A5025217572- Advanced Photocatalysis Techniques
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Anesthesia and Neurotoxicity Research
- Gas Sensing Nanomaterials and Sensors
- Supercapacitor Materials and Fabrication
- MXene and MAX Phase Materials
- Advanced biosensing and bioanalysis techniques
- Copper-based nanomaterials and applications
- Corrosion Behavior and Inhibition
- Hydrogen embrittlement and corrosion behaviors in metals
- Extracellular vesicles in disease
- Advancements in Battery Materials
- Machine Fault Diagnosis Techniques
- Fish biology, ecology, and behavior
- Intensive Care Unit Cognitive Disorders
- 2D Materials and Applications
- Circular RNAs in diseases
- Catalytic Processes in Materials Science
- Polymer Surface Interaction Studies
- Fuel Cells and Related Materials
- Paleontology and Evolutionary Biology
- TiO2 Photocatalysis and Solar Cells
- Antimicrobial Peptides and Activities
- Polydiacetylene-based materials and applications
Zhongda Hospital Southeast University
2023-2025
State Key Laboratory of Digital Medical Engineering
2023-2025
Tianjin Medical University General Hospital
2020-2025
National University of Defense Technology
2024
Jiujiang Vocational University
2024
Xi'an Honghui Hospital
2019-2024
Xi'an Jiaotong University
2019-2024
Harbin Institute of Technology
2021-2024
Southwest Petroleum University
2024
Beijing Normal University
2024
DNA origami nanostructures are versatile substrates for the single‐molecule investigation of biomolecular interactions as they enable display molecular species in complex arrangements. Herein, fundamental limitations this approach explored by displaying pairs small‐molecule ligands protein trypsin on and adjusting their ligand–ligand spacing with subnanometer precision. Bidentate binding to ligand is investigated atomic force microscopy (AFM), microscale thermophoresis (MST), dynamics...
Although accumulating evidence indicated that modulating macrophage polarization could ameliorate the immune microenvironment and facilitate repair of spinal cord injury (SCI), underlying mechanism phenotypic switch is still poorly understood. Exosomes (Exos), a potential tool cell-to-cell communication, may play important roles in cell reprogramming. Herein, we investigated macrophages-derived exosomes played for SCI microenvironment. In this study, found fraction M2 macrophages was...
Exceptionally preserved carbonate reticulated ridge structures are documented from the lower Middle Triassic Guanling Formation of Luoping area, eastern Yunnan Province, southwestern China. Macrostructures suggest these morphologically similar to growth-related in ancient and modern microbial mats. Other such features as minute load pyrite crystals beneath layers on bedding surfaces overlain by a black carbonaceous shale layer. Clay minerals oriented parallel at top, they usually form wavy...
Abstract Small extracellular vesicles (sEVs) act as a critical mediator in intercellular communication. Compared to sEVs derived from vitro sources, tissue‐derived can reflect the vivo signals released specific tissues more accurately. Currently, studies on role of cochlea have relied studying sources. This study evaluates three cochlear tissue digestion and sEV (CDsEV) isolation methods, first proposes that optimal approach for isolating CDsEVs using collagenase D DNase І combined with...
Although biomaterials strategies have been regarded as a promising approach for the treatment of osteoarthritis (OA), identifying novel drugs to be delivered modulate macrophage polarization is still unclear. As commonly used non-steroidal anti-inflammatory drug OA, Imrecoxib may direct and sustain phenotype. However, specific protective mechanism in OA remains This study aims investigate whether would treat by regulating synovial polarization. The research involves constructing mouse...
Abstract Cisplatin‐induced ototoxicity remains a clinical dilemma with limited mechanistic understanding and no food drug administration (FDA)‐approved therapies. Despite emerging roles of small extracellular vesicles (sEV) in ototoxicity, their molecular cargo profiles causal to cisplatin‐induced are unexplored. This study systematically investigates sEV derived from cochlear explants treated cisplatin (Cis‐sEV) controls (Ctrl‐sEV) using multi‐omics profiling. Through RNA sequencing, 83...
Bacterial colonization of abiotic surfaces such as those medical implants, membrane filters, and everyday household items is a process tremendous importance for public health. Bacteria use adhesive cell surface structures called adhesins to establish contact with surfaces. Among them, protein filaments type IV pili are particularly important found in many Gram-negative pathogens Pseudomonas aeruginosa. Understanding the interaction adhesin proteins different at molecular level thus...
Introduction: Perioperative neurocognitive disorder (PND) has attracted consistently increasing attention worldwide. However, there are few bibliometric studies that systematically evaluate this field. This study aimed to visualize the knowledge structure and research trends in PND through bibliometrics help understand future development of basic clinical research. Methods: Literature related Web Science PubMed from 1990 2022 were collected keywords retrospectively. Additionally, source...