Abstract Background Wilms tumor (WT) is the second most common solid in Africa with both low overall survival (OS) and event-free (EFS) rates. However, no known factors are predicting this poor survival. Objective The study was to determine one-year of WT cases its predictors among children diagnosed pediatric oncology surgical units Mbarara regional referral hospital (MRRH), western Uganda. Methodology Children’s treatment charts files managed for were retrospectively followed up period...

Prematurity contributes greatly to the neonatal mortality burden in sub-Saharan Africa. This study evaluated proportion of preterm death, medical conditions at admission, and determinants neonates intensive care unit (NICU) a tertiary hospital Western Uganda.A prospective cohort 351 consecutively enrolled was conducted from March June 2019. Interviewer-administered questionnaires physical assessment were used obtain socio-demographic clinical data for mothers their neonates. Descriptive...

Background: Acute respiratory tract infections are among the leading causes of child morbidity and mortality worldwide. Although diagnosis acute requires simple outpatient medical techniques care, it is still misdiagnosed primary care physicians, to delayed treatment increased mortality. This study described prevalence common that effectively detect diagnose children presenting with symptoms healthcare physicians in remote settings. Patients Methods: descriptive cross-sectional was conducted...

Iron deficiency anaemia is still a global public health concern with the highest burden among children 6 to 23 months due their rapid growth spurt exceeding breastmilk supply. Therefore, nutritional supply key source of iron attain required nutrients for better and development. This was cross-sectional descriptive study done at Ishaka Adventist Hospital (IAH) Kampala International University Teaching (KIUTH) from April July 2022. Participants were consecutively enrolled in study. Structured...

This study assessed the prevalence and associated factors of pneumonia among children under-five years presenting with acute respiratory symptoms.This was a cross sectional at Pediatric Department Kampala International University - Teaching Hospital, from month April to August 2019. The included 336 aged 2 59 months symptoms pediatric clinic. Pneumonia diagnosis made according World Health Organization definition, modified by chest radiograph. Structured questionnaires were used collect data...

Background: Umbilical cord infections complicate to neonatal sepsis that significantly contributes mortality worldwide. There is paucity of data on the incidence, factors associated with umbilical in western Uganda, yet nursing mothers continue practice potentially dangerous care practices. We described and practices by at a tertiary hospital Uganda. Methods: This was based cross sectional study Uganda between months March June 2019. Two hundred forty (240) neonates aged 2 14 days attending...

Congenital malaria is the presence of parasites in a blood smear obtained from neonate usually within 24 hours to 7 days life. It has for long been regarded rare condition. However, recent data indicate that congenital complicates around 35.9% live births globally, 0–37% Sub-Saharan Africa and about 4–6.1% Eastern Uganda. We present 2-day-old who presented with fever, irritability, failure breastfeed. Laboratory tests indicated had positive Giemsa-stained peripheral Plasmodium falciparum,...

Introduction and importance: The incidence of congenital abdominal wall defects is increasing, but few cases have been reported in the African population. Case presentation: We report a case gastroschisis term neonate who was delivered through spontaneous vaginal delivery (SVD) remote health facility before transfer to tertiary hospital Uganda. Although there no environmental exposure teratogens, major risk factor Gastroschisis, low birth weight, HIV-exposed, mother had not received folic...

Soil-transmitted helminths are so prevalent in the tropics and low developing countries. Pediatric clinical presentation of ascariasis, most common helminth, as intestinal obstruction is not only rare but also less described. We present a case 4-year-old girl with massive ascariasis. She presented 3-day history acute abdominal pain associated vomiting an episode passing long white roundworms, about 5 cm length, through nose. The child had mild constipation passed pellets hard stool once last...

Abstract Background HIV-exposed children are vulnerable to undernutrition. Understanding the prevalence and factors with undernutrition remains essential for developing effective strategies reduce impact of malnutrition among this population. Methods This was a cross sectional, descriptive analytical study determine prevalence, feeding practices, associated uninfected aged 6 18 months in Bushenyi District. The involved 245 mother-child pairs attending four highly active antiretroviral...

Klippel-Trénaunay syndrome is a rare congenital capillary-lymphatic-venous condition characterized by the clinical triad of capillary malformations (port wine stains), varicose veins with or without venous malformations, and bony and/or soft-tissue hypertrophy. It has very low incidence about 1:100,000.We report case 21-day-old neonate Black African female (born in Uganda) who presented macrodactyly ectrodactyly on left foot, as well numerous port stains thoracoabdominal region...

Background. Newborn infections remain a major cause of morbidity and mortality among neonates in low-income countries. Clinical diagnosis for omphalitis such settings is possible but this does not depict the microbiological characteristics involved organisms, clinicians have often prescribed empirical antibiotics with omphalitis, despite an increasing burden antibiotic resistance. Methods. A hospital-based cross-sectional study was conducted to evaluate bacteriology susceptibility patterns...

Sclerema neonatorum (SN) is a rare form of panniculitides with an obscure incidence, aetiology, and pathogenesis. This condition peculiar to preterm neonates, especially those comorbidities such as sepsis, congenital anomalies, heart disease, gastrointestinal respiratory diseases. Usually, it presents within the first seven days life, but may develop few weeks later. Typically, SN manifests diffuse hardening skin subcutaneous tissues that subsequently bind underlying muscle bone, often...

Abstract Introduction Cerebral malaria, caused by Plasmodium falciparum, represents the most severe neurologic complication of malaria. Its association with high morbidity and mortality rates, especially among young children, underscores its clinical significance. In sub-Saharan Africa, including Uganda, cerebral malaria remains a major health challenge, contributing significantly to child rate. Despite advances in control, burden children under five is substantial, reflecting need for...

Abstract Iron deficiency anemia is still a global public health concern with the highest burden among children 6 to 23 months due their rapid growth spurt exceeding breastmilk supply. Therefore, nutritional supply key source of iron attain required nutrients for better and development. This was cross-sectional descriptive study done at Ishaka Adventist Hospital (IAH) Kampala International University Teaching (KIUTH) from April July 2022. Participants were consecutively enrolled in study....

<title>Abstract</title> <bold>Introduction</bold> Cerebral malaria, caused by Plasmodium falciparum, represents the most severe neurologic complication of malaria. Its association with high morbidity and mortality rates, especially among young children, underscores its clinical significance. In this study, we aimed to determine prevalence cerebral malaria identify associated factors children admitted at a tertiary hospital in western Uganda. <bold>Methods</bold> This was cross-sectional,...

Abstract Background Iron deficiency anemia is still a global public health concern with the highest burden among children 6 to 23 months. This because of their rapid growth spurt exceeding what breastmilk can supply. Therefore, nutritional supply key source iron attain required nutrients for better and development. The study aimed determine prevalence, factors associated, value Mentzer index when compared RDW plus microcytosis in IDA diagnosis aged months Southwestern Uganda. Methodology was...

Malaria remains one of the leading health problems developing world, and acute kidney injury (AKI) is a well-recognized complication severe malaria in adults; but clinical importance AKI paediatric not well documented. Knowledge prevalence factors associated with among children key strategies, which can help to reduce burden this vulnerable group. Methodology. A hospital-based prospective cross-sectional descriptive analytic study was carried out at Kiryandongo General Hospital. The involved...

Abstract Background Anorectal malformations (ARMs) range from minor abnormalities such as imperforate anus to complex forms cloaca, and are often associated with other anomalies residual functional stooling problems. The present study aimed evaluate the quality of life (QoL) children after surgical treatment for ARMs at Mbarara Regional Referral Hospital (MRRH) in South-Western Uganda. Methods In this cross-sectional study, we enrolled who had completed between 2014 2021 MRRH. A 23-item...

The "white cerebellum sign" is a striking neuroradiological finding, resulting from diffuse hypodense brain lesions in both cerebral hemispheres while sparing the cerebellum. This indicates widespread ischemic damage or expanded edema associated with loss of white-gray matter differentiation. It commonly reported pediatric cases severe neurological conditions, usually poor prognosis. We present case three-month-old female infant who was managed for confirmed acute bacterial meningitis...

Kerosene and rodenticides are used in many households developing countries. This case report aims to discuss the progression management of a patient with intentional kerosene rodenticide poisoning. To our knowledge, this is first documented blended kerosene-rodenticide poisoning medical literature. describes 23-year-old man who survived after intramuscular self-injection 5 ml mixed into his left upper limb, intent commit suicide. He was admitted hospital following convulsion brief loss...