Magnus I. Magnusson

ORCID: 0000-0003-2290-1806
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genetic Associations and Epidemiology
  • Advanced Proteomics Techniques and Applications
  • Genomics and Rare Diseases
  • Biological Research and Disease Studies
  • Colorectal Cancer Treatments and Studies
  • vaccines and immunoinformatics approaches
  • Knee injuries and reconstruction techniques
  • BRCA gene mutations in cancer
  • Osteoarthritis Treatment and Mechanisms
  • Genetic factors in colorectal cancer
  • Genomic variations and chromosomal abnormalities
  • Lymphoma Diagnosis and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Iron Metabolism and Disorders
  • T-cell and B-cell Immunology
  • Genetics and Neurodevelopmental Disorders
  • Bioinformatics and Genomic Networks
  • Genetic Syndromes and Imprinting
  • Hemoglobinopathies and Related Disorders
  • Epigenetics and DNA Methylation
  • DNA Repair Mechanisms
  • Folate and B Vitamins Research
  • Immunotherapy and Immune Responses

deCODE Genetics (Iceland)
2018-2024

University of Iceland
2023

Objective Biomarkers for diagnosis and progression of osteoarthritis (OA) are lacking. This study was undertaken to identify circulating biomarkers OA that could predict disease occurrence and/or joint replacement. Methods Using the SomaScan platform, we measured 4,792 proteins in plasma from 37,278 individuals, whom 12,178 individuals had 2,524 undergone We performed a case–control identification potential protein hip, knee, hand OA, prospective Results Among large panel assessed, cartilage...

10.1002/art.41793 article EN Arthritis & Rheumatology 2021-05-13

Discovery of coding variants in genes that confer risk neurodevelopmental disorders is an important step towards understanding the pathophysiology these disorders. Whole-genome sequencing 31,463 Icelanders uncovers a frameshift variant (E712KfsTer10) microtubule-associated protein 1B (MAP1B) associates with ID/low IQ large pedigree (genome-wide corrected P = 0.022). Additional stop-gain MAP1B (E1032Ter and R1664Ter) validate association ID IQ. Carriers have 24% less white matter (WM) volume...

10.1038/s41467-018-05595-6 article EN cc-by Nature Communications 2018-08-21

The TNM system is used to assess prognosis after colorectal cancer (CRC) diagnosis. Other prognostic factors reported include histopathological assessments of the tumour, tumour mutations and proteins in blood. As some these are strongly correlated, it important evaluate independent effects they may have on survival.Tumour samples from 2162 CRC patients were visually assessed for amount stroma, severity lymphocytic infiltrate at margins presence lymphoid follicles. Somatic 2134 individuals....

10.1038/s41416-023-02374-z article EN cc-by British Journal of Cancer 2023-08-18
Coming Soon ...