). dinyatakan bila IMT≥P95 non-obes IMT ≥P5 - <P85. Kepada subjek dilakukan penilaian...

Background Respiratory disorders in premature neonates often require respiratory support. Continous transcutaneous monitoring is an available non-invasive option to monitor CO2 pressure, substituting the need for blood gas analysis as gold standard evaluation practice. Most studies have been conducted on very and extremely preterm neonates, but rarely late moderately neonates. Objective To determine precision accuracy of pressure measuring devices compared arterial 32-36 weeks gestational...

Duktus arteriosus paten (DAP) merupakan kelainan yang sering dijumpai pada bayi prematur. Salah satuupaya tata laksana DAP adalah pemberian terapi farmakologis guna memicu penutupan duktus. Sediaanterapi umumnya digunakan indometasin, suatu penghambat siklooksigenase(COX). Namun akhir-akhir ini diperkenalkan sediaan ibuprofen sebagai alternatif farmakologisyang memiliki efektifitas setara. Dilaporkan seorang prematur (usia gestasi 30 minggu) dengan duktusarteriosus berhasil di obati...

Background Patent ductus arteriosus (PDA) is a congenital heart disease most commonly occurring in premature infants. Spontaneous (DA) closure infants has been suggested to be associated with duct lumen maturity and the DA sensitivity prostaglandin E2 (PGE2).Objective To assess for possible correlation between serum PGE2 levels PDA size infants.Methods This observational study using repeated measurements on detected at days 2-3 of life was undertaken Cipto Mangunkusumo Hospital Fatmawati...

Infiltration of leukemic cells into the central nervous system (CNS) is one causes neurological disorders in patients with acute lymphoblastic leukemia (ALL) that worsen prognosis. This retrospective cohort study aimed to review clinical manifestations children CNS leukemia, their survival pattern and role early leukemial. The curve was developed by Kaplan-Meier method, while comparison curves done log-rank test. Among 128 new ALL patients, 23 (18.0%) suffered from 13 (10.2%) 10 (7.8%)...

Background Of preterm infants born before 32 weeks of gestation, 40-70% have atypical and immature feeding skills, which could delay initiation oral feeding. A formal objective measurement non-nutritive sucking may increase the accuracy determining right time to initiate feeding, however, most hospital perinatology care units do not own a suction pressure device objectively measure parameters.
 Objective To compare subjective (NNS) based on pressure, number suctions per burst, between...

Background Non-nutritive sucking (NNS) maturity has been used as one of the markers oral feeding readiness in infants. Prematurity may hinder attainment NNS milestones. Depending on gestational age (GA) at birth, preterm infants display various degrees immaturity, potentially affecting strength, coordination, and efficiency skills required for NNS.
 Objective To identify progression patterns across groups Indonesia by comparing parameters between moderate-to-late very infants.
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Abstrak Sebagian besar wanita hamil mengalami kolonisasi Streptococcus haemolyticus grup B (SGB) di saluran urogenital yang mempengaruhi kesehatan ibu dan bayi. Deteksi SGB intrapartum perlu pemeriksaan cepat sensitif. Pemeriksaan mikrobiologi untuk mendeteksi menggunakan metode kultur real time polymerase chain reaction (RT-PCR) telah digunakan mendukung diagnosis, namun penggunaannya skrining pada belum pernah diuji keakuratannya Indonesia. Penelitian ini bertujuan mencari terbaik...

Background Lung recruitment maneuvers (LRMs) are a strategy to gradually increase mean positive airway pressure (MAP) expand the alveoli, leading decreased pulmonary vascular resistance and increased cardiac output (CO). However, hemodynamic impact of LRM using assist control volume guarantee (AC-VG) ventilator mode done in preterm infants born at 24 32 weeks’ gestation, especially first 72 hours life, remains unknown.
 Objective To determine effect on right- left ventricular (RVO LVO),...

<p class="abstract"><strong>Background:</strong> Hearing loss is the most common disorder in neonates; it can be best managed if diagnosed at early stage of life. The global prevalence permanent neonatal hearing mainly occurs developing countries, which accounts 0.5 to 5.0 per 1000 live births. objective this study was determine aminoglycoside therapy and other risk factors that induce neonates admitted NICU Cipto-Mangunkusumo General Hospital (CMGH).</p><p...