Seung‐Jae Lee

ORCID: 0000-0003-2299-4870
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Intracranial Aneurysms: Treatment and Complications
  • Parkinson's Disease Mechanisms and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Neurological and metabolic disorders
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vascular Malformations Diagnosis and Treatment
  • Schizophrenia research and treatment
  • Renal and Vascular Pathologies
  • Cardiovascular Health and Disease Prevention
  • Neurological disorders and treatments
  • Cardiovascular and Diving-Related Complications
  • Ginkgo biloba and Cashew Applications
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Digital Imaging for Blood Diseases
  • Neurological Complications and Syndromes
  • Digital Holography and Microscopy
  • Trigeminal Neuralgia and Treatments
  • Neuroscience and Neuropharmacology Research
  • Moyamoya disease diagnosis and treatment
  • Alzheimer's disease research and treatments
  • Takotsubo Cardiomyopathy and Associated Phenomena

Bucheon University
2017-2025

Soonchunhyang University
2017-2025

Kangbuk Samsung Hospital
2023

Seoul National University
2017-2023

Kwangju Christian Hospital
2022

Dong-Eui University
2022

Kyungpook National University
2002-2019

Catholic University of Korea
2003-2018

Kyung Hee University Hospital at Gangdong
2018

Yeouido St. Mary's Hospital
2018

Several case studies have reported on restless legs syndrome (RLS) associated with stroke. In this study, we investigated the prevalence and lesion topography of poststroke RLS. There were 137 patients ischemic stroke included in study. The diagnosis RLS was made 1 month after index using criteria established by International Study Group. All enrolled underwent magnetic resonance imaging within 7 days onset stroke-related calculated, lesions analyzed. Among patients, 17 (12.4%) diagnosed a...

10.1002/mds.22303 article EN Movement Disorders 2008-09-24

White matter hyperintensities (WMH) have been associated with cognitive impairment in elderly persons and patients Alzheimer disease. However, the role of WMH Parkinson disease (PD) dementia remains to be elucidated.The cohort for this study comprised 71 consecutive PD, all whom completed a clinical assessment, neuropsychologic investigation, magnetic resonance imaging brain. were rated using semiquantitative visual rating system proposed by Scheltens et al.The PD group had significantly...

10.1097/wad.0b013e3181d71a13 article EN Alzheimer Disease & Associated Disorders 2010-05-14

<b><i>Background:</i></b> Cardiac myxomas are rare but the most common cardiac tumors. This study is based on our clinical experience with over a period of 11 years at Sejong General Hospital. We focused embolic complications patients myxoma. <b><i>Methods:</i></b> retrospectively reviewed medical records 59 consecutive myxoma who were treated between January 2000 and March 2011. The divided into two types: type 1, an irregular or villous...

10.1159/000335830 article EN Cerebrovascular Diseases 2012-01-01

Background Fibromyalgia (FM) is a disorder characterized by chronic widespread pain and frequently associated with other symptoms. Patients FM commonly report cognitive complaints, including memory problem. The objective of this study was to investigate the differences in neural correlates working between patients healthy subjects, using functional magnetic resonance imaging (MRI). Methodology/Principal Findings Nineteen 22 subjects performed an n-back task during MRI scan. Functional data...

10.1371/journal.pone.0037808 article EN cc-by PLoS ONE 2012-06-08

Fibromyalgia (FM), characterized by chronic widespread pain, is known to be associated with heightened responses painful stimuli and atypical resting-state functional connectivity among pain-related regions of the brain. Previous studies FM using magnetic resonance imaging (rs-fMRI) have focused on intrinsic connectivity, which maps spatial distribution temporal correlations spontaneous low-frequency fluctuation in MRI (fMRI) data. In current study, rs-fMRI data frequency domain, we...

10.1016/j.pain.2013.05.040 article EN Pain 2013-05-25

Abstract The aim of this study was to examine the effect Ginkgo biloba on antidepressant‐induced sexual dysfunction. ( n =19) and placebo groups =18) were divided; each be administered with respectively for 2 months by means a randomized placebo‐controlled, double‐blind study. results month trial were: (1) there no statistical significant difference from at weeks 2, 4 8 after medication; (2) in comparison baseline, both group showed improvement some part function, which is suggestive...

10.1002/hup.409 article EN Human Psychopharmacology Clinical and Experimental 2002-07-29

This study attempts to explore the clinical features, possible mechanisms and prognosis of neurologic complications in patients with acute aortic dissection (AD).Medical records 278 consecutive AD (165 type A 113 B dissection) over 11.5 years were retrospectively analyzed for history, CT findings, outcome. Neurologic classified into early-onset or delayed-onset complications. Independent t-test Chi-square test (or Fisher exact test) was used comparing different groups. Multivariable logistic...

10.1186/1471-2377-13-46 article EN cc-by BMC Neurology 2013-05-21

Background and purpose Early neurologic deterioration (END) during the acute stage of stroke is clinically important because its association with poor outcomes. The this study was (1) to investigate variables associated END, (2) determine distribution atherosclerotic stenosis (3) clarify relationship between END clinical Methods 516 patients ischemic were included. median follow-up period 31.7 months. defined as a ≥2 point increase in National Institutes Health Stroke Scale (NIHSS), ≥1 level...

10.1371/journal.pone.0185314 article EN cc-by PLoS ONE 2017-09-25

Abstract Background Several studies have suggested that the specific stroke subtype may influence presence of leukoaraiosis in patients with ischemic stroke. We investigated association between and Korean by MRI. Methods There were 594 included this study classified as large artery disease, lacune cardioembolic For large-artery analysis focused on intracranial or extracranial location stenosis, multiplicity stenotic lesions. Leukoaraiosis grading was performed according to Atherosclerosis...

10.1186/1471-2377-8-31 article EN cc-by BMC Neurology 2008-08-07

Cerebrovascular complications (CVCs) frequently occur in patients with acute infective endocarditis (IE). The aim of this study is to describe the clinical findings CVCs and evaluate impact on long-term mortality IE.We retrospectively analyzed 144 who fulfilled modified Duke's criteria for definite left-sided IE. were classified into minor (silent cerebral embolism, TIA stroke an initial Rankin scale ≤ 2) or major (an ≥ 3) CVCs. Cox proportional hazards model was used analysis. Hazard ratio...

10.1186/1471-2377-14-30 article EN cc-by BMC Neurology 2014-02-14

The management and clinical prognosis of incidental intracranial aneurysms in acute ischemic stroke patients have been understudied. We investigated the outcome subjects with incidentally found aneurysms.We consecutively included within 7 days onset. Their demographics, risk factors, subtypes, antithrombotics use modified Rankin scale (mRS) at 3 months after were obtained. CT or MR angiography was used to diagnose aneurysms. development an aneurysmal rupture checked during following...

10.1159/000166842 article EN Cerebrovascular Diseases 2008-01-01

Background and Objectives: Pentraxin 3 (PTX3) was shown to be elevated in the acute phase of myocardial infarction (AMI) have prognostic significance AMI patients.The aim this study estimate whether value PTX3 could used as a biomarker, with global registry coronary events (GRACE) risk assessment tool, patients syndrome (ACS).Subjects Methods: Between July 2007 June 2008, 137 patient subjects (mean age : 61±12 years, M F=108 29) ACS who underwent intervention, but did not prior percutaneous...

10.4070/kcj.2010.40.8.370 article EN Korean Circulation Journal 2010-01-01

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by motor and cognitive dysfunction caused expansion of polyglutamine (polyQ) repeat in exon 1 huntingtin (HTT).In patients, the number glutamine residues polyQ tracts are over 35, it correlated with age onset, severity, progression.Expansion increases propensity for HTT protein aggregation, process known to be implicated neurodegeneration.These pathological aggregates can transmitted from neuron another neuron,...

10.5607/en.2017.26.6.321 article EN Experimental Neurobiology 2017-12-27

Nanostructure surface of titanium implants treated with anodic oxidation, heat, and bisphosphonates, has been introduced to improve osseointegration the implants. However, no information could be found about efficiency these approaches on Ti-6Al-4V alloy surfaces. This study examined drug loading capacity anodized nanotubular surfaces in vitro as well bone response immobilized bisphosphonates (BPs) tibiae rats. was divided into two groups: (1) control group (nontreated); (2) test (anodized,...

10.1002/jbm.b.32769 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2012-08-22

The heart and the brain, most oxygen-dependent organs, may be severely affected after carbon monoxide (CO) exposure.CO induced cardiotoxicity occur as a consequence of moderate to severe CO poisoning, including angina attack, myocardial infarct, arrhythmias, failure.We present rare case poisoning cardiomyopathy with left ventricular (LV) thrombus.It is thought that LV thrombus have been caused decreased function dyskinesis.After short-term anticoagulant therapy, echocardiography findings...

10.4250/jcu.2011.19.2.83 article EN Journal of Cardiovascular Ultrasound 2011-01-01

Whether an association exists between cerebral microbleeds (CMBs) and functional recovery after ischemic stroke is unclear. We aimed to evaluate the CMBs outcome acute stroke.Consecutive patients with were enrolled, all stratified into good poor groups at discharge 6 months by using a modified Rankin Scale score. Cardiovascular risk factors, CMBs, white matter hyperintensities compared these two groups. Logistic regression analysis was used estimate of outcomes.A total 225 121 whom...

10.1017/cjn.2014.19 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2014-09-01
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