A5078196570- Musculoskeletal pain and rehabilitation
- Migraine and Headache Studies
- Mental Health Research Topics
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Lymphocytic Leukemia Research
- Trigeminal Neuralgia and Treatments
- Cystic Fibrosis Research Advances
- Inflammatory Bowel Disease
- Healthcare Policy and Management
- Behavioral Health and Interventions
- Psoriasis: Treatment and Pathogenesis
- Health Policy Implementation Science
- Spine and Intervertebral Disc Pathology
- Health disparities and outcomes
- Lung Cancer Treatments and Mutations
- Diabetes Management and Education
- Dermatology and Skin Diseases
- Cancer survivorship and care
- Pain Management and Placebo Effect
- Genomics and Rare Diseases
- Global Health Care Issues
- Pediatric health and respiratory diseases
- Mental Health Treatment and Access
- Cancer Treatment and Pharmacology
- Clinical practice guidelines implementation
Access to Wholistic and Productive Living Institute
2024
Open Health Systems Laboratory
2023
Pharmerit (United States)
2019-2022
University of Washington
2009-2010
Seattle University
2010
Background: To determine whether a Web-based diabetes case management program based in an electronic medical record can improve glycemic control (primary outcome) and diabetes-specific self-efficacy (secondary adults with type 1 diabetes, pilot randomized controlled trial was conducted. Methods: A 12-month tested specialty clinic. Patients 21–49 years old receiving multiple daily injections insulin glargine rapid-acting analogs who had recent A1C >7.0% were eligible for inclusion....
Abstract Objective To describe the impact of migraine on functioning based comprehensive data collection, analysis, and reporting patients' experiences. Background Qualitative research conducted to understand perspectives living with has often focused narrow topics or specific groups patients been selectively reported. Methods interviews 71 participants were during two concept elicitation studies as part Migraine Clinical Outcome Assessment System (MiCOAS) project, an FDA grant‐funded...
The objective of this study was to evaluate the measurement properties Psoriasis Symptom Inventory (PSI), an eight-item patient-reported outcome measure for assessing severity plaque psoriasis symptoms.In prospective, randomized using data from adults with moderate-to-severe psoriasis, patients completed PSI, Dermatology Life Quality Index (DLQI), SF-36v2 Acute, and Patient Global Assessment (PtGA). PSI construct validity assessed Spearman rank correlations between DLQI SF-36; test-retest...
Summary Background Patient‐reported outcome (PRO) measures historically used in inflammatory bowel disease have been considered inadequate to support future drug labelling claims by regulatory agencies. Aims To develop PRO tools for use Crohn's (CD) and ulcerative colitis (UC) following guidance issued the US FDA ISPOR (International Society Pharmacoeconomics Outcomes Research). Methods Concept elicitation cognitive interviews were conducted adult patients (≥18 years) across United States...
To capture patients' perspectives on migraine-related cognitive symptoms during pre-headache, headache, post-headache, and interictal periods.Migraine-related are reported by people with migraine both between attacks. Associated disability, they increasingly viewed as a priority target for treatment. The Migraine Clinical Outcome Assessment System (MiCOAS) project is focused developing patient-centered core set of outcome measures the evaluation treatments. focuses incorporating experience...
Abstract Background There is renewed emphasis on including patients in determining, defining, and prioritizing outcomes for migraine treatment. Objectives To obtain insights directly from people living with their priorities Methods A total of 40 qualitative interviews were conducted as part the Migraine Clinical Outcome Assessment System project, a United States Food Drug Administration grant‐funded program to develop core set patient‐centered outcome measures clinical trials. Interviews...
We examined whether minimum wage policy is associated with access to medical care among low-skilled workers in the United States.We used multilevel logistic regression analyze a data set consisting of individual-level indicators uninsurance and unmet need from Behavioral Risk Factor Surveillance System state-level ecological controls US Census, Bureau Labor Statistics, several other sources all 50 states District Columbia between 1996 2007.Higher rates were significantly reduced odds...
To develop and assess content validity of the Psoriasis Symptom Inventory (PSI), a patient-reported outcome (PRO) measure psoriasis symptoms.Following initial literature exploration input from experts, concept elicitation was conducted in two rounds (focus groups individual interviews) with 59 subjects mild to severe psoriasis. Transcripts were coded identify symptom concepts conceptual framework using ATLAS.ti software. Qualitative analysis clinical expert supported item generation...
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic is an ongoing global health crisis that has had a range of impacts on people living with migraine. Methods Qualitative interviews performed as part the Migraine Clinical Outcome Assessment System project, multi‐stage Food and Drug Administration–grant funded program to develop patient‐centered core set outcome measures for use in migraine clinical trials, offered opportunity explore experience during well examine whether...
To explore the feasibility of using social media-based patient networks to gather qualitative data on patient-reported outcome (PRO) concepts relevant chronic lymphocytic leukemia (CLL).Between August and November 2013, US-residing members PatientsLikeMe online CLL community completed open-ended web-based surveys designed elicit descriptions symptoms, impacts, treatment-related perceptions. Qualitative telephone follow-up interviews were conducted with a subsample respondents. Survey...
Abstract We describe the mixed-methods (qualitative and quantitative) development preliminary validation of Patient Assessment for Low Back Pain–Symptoms (PAL-S), a patient-reported outcome measure use in chronic low back pain (cLBP) clinical trials. Qualitative methods (concept elicitation cognitive interviews) were used to identify refine symptom concepts quantitative (classical test theory Rasch measurement theory) evaluate item- scale-level performance using an iterative approach....
The Symptoms of Major Depressive Disorder Scale (SMDDS) was expressly developed on the basis qualitative data to directly incorporate patients' voices into evaluation treatment benefit in major depressive disorder (MDD) clinical trials. To collect quantitative necessary refine/optimize SMDDS and document its psychometric properties. In this multicenter, observational study, participants with clinically diagnosed MDD completed questionnaires 2 waves. Wave 1 designed refine using Rasch...
PURPOSETo develop a patient-reported outcome measure for capturing visual and ocular symptoms before after implantation of intraocular lenses (IOLs) treatment cataracts.DESIGNQuestionnaire development validation study.METHODSThe Questionnaire Visual Disturbances (QUVID) was developed based on literature instrument review; 13 clinician interviews among ophthalmologists in the United States Europe; 67 hybrid qualitative patient adult patients Australia and/or monofocal, traditional multifocal,...
The Quality of Life-Bronchiectasis (QOL-B) questionnaire and Patient Reported Outcome Measurement Information System Short Form v1.0—Fatigue 7a (PROMIS-F SF-7a) have the potential to measure respiratory fatigue symptoms, respectively, in patients with Mycobacterium avium complex (MAC) lung disease but not yet been evaluated for content validity this population. Semi-structured qualitative interviews were conducted United States a current MAC diagnosis. Concept elicitation (CE) (n = 25...
Patients with cystic fibrosis (CF) experience significant disease burden, including progressive pulmonary decline and reduced survival. This multicenter qualitative study was conducted to develop a new patient-reported outcome (PRO) measure assess the impact of CF on patients' quality life: Cystic Fibrosis Impact Questionnaire (CF-IQ). Semi-structured concept elicitation (CE) interviews patients caregivers documented CF-related symptoms, impacts, treatment experiences. Coded interview data...
The Non-Small Cell Lung Cancer Symptom Assessment Questionnaire (NSCLC-SAQ) was developed to incorporate the patient's perspective into evaluation of clinical benefit in advanced non-small cell lung cancer trials and meet regulatory expectations for doing so. Qualitative evidence supported 7 items covering 5 symptom concepts.This study evaluated measurement properties NSCLC-SAQ's items, overall scale, total score.In this observational cross-sectional study, a purposive sample patients with...
Minimum wage policies have been advanced as mechanisms to improve the economic conditions of working poor. Both positive and negative effects such on health care access hypothesized, but associations yet be thoroughly tested. To examine whether presence minimum in excess federal standard $5.15 per hour was associated with indicators among low-skilled adults age, a cross-sectional analysis 2004 Behavioral Risk Factor Surveillance System data conducted. Self-reported insurance status...