A5033866877- Congenital Heart Disease Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Global Health and Surgery
- Inhalation and Respiratory Drug Delivery
- Global Health Workforce Issues
- Inflammasome and immune disorders
- Lymphatic System and Diseases
- Cardiac tumors and thrombi
- Mast cells and histamine
- Diversity and Career in Medicine
- Cardiac Structural Anomalies and Repair
- COVID-19 and healthcare impacts
- Foreign Body Medical Cases
- Surgical Simulation and Training
- Blood transfusion and management
- Pediatric Pain Management Techniques
- Patient Safety and Medication Errors
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiovascular Function and Risk Factors
- Occupational and environmental lung diseases
- Ionic liquids properties and applications
- Travel-related health issues
- Coronary Artery Anomalies
- Shoulder Injury and Treatment
- Extracellular vesicles in disease
Start International
2017-2024
National Institute of Mental Health and Neurosciences
2024
Stanford Medicine
2022
ITMO University
2022
University of Minnesota System
2022
Universidade Federal do Maranhão
2022
Oregon Health & Science University
2017
University of South Florida
1997
Royal Children's Hospital
1994
Guy's Hospital
1988-1993
Rheumatic heart disease is the major cause of valvular in developing nations. Endothelial cells (ECs) are considered crucial contributors to rheumatic disease, but greater insight into their roles progression needed.
To assess how efficient the local team attained skills are after several visits made by international missions in respect to number of coronary artery bypass grafting surgery performed and overall patient outcome. This was a retrospective study that included all patients who were operated on at center being diagnosed with chronic disease from May 2016 December 2023. Patients' demographic data retrieved patients' files coupled theatre record file, entered into structured questionnaire, then,...
Valvular heart disease is common and affects the mitral valve (MV) most frequently. Despite prevalence of MV (MVD), cellular molecular pathways that initiate perpetuate it are not well understood.
Abstract Systemic autoantibody-mediated diseases accelerate chronic cardiovascular disease in humans. In the K/B.g7 mouse model of spontaneous inflammatory arthritis, valvular carditis arises part because Fc receptor–mediated activation macrophages, leading to production pathogenic TNF and IL-6. this study, we explored whether impaired efferocytosis mediated by interaction CD47-expressing apoptotic cells with signal regulatory protein α (SIRPα) on macrophages contributes progression model....
Giant anterior circulation aneurysms and some basilar can cause problems due to their size, the presence of clot in aneurysm difficulty applying a clip without kinking parent vessels or damaging closely applied perforating vessels. By utilising cardiopulmonary bypass via femoro-femoral route patient be cooled below 20°C allowing stopped for up 3/4 hour. This will enable neurosurgeon unhurriedly dissect out fear rupture where necessary open remove aneurysm. draining circulating volume into...
Inflammation is a key driver of cardiovascular pathology, and many systemic autoimmune/rheumatic diseases are accompanied by increased cardiac risk. In the K/B.g7 mouse model coexisting autoantibody-mediated arthritis valvular carditis, valve inflammation depends on macrophage production TNF (tumor necrosis factor) IL-6 (interleukin-6). Here, we sought to determine if other canonical inflammatory pathways participate whether signaling through TNFR1 factor receptor 1) endothelial cells...
ABSTRACT A previously healthy 38-year-old woman presented with new-onset sudden chest pain radiating to the back, associated cough, dyspnea, nausea, vomiting, and gastric fullness after eating a bony fish. diagnosis of gastroesophageal reflux disease was made. After week progressive worsening her symptoms, she referred specialist hospital. There, computed tomography imaging strongly suggested that likely fishbone had penetrated esophagus into mediastinal structures; it seemed have produced...
Humanitarian medical missions attempt to lessen the burden of limited access cardiac surgery in low- and middle-income countries. While organizations express difficulties obtaining follow-up information, there is currently little evidence support various assumptions for lack data. This study examines factors influencing long-term patient follow-ups on repeated short-term across nine
Dear Editor, Parkinson's disease (PD), the second most prevalent neurodegenerative disorder, presents with a combination of motor and non-motor symptoms. Studies indicate that prevalence rate is estimated at 1 to 2 cases per 1000 individuals, approximately 1% in those aged 60 years or older.[1] It characteristically chronic, progression symptoms leads multiple disabilities as advances.[2] Disability may increase due later onset illness A disability certificate mandatory for accessing...
well documented but may be crucial or contribute significantly to surgical performance and, ultimately, the desired clinical results [1] .Sevdalis et al. [2] showed that interaction between members of a team as with environment are determinants merit careful analysis and better understanding.Disruptive elements can defined any event capable compromising an individual's ability complete task.The imposes high level cognitive demand.Additionally, there many introducing disturbances...
Abstract Background: Little is known about emotional quality-of-life in paediatric heart disease low- and middle-income countries where the prevalence of uncorrected lesions high. Research on its predictors these settings key to planning interventions. Methods: Ten-year retrospective cross-sectional study children aged 6–17 years with congenital or acquired 12 was conducted. Emotional functioning score PedsQL TM 4.0 generic core scale data patient-reported limitation sports participation...
Objectives: The concept of visiting heart teams (VHTs) to develop a cardiac program with local resources over the past 50 years has saved many lives but not contributed sustainable infrastructure development. Some regions currently have no substitute for VHTs. Easily treatable congenital (CHD) and rheumatic diseases (RHD) become chronic conditions in adulthood and, together coronary artery disease, lead disability. Reliable data effective concepts programs are lacking.
We have recently reported pathologically elevated plasma histamine levels in adult patients undergoing cardiac surgery throughout the perioperative period. found markedly higher paediatric practice. The priming volume of smallest extracorporeal systems is invariably greater than circulating blood neonates and infants, necessitating use stored donor initial procedure. In 40 cases, arbitrarily selected, sampling from arterial port oxygenator prior to initiation bypass revealed massively...
Abstract Rheumatic heart disease (RHD) is a major cause of valvular in developing nations. Endothelial cells (ECs) are considered crucial contributors to RHD, but greater insight into contributing mechanisms needed. Cdh5 -driven EC lineage tracing the K/B.g7 mouse model autoimmune carditis revealed new capillary lymphatic vessels that develop from valve surface endothelial during progression disease. Human rheumatic valves contained similar lymphatics. Unsupervised clustering mitral...