Kári Stéfansson
- Genetic Associations and Epidemiology
- Epigenetics and DNA Methylation
- Genomic variations and chromosomal abnormalities
- Genomics and Rare Diseases
- Nutrition, Genetics, and Disease
- RNA modifications and cancer
- Genetics and Neurodevelopmental Disorders
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Bioinformatics and Genomic Networks
- BRCA gene mutations in cancer
- Birth, Development, and Health
- Metabolomics and Mass Spectrometry Studies
- Congenital heart defects research
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Osteoarthritis Treatment and Mechanisms
- Asthma and respiratory diseases
- Genetic Syndromes and Imprinting
- RNA Research and Splicing
- Genetic factors in colorectal cancer
- Migraine and Headache Studies
- Autism Spectrum Disorder Research
- Genetic diversity and population structure
- Glycosylation and Glycoproteins Research
University of Iceland
2016-2025
deCODE Genetics (Iceland)
2016-2025
National University Hospital of Iceland
2007-2024
Amgen (Germany)
2016-2024
University of Tartu
2023-2024
University of Exeter
2021-2024
Reykjavík University
2007-2023
RMIT University
2023
Karolinska Institutet
2016-2023
Oslo University Hospital
2023
Sequence variants, including the ε4 allele of apolipoprotein E, have been associated with risk common late-onset form Alzheimer's disease. Few rare variants affecting disease found.
The global endemic of cardiovascular diseases calls for improved risk assessment and treatment. Here, we describe an association between myocardial infarction (MI) a common sequence variant on chromosome 9p21. This study included total 4587 cases 12,767 controls. identified variant, adjacent to the tumor suppressor genes CDKN2A CDKN2B, was associated with disease high significance. Approximately 21% individuals in population are homozygous this their estimated suffering is 1.64 times as...
BackgroundDuring the current worldwide pandemic, coronavirus disease 2019 (Covid-19) was first diagnosed in Iceland at end of February. However, data are limited on how SARS-CoV-2, virus that causes Covid-19, enters and spreads a population.MethodsWe targeted testing to persons living who were high risk for infection (mainly those symptomatic, had recently traveled high-risk countries, or contact with infected persons). We also carried out population screening using two strategies: issuing...
Little is known about the nature and durability of humoral immune response to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).We measured antibodies in serum samples from 30,576 persons Iceland, using six assays (including two pan-immunoglobulin [pan-Ig] assays), we determined that appropriate measure seropositivity was a positive result both pan-Ig assays. We tested 2102 collected 1237 up 4 months after diagnosis by quantitative polymerase-chain-reaction (qPCR)...