- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Neurological disorders and treatments
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiomyopathy and Myosin Studies
- Coronary Interventions and Diagnostics
- Virology and Viral Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Chronic Kidney Disease and Diabetes
- Abdominal vascular conditions and treatments
- Inflammatory mediators and NSAID effects
- Adipose Tissue and Metabolism
- MicroRNA in disease regulation
- Vascular Malformations Diagnosis and Treatment
- Coronary Artery Anomalies
- Adipokines, Inflammation, and Metabolic Diseases
- Gout, Hyperuricemia, Uric Acid
- Acute Myocardial Infarction Research
- Computational Drug Discovery Methods
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Parathyroid Disorders and Treatments
General Hospital of Shenyang Military Region
2015-2025
Command Hospital
2024
Tongji University
2022
Shanghai Tenth People's Hospital
2022
Fuzhou General Hospital of Nanjing Military Command
2015
Northern Hospital
2013
Second Hospital of Tianjin Medical University
2010
Tianjin Medical University
2010
Lanzhou University
2010
First Hospital of Lanzhou University
2010
Focal atrial tachycardias (ATs) surrounding the anterior septum (AAS) have been successfully ablated from right (RAS), aortic cusps, and mitral junction. However, strategy for mapping ablation of AAS-ATs has not well defined.Of 227 consecutive patients with AT, 47 (20.7%; mean age, 56.3±11.6 years) were studied; among them, initial was successful at RAS in only 5 14 noncoronary cusp (NCC) 28 33 patients. In 45 patients, 46 48 eliminated 8 NCC 35 (earliest activation time later than that by...
ABSTRACT Background The evidence in the primary prevention of sudden cardiac death (SCD) by using implantable cardioverter defibrillators (ICD) patients with ischemic cardiomyopathy (ICM) is well‐established but remains controversial for those nonischemic (NICM). This study evaluates whether prognostic differences exist between ICM and NICM after ICD implantation. Methods Patients initially undergoing implantation as SCD were retrospectively enrolled from January 2017 to May 2023. Malignant...
Differentiation of preadipocytes into functional adipocytes could be a major target for repressing obesity-induced insulin resistance (IR). However, the molecular mechanisms involved in adipogenesis and development IR are unclear. We report, first time, that miR-574-5p, novel miRNA, promotes to suppress IR. An increase level miR-574-5p significantly induced differentiation mature adipocytes. Conversely, reduction levels blocked vitro. In dual-luciferase reporter assay, it was shown homeobox...
Electrophysiological mapping (EPM) in coronary sinus (CS) branches is feasible for guiding LV lead placement to the optimal, latest activated site at cardiac resynchronization therapy (CRT) procedures. However, whether this procedure optimizes response CRT has not been demonstrated. This study was evaluate effects of targeting guided by EPM during CRT.Seventy-six consecutive patients with advanced heart failure who were referred divided into (MG) and control groups (CG). In MG, lead, also...
Objectives To compare the haemodynamic results and long-term clinical outcomes of intracardiac electrography (QuickOpt®; St Jude Medical, Paul, MN, USA) echocardiography for optimization atrioventricular (AV) interventricular (VV) delays in cardiac resynchronization therapy (CRT). Methods Patients with CRT devices were prospectively enrolled; AV/VV optimized by either QuickOpt® or echocardiography. group underwent both optimization, used to program CRT. All patients followed-up 12 months....
Background Long-term efficacy and safety of tacrolimus-eluting stent (Janus) for treatment coronary artery disease in percutaneous interventions (PCI) "real world" is uncertain. The aim this study was to evaluate the Janus treating heart PCI daily practice, 4-month clopidogrel therapy after implantation feasibility patients with acute myocardial infarction (AMI) first time. Methods From February 20, 2006 August 26, 2006, a total 200 were enrolled randomly assigned receive either (n=100) or...
To establish a simple criterion for determining failed His-bundle pacing (HBP). This states that if stimulus to QRS end interval is longer than potential ('S-QRSend > H-QRSend') then HBP can be determined.We performed retrospective analysis on 737 tests around in 241 patients and prospective 400 123 patients. A successful defined as whole captured with or without capture of adjacent ventricular myocardium, otherwise, was considered. The output criteria effective refractory period were used...
Conventional right ventricular pacing combined with coronary venous (CVP) is a mainstay for cardiac resynchronization therapy (CRT). However, QRS duration of conventional CRT may be frequently more than 130 ms. This study aimed to evaluate the effectiveness narrowing by bilateral septal (BSP) in combination CVP (BSP-CRT).Fourteen patients > ms after failure physiological conduction system were enrolled. Electrophysiologic characteristics compared among different modes during procedure. BSP...
A non-responder heart failure patient to conventional cardiac resynchronization therapy (CRT) received novel mid-septal pacing (MSP) optimized CRT (MOT-CRT) by at middle part of septum which captured both right and left ventricular in combination with coronary venous (CVP). The QRS duration was shortened from 142 ms the 110 improved function. MSP bypassed slow transseptal conduction reduced 31 activation delay compared septal pacing. This case demonstrates for first time that MOT-CRT might...
Objective To investigate the feasibility and short-term outcomes in clinical application of His bundle pacing (HBP) as first-choice treatment for patients with heart failure (HF) His-Purkinje conduction disease (HPCD) . Methods The cardiac resynchronization therapy (CRT) indications HPCD from March 2016 to December 2017 General Hospital Shenyang Military Region were enrolled this study. All agreed that HBP serves correction. The success rate correction, parameter, performance effect...
<h3>Objectives</h3> More and more active-fixation leads were used in the right atrium during implantation of pacemaker, aim this study was to explore feasibility atrial application pacemaker observe changes long-term pacing parameters. <h3>Methods</h3> Sixty patients (32 males 28 females, mean aged 65.25 ± 13.95 years) involved study, 4 cases implanted with single-chamber (AAIR) 56 dual-chamber (DDDR), who underwent for permanent pacing. The follow-up period 12 months after implantation....
<h3>Background</h3> More and more active-fixation leads were used in the implantation of pacemaker, but compared with traditional passive-fixation leads, differences pacing parameter not clearly known. <h3>Objective</h3> The aim this study was to compare parameters right ventricular apical pacing. <h3>Methods</h3> There 54 patients implanted single or dual chamber pacemaker involved from January 2010 May followed up for 3 months after operation. In these 21 lead (Group I) 33 II). All...
Introduction:The detrimental effects of right ventricular apical pacing on left function has driven interest in selective site pacing, predominantly the mid-sepal pacing.There is currently no information long-term lead electrical performance from this site.To investigate feasibility and safety patients with active fixation compared to passive apex.Methods: All who underwent successful implantation permanent pacemakers between January 2005 April 2008 were retrospectively analyzed, included...
Background. Heart failure (HF) is the terminal stage of all cardiovascular events. Although implantable cardioverter defibrillator (ICD) therapies have reduced mortality among high-risk HF population, it necessary to determine whether certain factors can predict even after cardiac device implantation. Growth stimulation expressed gene 2 (ST2) an emerging biomarker for patient stratification in different clinical settings. Aims. This study aimed investigate relationship between baseline...
Objective To evaluate the potential association of serum sclerostin with development coronary artery calcifications(CAC)in maintenance hemodialysis (MHD) patients. Methods Ninety-two patients who were on MHD between Jan 2014 and 2015 in dialysis center enrolled prospectively. Serum was tested. CAC measured by multi-slice computed tomography (MSCT) scanning, score (CACs) calculated. Logistic regression analysis used to determine risk factor The diagnostic value for assessed using...