A5101476008- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Environmental Toxicology and Ecotoxicology
- Calcium Carbonate Crystallization and Inhibition
- Bone Tissue Engineering Materials
- Advanced biosensing and bioanalysis techniques
- Porphyrin and Phthalocyanine Chemistry
- Pharmacological Effects and Assays
- Photodynamic Therapy Research Studies
- Advanced Nanomaterials in Catalysis
- Insect and Pesticide Research
- Autophagy in Disease and Therapy
- Agriculture and Biological Studies
- GABA and Rice Research
- Reproductive biology and impacts on aquatic species
- Insect-Plant Interactions and Control
- Cytokine Signaling Pathways and Interactions
- RNA Interference and Gene Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Drug Transport and Resistance Mechanisms
- Photosynthetic Processes and Mechanisms
- Paleontology and Stratigraphy of Fossils
- Phytase and its Applications
ZheJiang Academy of Agricultural Sciences
2023-2024
Second Hospital of Tianjin Medical University
2010-2024
Tianjin Medical University
2010-2024
University of Massachusetts Chan Medical School
2017-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Southwest University
2023
Xuzhou Medical College
2023
Zhejiang University
2009-2023
South China University of Technology
2023
University of Science and Technology of China
2021-2022
Abstract A strategy to expand anti‐Stokes shifting from the far‐red deep‐blue region in metal‐free triplet–triplet annihilation upconversion (TTA‐UC) is presented. The method demonstrated by vivo titration of photorelease an anticancer prodrug. This new TTA system has robust brightness and longest shift any reported system. core–shell‐structured prodrug delivery capsules that benefit these properties were developed; they can operate with low‐power density light‐emitting diode light. These...
Amorphous calcium carbonate plays a key role as transient precursor in the early stages of biogenic formation nature. However, due to its instability aqueous solution, there is still rare success utilize amorphous biomedicine. Here, we report mutual effect between paramagnetic gadolinium ions and carbonate, resulting ultrafine nanoclusters presence both occluded highly hydrated carbonate-like environment poly(acrylic acid). Gadolinium confirmed enhance water content high contributes much...
Dental caries is a widespread oral disease that poses significant medical challenge. Traditional prevention methods, primarily the application of fluoride, often fall short in effectively destroying biofilms and preventing enamel demineralization, thereby providing limited efficacy halting progression over time. To address this issue, we have developed green cost-effective synergistic strategy for dental caries. By combining natural sodium phytate chitosan, created chitosan–sodium...
Although high melamine (MEL) intake has been proven to cause serious health problems, MEL is sometimes illegally added milk products and animal feed, arousing food safety concerns. A satisfactory method of detecting in onsite or in-home testing urgent need development. This work aimed explore a rapid, convenient, cost-effective identifying other by colloidal selenium-based lateral flow immunoassay. Colloidal selenium was synthesized L-ascorbic acid reduce seleninic at room temperature. After...
We present a multimodal sensor system for wound assessment and pressure ulcer care. Multiple imaging modalities including RGB, three- dimensional (3-D) depth, thermal, multispectral, chemical sensing are integrated into portable hand-held probe real-time assessment. Analytic quantitative algorithms various assessments tissue composition, measurement in 3-D, temperature profiling, spectral, vapor analysis developed. After each scan, 3-D models of the generated on fly geometric measurement,...
Abstract Despite substantial advances in treating cervical cancer (CC) with surgery, radiation and chemotherapy, patients advanced CC still have poor prognosis significantly variable clinical outcomes due to tumor recurrence metastasis. Therefore, develop more efficacious specific treatments for remains an unmet need. In this study, by virtual screening the SPECS database, we identified multiple novel JAK inhibitor candidates validated their antitumor drug efficacies that were particularly...
Abstract As the key intermediate phase of crystalline calcium carbonate biominerals, amorphous (ACC) remains mysterious in its structures because long‐range disorder and instability. We herein report synthesis ACC nanospheres a water‐deficient organic solvent system. The obtained are very stable under dry conditions. Cryo‐TEM reveals that each consists smaller nanosized clusters. further demonstrate these clusters can precipitate on other substrates to form an ultrathin coating, which should...
Venomous imported fire ants cause significant medical problems. Alkaloids are an important component of ant venom. Piperidine and piperideine alkaloids have been identified in In this study, we studied the venom red ant, Solenopsis invicta Buren, black richteri Forel, hybrid, S. × richteri. Pyridine were detected first time using solid-phase microextraction (SPME) coupled with gas chromatography-mass spectrometry (SPME-GC-MS). The thermal desorption process was manipulated to facilitate...
Abstract Targeting the pivotal pathological processes of acute kidney injury (AKI) and parallelly monitoring treatment process has emerged as an intriguing strategy for timely tailored AKI, especially in phase. Unfortunately, current clinical approaches are restricted to supportive care, which shows limited efficiency. Herein, a multiantioxidant‐cooperative polydopamine‐based nanotheranostic platform (mc‐PDATP) is reported achieve imaging‐assisted time‐sensitive therapy AKI. Benefiting from...
Inflammatory bowel disease (IBD) is a progressive and debilitating inflammatory of the gastrointestinal tract (GIT). Despite recent advances, precise treatment noninvasive monitoring remain challenging.
Abstract In this study, a total of 31 novel isoxazole derivatives containing bisamide moiety were synthesized and evaluated for their insecticidal activity against Plutella xylostella ( P . ). Bioassays indicated that some the target compounds exhibited good particular, compound E26 revealed excellent , with 50% lethal concentration (LC 50 ) value 4.6 μg/mL, which was even better than those chlorpyrifos (7.7 μg/mL), beta‐cypermethrin (12.8 azadirachtin (10.2 μg/mL). These results could be...
The aim of the research presented here was to investigate immunoloregulatory effects 5 saponins: Saikosaponins A (SSA) and D (SSD) from <i>Bupleurum chinese</i> DC (<i>Umbelliferae</i>), Panax Notoginseng Saponin (PNS) Notoginsenoside R1 <i>Panax notoginseng</i> (<i>Araliaceae</i>) (SR1), Anemoside B4 <i>Pulsatilla chinensis</i> Regel (<i>Ranunculaceae</i>) (AB4). To achieve this, endothelial cells were challenged with 10<sup>5</sup> TCID<sub>50</sub>/mL PRRSV for 24 h then treated...
Abstract Background Cysts of Artemia can remain in a dormant state for long periods with very low metabolic rate, and only resume their development the approach favorable conditions. The post-diapause is complicated process involving variety biochemical events. However, intrinsic mechanisms that regulate this are unclear. Results Herein we report specific activation an AMP-activated protein kinase (AMPK) developmental . Using phospho-AMPKα antibody, AMPK was shown to be phosphorylated...
A novel CYPA-targeted, SiO2 encapsulated Au star@AgAu yolk-shell nanostructure (YSNS) was synthesized and used for ovarian cancer early diagnosis therapy.Diverse spectroscopic microscopic methods were utilized to investigate the pattern of nanostructure. In addition, in vitro vivo experiments carried out.It can be found that ratio HAuCl4 AgNO3 played a critical role constitution The as-prepared showed excellent SERS performance, which could as substrate specific sensitivity analysis markers...