A5056497109- Dementia and Cognitive Impairment Research
- Frailty in Older Adults
- HIV Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- Action Observation and Synchronization
- Aging and Gerontology Research
- Cognitive Science and Mapping
- Hearing Impairment and Communication
- Axon Guidance and Neuronal Signaling
- Functional Brain Connectivity Studies
- Memory and Neural Mechanisms
- Educational and Social Studies
- Blood Pressure and Hypertension Studies
- Intensive Care Unit Cognitive Disorders
- Microtubule and mitosis dynamics
- Legal and Labor Studies
- Memory Processes and Influences
- Infectious Encephalopathies and Encephalitis
- Cellular Mechanics and Interactions
- Cerebral Palsy and Movement Disorders
- Context-Aware Activity Recognition Systems
University Hospital of Lausanne
2008-2025
University of Lausanne
2001-2023
University of Exeter
2021
necessary to design long-lasting effective treatments for neurorehabilitation: (i) motor-cognitive training, (ii) evidence-based neuroscience principles, in particular those related body perception, (iii) motivational games, and (iv) empowerment techniques. Then, we propose virtual reality (VR) as the appropriate medium encompass all requirements mentioned above. VR is arguably one of most suitable technologies neurorehabilitation able integrate techniques principles into motivating training...
Abstract Cognitive complaints in the absence of objective cognitive impairment, observed patients with subjective decline (SCD), are common old age. The first step to postpone is use techniques known improve cognition, i.e., enhancement techniques. We aimed provide clinical recommendations performance cognitively unimpaired individuals, by using cognitive, mental, or physical training (CMPT), non-invasive brain stimulations (NIBS), drugs, nutrients. made a systematic review CMPT studies...
Dementia diseases represent a major burden for the directly affected people, their relatives and modern society. Despite considerable efforts in recent years, early accurate disease diagnosis monitoring is still challenge while no cure available most cases. New drugs, particular disease-modifying therapies, technological advancements offer promising perspectives. The integration of novel biomarkers, artificial intelligence digital health tools has potential to transform dementia care, making...
Abstract Multidomain interventions have shown tremendous potential for improving cognition in older adults. It is unclear if multidomain can be delivered remotely and whether remote intervention beneficial adults who are vulnerable or at risk of cognitive decline. In a 26-week multi-site, home-based, double-blind, randomized controlled trial, 120 cognitively healthy (75 robust, 45 pre-frail; age range = 60–94) recruited from Switzerland, Canada, Belgium were to receive either the...
Abstract People with HIV may report neurocognitive complaints, or without associated impairment, varying between individuals and populations. While the genome could play a major role, large systematic viral genome-wide screens to date are lacking. The Swiss Cohort Study biannually enquires complaints. We quantified broad-sense heritability estimates using partial ‘pol’ sequences from resistance database performed near full-length association study for longitudinal area under curve of all...
Abstract Background In older adults, multidomain training that includes physical and cognitive activities has been associated with improvement of health. The goal the multisite StayFitLonger study is to assess a home-based computerised programme, which combines exercises, stimulating virtual coaching. Methods One hundred twenty-eight cognitively healthy adults will be recruited from community in Switzerland, Canada Belgium. comprise (1) 26-week double-blind randomized controlled efficacy...
We previously showed that anticholinergic (ACH) medications contribute to self-reported neurocognitive impairment (NCI) in elderly people with human immunodeficiency virus (PWH). The current cross-sectional study further evaluated the effect of ACH and sedative drugs on function PWH who underwent comprehensive neuropsychological evaluation. A medication review was performed enrolled prospective Neurocognitive Assessment Metabolic Aging Cohort within Swiss HIV Study. functions were analyzed 5...
With ageing, comorbidities such as neurocognitive impairment increase among people living with HIV (PLWH). However, addressing its multifactorial nature is time-consuming and logistically demanding. We developed a neuro-HIV clinic able to assess these complaints in 8 h using multidisciplinary approach.People were referred from outpatient clinics Lausanne University Hospital. Over participants underwent formal infectious disease, neurological, neuropsychological psychiatric evaluations,...
The possibility of flexibly retrieving our memories using a first-person or third-person perspective (1PP 3PP) has been extensively investigated in episodic memory research. Here, we used Virtual Reality-based paradigm to manipulate the visual during encoding stage investigate age-related differences formation experienced from 1PP vs. 3PP. 32 young adults and seniors participated study. Participants navigated through two virtual cities encode complex real-life events, either (as if their...
A "Long COVID" care management was created at the Leenaards Memory Centre (Lausanne University Hospital) to meet high demand for neuropsychological examinations in patients which have persistent symptoms several months. multidisciplinary evaluation specifically addressing aspects of fatigue and sleep as well cognition has been developed receive these patients. Depending on severity their symptoms, they are then oriented towards a holistic group treatment, integrating cognitive remediation...
Current recommendations for the management of neurocognitive complaints in people living with HIV (PLWH) include a series evaluations that may start exclusion depression followed by stepwise approach comprised neurological, neuropsychological and psychiatric assessment, alongside performance an MRI lumbar puncture. This extensive evaluation is time demanding, face PLHW multiple medical consultations waiting lists. As response to these challenges, we have developed one-day Neuro-HIV platform...
Over the last fifty years, technological revolution — also called “digital revolution” —has been continuously reshaping our daily lives and bringing about new opportunities challenges. This paper examines practice of “teleneuropsychology” that has resulted from this revolution, raising three specific points: 1) the digitization existing assessment tools enables neuropsychologists to more accurately record their patients’ behavior simplifies data storage; 2) teleconsultations have seen...